The corticotrophin-releasing factor/urocortin system regulates white fat browning in mice through paracrine mechanisms [PDF]
, 2015 Objectives: The corticotrophin-releasing factor (CRF)/urocortin system is expressed in the adipose tissue of mammals, but its functional role in this tissue remains unknown.
Clark, S. +10 more
core +3 more sources
Early Overfeed-Induced Obesity Leads to Brown Adipose Tissue Hypoactivity in Rats
Cellular Physiology and Biochemistry, 2013 Background/Aims: Brown adipose tissue activation has been considered a potential anti-obesity mechanism because it is able to expend energy through thermogenesis. In contrast, white adipose tissue stores energy, contributing to obesity.
Douglas L. de Almeida +7 more
doaj +1 more source
The effects of resistance training, testosterone and palm (Phoenix dactylifera L.) pollen extract on the expression of FNDC5 and IGF1 genes in brown adipose tissue in male rats [PDF]
مجله علوم پزشکی فیض (پیوسته), 2023 Background and Aim: The use of testosterone enanthate is popular among athletes, especially resistance sports. Considering the side effects of using testosterone enanthate, it seems necessary to find alternative methods.
Ali Arbati +3 more
doaj
The effect of estrogen on brown adipose tissue activity in male rats
BMC Research Notes, 2022 Objective Centrally administered estrogen can increase sympathetic nerve activity to brown adipose tissue, resulting in thermogenesis. The central thermogenic effects of estrogen have not been investigated in males.
W. Sievers +7 more
doaj +1 more source
RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease
Hepatology, EarlyView., 2022 RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease. Abstract Background and Aims Receptor‐interacting protein kinase 3 (RIPK3) mediates NAFLD progression, but its metabolic function is unclear. Here, we aimed to investigate the role of RIPK3 in modulating mitochondria function, coupled with lipid droplet (LD)
Marta B. Afonso +16 more
wiley +1 more source
mTORC2 sustains thermogenesis via Akt-induced glucose uptake and glycolysis in brown adipose tissue [PDF]
, 2016 Activation of non-shivering thermogenesis (NST) in brown adipose tissue (BAT) has been proposed as an anti-obesity treatment. Moreover, cold-induced glucose uptake could normalize blood glucose levels in insulin-resistant patients.
Albert V +12 more
core +4 more sources
Nature Communications, 2018 Long non-coding RNAs are known to regulate mouse white adipose tissue development and brown adipose tissue program expression. Here, the authors construct a roadmap for human long non-coding RNAs expressed in fetal brown adipose tissue, adult omental and
Chunming Ding +12 more
doaj +1 more source
Sanhuang Xiexin Decoction ameliorates lipid disorders in obese mice via inducing browning of white adipose tissue and activating brown adipose tissue. [PDF]
Chin MedBackground Obesity has become a critical public health challenge worldwide. Prioritizing prevention and tackling root causes—rather than merely managing symptoms—is critical to curbing this pandemic.
Huang Z +14 more
europepmc +2 more sources
PexRAP inhibits PRDM16-mediated thermogenic gene expression [PDF]
, 2017 How the nuclear receptor PPARγ regulates the development of two functionally distinct types of adipose tissue, brown and white fat, as well as the browning of white fat, remains unclear.
Dean, John M +8 more
core +3 more sources
The adipose tissue: something more than a reservoir of energy
Grasas y Aceites, 2009 Adipose tissue is a reservoir of energy and also an organ that contributes to the aesthetics and health of human body working as an endocrine tissue. White adipose tissue, which is formed by unilocular adipose cells, can modify organic homeostasis by ...
Alfonso Valenzuela B, Julio Sanhueza C
doaj +1 more source