Results 51 to 60 of about 172,968 (298)

Magnetic resonance spectroscopy investigations of brown adipose tissue and isolated brown adipocytes.

Journal of Lipid Research, 1994
Brown adipose tissue and collagenase-isolated brown adipocytes were investigated in rats by means of 1H and 13C nuclear magnetic resonance spectroscopy.
C Zancanaro, R Nano, C Marchioro, A Sbarbati, A Boicelli, F Osculati   +5 more
doaj   +1 more source

Haploinsufficiency of the retinoblastoma protein gene reduces diet-induced obesity, insulin resistance, and hepatosteatosis in mice [PDF]

, 2009
Udgivelsesdato: 2009-JulBrown adipose tissue activity dissipates energy as heat, and there is evidence that lack of the retinoblastoma protein (pRb) may favor the development of the brown adipocyte phenotype in adipose cells. In this work we assessed the
Bonet, M Luisa, Cinti, Saverio, Feddersen, Søren, Kristiansen, Karsten, Madsen, Lise, Mercader, Josep, Murano, Incoronata, Palou, Andreu, Ribot, Joan   +8 more
core   +1 more source

Human Brown Adipose Tissue [PDF]

Cell Metabolism, 2010
The BAT organ is unique in that it has evolved to safely dissipate large amounts of chemical energy--a quality that might be harnessed to help humans deal with a dangerously hypercaloric environment and still remain in good health.
openaire   +2 more sources

Abnormal brown adipose tissue mitochondrial structure and function in IL10 deficiency

EBioMedicine, 2019
Background: Inflammation is the most relevant mechanism linking obesity with insulin-resistance and metabolic disease. It impacts the structure and function of tissues and organs involved in metabolism, such as the liver, pancreatic islets and the ...
José C. de-Lima-Júnior, Gabriela F. Souza, Alexandre Moura-Assis, Rodrigo S. Gaspar, Joana M. Gaspar, Andréa L. Rocha, Danilo L. Ferrucci, Tanes I. Lima, Sheila C. Victório, Ivan L.P. Bonfante, Claudia R. Cavaglieri, José C. Pareja, Sérgio Q. Brunetto, Celso D. Ramos, Bruno Geloneze, Marcelo A. Mori, Leonardo R. Silveira, Gesmar R.S. Segundo, Eduardo R. Ropelle, Lício A. Velloso   +19 more
doaj   +1 more source

Perilipin regulates the thermogenic actions of norepinephrine in brown adipose tissue [PDF]

, 2007
In response to cold, norepinephrine (NE)-induced triacylglycerol hydrolysis (lipolysis) in adipocytes of brown adipose tissue (BAT) provides fatty acid substrates to mitochondria for heat generation (adaptive thermogenesis).
Bianco, Antonio C., Christoffolete, Marcelo A., D'Eon, Tara M., Greenberg, Andrew S., Imachi, Hitomi, Miyoshi, Hideaki, Obin, Martin S., Perfield, James W., II, Ribeiro, Miriam O., Rogers, Nicole H., Souza, Sandra C., Stancheva, Zlatina S., Strissel, Katherine J.   +12 more
core   +1 more source

Roles of FGFs as adipokines in adipose tissue development, remodeling, and metabolism

Frontiers in Endocrinology, 2014
White and brown adipose tissues, which store and burn lipids, respectively, play critical roles in energy homeostasis. Fibroblast growth factors (FGFs) are signaling proteins with diverse functions in development, metabolism, and neural function. Among
Nobuyuki eItoh, Hiroya eOhta
doaj   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Chronic l-menthol-induced browning of white adipose tissue hypothesis: A putative therapeutic regime for combating obesity and improving metabolic health [PDF]

, 2016
Obesity constitutes a serious global health concern reaching pandemic prevalence rates. The existence of functional brown adipose tissue (BAT) in adult humans has provoked intense research interest in the role of this metabolically active tissue in whole-
Andrade, Cl��udia Marlise Balbinotti, Boguszewski, Cesar, Carrillo, Andres E, Flouris, Andreas D, Jamurtas, Athanasios Z, Kawashita, Nair Honda, Koutedakis, Yiannis, Metsios, George S, Nadolnik, Liliya, Sakellariou, Paraskevi, Svensson, Per-Arne, Valente, Angelica   +11 more
core   +1 more source

Coacervates Made of Elastin‐Like Polypeptides Fused with Melanocyte‐Stimulating Hormone and Monocyte Chemoattractant Protein Enhance Skin Wound Healing in Spinal Cord‐Injured Mice

Advanced Healthcare Materials, EarlyView.
Pressure skin wounds are frequent complications after spinal cord injury (SCI), with impaired healing due to vascular and immune deficits. Elastin‐like polypeptides (ELP) fused to α‐MSH (MSH‐ELP) or MCP‐1 (MCP‐ELP) are developed and tested on these wounds. The resulting nanoparticles are non‐toxic and bioactive, and they enhance macrophage recruitment,
Suneel Kumar, Dhruv Patel, Greeshma Manjunath, Shashank Madhavan, Ashley Mathew, Dnyaneshwari Rananavare, Jahnavi Shah, Francois Berthiaume   +7 more
wiley   +1 more source

Oxidative phosphorylation in brown adipose tissue in a type II diabetes mellitus mouse model after forced treadmill running

Бюллетень сибирской медицины
Aim. To study the effect of forced exercises on the content and parameters of oxidative phosphorylation in brown adipose tissue of mice with type II diabetes mellitus.Materials and methods.
A. N. Zakharova, K. G. Milovanova, A. A. Orlova, O. V. Kollantay, I. Yu. Shuvalov, L. V. Kapilevich   +5 more
doaj   +1 more source