Results 61 to 70 of about 171,332 (355)

The Emerging 4D Printing of Shape‐Memory Thermomorphs for Self‐Adaptative Biomedical Implants

Advanced Functional Materials, EarlyView.
4D printing enables the creation of smart implants that adapt to changing conditions in the human body over time. At the core of this technology are shape‐memory thermomorphs (SMTMs). This review offers an in‐depth analysis of 4D printing with SMTMs, emphasizing the latest advancements in smart materials, stimuli, programming principles, and their ...
Aixiang Ding, Fang Tang, Eben Alsberg
wiley   +1 more source

Circadian control of brown adipose tissue

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2021
Disruption of circadian (~24 h) rhythms is associated with an increased risk of cardiometabolic diseases. Therefore, unravelling how circadian rhythms are regulated in different metabolic tissues has become a prominent research focus. Of particular interest is brown adipose tissue (BAT), which combusts triglyceride-derived fatty acids and glucose into ...
Straat, M.E., Hogenboom, R., Boon, M.R., Rensen, P.C.N., Kooijman, S.   +4 more
openaire   +4 more sources

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

Advanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana, Indra Apsite, Leonid Ionov   +2 more
wiley   +1 more source

CD47 differentially regulates white and brown fat function

Biology Open, 2020
Mechanisms that enhance energy expenditure are attractive therapeutic targets for obesity. Previously we have demonstrated that mice lacking cd47 are leaner, exhibit increased energy expenditure, and are protected against diet-induced obesity.
Heather Norman-Burgdolf, Dong Li, Patrick Sullivan, Shuxia Wang   +3 more
doaj   +1 more source

Estradiol regulates brown adipose tissue thermogenesis via hypothalamic AMPK [PDF]

, 2014
Copyright © 2014 Elsevier Inc.
Bisschop, Peter H., Dieguez, Carlos, Fernandez-Mallo, Diana, Fliers, Eric, Gallego, Rosalia, Gonzalez-Garcia, Ismael, Kalsbeek, Andries, Lage, Ricardo, Liu, Ji, Lopez, Miguel, Martinez De Morentin, Pablo Blanco, Martinez-Sanchez, Noelia, Martins, Luis, Morgan, Donald A, Nogueiras, Ruben, Pinilla, Leonor, Rahmouni, Kamal, Ruiz-Pino, Francisco, Saha, Asish K, Tena-Sempere, Manuel   +19 more
core   +4 more sources

A Visible Light‐Responsive Hydrogel to Study the Effect of Dynamic Tissue Stiffness on Cellular Mechanosensing

Advanced Functional Materials, EarlyView.
A visible light‐responsive polyacrylamide‐azobenzene hydrogel enables safe, reversible stiffness control for studying cell mechanobiology without harmful UV exposure. This approach reveals stem cells respond rapidly to mechanical changes, showing altered shape and protein distribution within one hour.
Aafreen Ansari, Sanchyan Bhowmik, Kaiwen Zhang, Chayla L. Reeves, Danielle Vahala, Yu Suk Choi, Amy Gelmi, Alexander N. Combes, Rocky S. Tuan, Vinh X. Truong, John S. Forsythe, Jessica E. Frith   +11 more
wiley   +1 more source

Ultra‐Tiny Gelatin Nanoparticles‐Assisted 3D Stem Cell Spheroids for Engineering Tissue Regeneration

Advanced Healthcare Materials, EarlyView.
GNPs effectively guide the formation of structurally compact and functionally enhanced stem cell spheroids. This GNP‐assisted 3D culture system improves cell–cell and cell‐ECM interactions, leading to superior viability and complexity. Time‐dependent regenerative potential is demonstrated in both bone and skin defects, positioning GNP‐spheroids as a ...
Dream Kim, Woochan Kim, Harshita Sharma, Shinyull Lee, Chaeyeon Park, Sunho Park, Chan Yeong Heo, Jangho Kim   +7 more
wiley   +1 more source

Senescent T Cell Induces Brown Adipose Tissue “Whitening” Via Secreting IFN-γ

Frontiers in Cell and Developmental Biology, 2021
Aging-associated chronic inflammation is a key contributing factor to a cluster of chronic metabolic disorders, such as cardiovascular disease, obesity, and type 2 diabetes.
Xiao-Xi Pan, Kang-Li Yao, Yong-Feng Yang, Qian Ge, Run Zhang, Ping-Jin Gao, Cheng-Chao Ruan, Fang Wu   +7 more
doaj   +1 more source

Polyunsaturated fatty acids stimulate de novo lipogenesis and improve glucose homeostasis during refeeding with high fat diet [PDF]

, 2017
The recovery of body weight after a period of caloric restriction is accompanied by an enhanced efficiency of fat deposition and hyperinsulinemia—which are exacerbated by isocaloric refeeding on a high fat diet rich in saturated and monounsaturated ...
Bianco, Francesca, Cancelliere, Rosa, Crescenzo, Raffaella, Dulloo, Abdul G., Giacco, Antonia, Iossa, Susanna, Liverini, Giovanna, Mazzoli, Arianna   +7 more
core   +1 more source

Microbiota Depletion Impairs Thermogenesis of Brown Adipose Tissue and Browning of White Adipose Tissue [PDF]

Cell Reports, 2019
The relation between gut microbiota and the host has been suggested to benefit metabolic homeostasis. Brown adipose tissue (BAT) and beige adipocytes facilitate thermogenesis to maintain host core body temperature during cold exposure. However, the potential impact of gut microbiota on the thermogenic process is confused. Here, we evaluated how BAT and
Min Li, Min Li, Wanzhu Jin, Catherine Hambly, Baoguo Li, Guanlin Wang, Guanlin Wang, Xueying Zhang, Xueying Zhang, Xue liu, Guanghou Shui, Yingga Wu, Yingga Wu, Hanlin Zhang, John R. Speakman, John R. Speakman, John R. Speakman, Li Li, Sin Man Lam, Chaoqun Niu   +19 more
openaire   +5 more sources