Results 31 to 40 of about 172,968 (298)

The corticotrophin-releasing factor/urocortin system regulates white fat browning in mice through paracrine mechanisms [PDF]

, 2015
Objectives: The corticotrophin-releasing factor (CRF)/urocortin system is expressed in the adipose tissue of mammals, but its functional role in this tissue remains unknown.
Clark, S., Contarino, A., Cota, D., Diz-Chaves, Y., Fanelli, F., Grammatopoulos, Dimitris, Lehnert, Hendrik, Lu, B., Markovic, Danijela, Penicaud, L., Tabarin, A.   +10 more
core   +3 more sources

Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction‐associated fatty liver disease

Hepatology, EarlyView., 2022
Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario, David Sebastián, Mireia Casulleras, Marta Duran‐Güell, Roger Flores‐Costa, Ferran Aguilar, Juan José Lozano, Ingrid W. Zhang, Esther Titos, Jing X. Kang, Antonio Zorzano, Makoto Arita, Joan Clària   +12 more
wiley   +1 more source

Recent progress in the study of brown adipose tissue

Cell & Bioscience, 2011
Brown adipose tissue in mammals plays a critical role in maintaining energy balance by thermogenesis, which means dissipating energy in the form of heat.
Yao Xuan, Shan Shifang, Zhang Ying, Ying Hao   +3 more
doaj   +1 more source

Resveratrol and Pterostilbene, Two Analogue Phenolic Compounds, Affect Aquaglyceroporin Expression in a Different Manner in Adipose Tissue [PDF]

, 2018
Aquaglyceroporins (AQPs) are transmembrane channels that mediate glycerol release and glycerol uptake. They are involved in fat metabolism, with implications in obesity. The aim was to determine whether the administration of resveratrol and pterostilbene
Fernández Quintela, Alfredo, González, Marcela, Gómez Zorita, Saioa, Portillo Baquedano, María Puy, Trepiana Arin, Jenifer   +4 more
core   +3 more sources

Enhanced mitochondrial activity reshapes a gut microbiota profile that delays NASH progression

Hepatology, EarlyView., 2022
Improved mitochondrial activity, due to the lack of methylation‐controlled J protein (MCJ), creates a specific microbiota signature that when transferred through cecal microbiota transplantation delays NASH progression by restoring the gut‐liver axis and enhancing hepatic fatty acid oxidation.
María Juárez‐Fernández, Naroa Goikoetxea‐Usandizaga, David Porras, María Victoria García‐Mediavilla, Miren Bravo, Marina Serrano‐Maciá, Jorge Simón, Teresa C. Delgado, Sofía Lachiondo‐Ortega, Susana Martínez‐Flórez, Óscar Lorenzo, Mercedes Rincón, Marta Varela‐Rey, Leticia Abecia, Héctor Rodríguez, Juan Anguita, Esther Nistal, María Luz Martínez‐Chantar, Sonia Sánchez‐Campos   +18 more
wiley   +1 more source

Brown adipose tissue whitening leads to brown adipocyte death and adipose tissue inflammation[S]

Journal of Lipid Research, 2018
In mammals, white adipose tissue (WAT) stores and releases lipids, whereas brown adipose tissue (BAT) oxidizes lipids to fuel thermogenesis. In obese individuals, WAT undergoes profound changes; it expands, becomes dysfunctional, and develops a low-grade
Petra Kotzbeck, Antonio Giordano, Eleonora Mondini, Incoronata Murano, Ilenia Severi, Wiebe Venema, Maria Paola Cecchini, Erin E. Kershaw, Giorgio Barbatelli, Guenter Haemmerle, Rudolf Zechner, Saverio Cinti   +11 more
doaj   +1 more source

The effects of resistance training, testosterone and palm (Phoenix dactylifera L.) pollen extract on the expression of FNDC5 and IGF1 genes in brown adipose tissue in male rats [PDF]

مجله علوم پزشکی فیض (پیوسته), 2023
Background and Aim: The use of testosterone enanthate is popular among athletes, especially resistance sports. Considering the side effects of using testosterone enanthate, it seems necessary to find alternative methods.
Ali Arbati, Hasan Matinhomaee, Mohammad Ali Azarbayjani, Saleh Rahmati   +3 more
doaj  

RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease

Hepatology, EarlyView., 2022
RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease. Abstract Background and Aims Receptor‐interacting protein kinase 3 (RIPK3) mediates NAFLD progression, but its metabolic function is unclear. Here, we aimed to investigate the role of RIPK3 in modulating mitochondria function, coupled with lipid droplet (LD)
Marta B. Afonso, Tawhidul Islam, Julie Magusto, Ricardo Amorim, Véronique Lenoir, Rui F. Simões, José Teixeira, Liana C. Silva, Dominique Wendum, Isabelle Jéru, Corinne Vigouroux, Rui E. Castro, Paulo J. Oliveira, Carina Prip‐Buus, Vlad Ratziu, Jérémie Gautheron, Cecília M. P. Rodrigues   +16 more
wiley   +1 more source

Does Adipose Tissue Thermogenesis Play a Role in Metabolic Health?

Journal of Obesity, 2013
The function ascribed to brown adipose tissue in humans has long been confined to thermoregulation in neonates, where this thermogenic capacity was thought lost with maturation.
Craig Porter, Elisabet Børsheim, Labros S. Sidossis   +2 more
doaj   +1 more source

PVAT and Its Relation to Brown, Beige, and White Adipose Tissue in Development and Function

Frontiers in Physiology, 2018
Adipose tissue is commonly categorized into three types with distinct functions, phenotypes, and anatomical localizations. White adipose tissue (WAT) is the major energy store; the largest depots of WAT are found in subcutaneous or intravisceral sites ...
Staffan Hildebrand, Jasmin Stümer, Alexander Pfeifer   +2 more
doaj   +1 more source