Results 41 to 50 of about 25,250 (236)
Brugada Syndrome and GPD1L: Definite Genotype-Phenotype Association?
CardiogeneticsThe GPD1L gene encodes a small cytoplasmic protein that is involved in the regulation of sodium currents. Alterations in this gene have been associated with Brugada syndrome.
Andrea Greco +10 more
doaj +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Schematic overview of the experimental and computational framework for investigating hiPSC‐CM electrophysiology with MEA systems. The MEA‐based model integrates experimental data with phenotype‐specific ionic models and tissue‐level heterogeneity.
Sofia Botti +2 more
wiley +1 more source
Shortening of the Short Refractory Periods in Short QT Syndrome. [PDF]
, 2017 BACKGROUND: Diagnosis of short QT syndrome (SQTS) remains difficult in case of borderline QT values as often found in normal populations. Whether some shortening of refractory periods (RP) may help in differentiating SQTS from normal subjects is unknown.
Cardin, C +10 more
core +3 more sources
Reanalysis and reclassification of rare genetic variants associated with inherited arrhythmogenic syndromes [PDF]
, 2020 Background: Accurate interpretation of rare genetic variants is a challenge for clinical translation. Updates in recommendations for rare variant classification require the reanalysis and reclassification.
Abou Tayoun +27 more
core +1 more source
Annals of Noninvasive Electrocardiology, Volume 30, Issue 4, July 2025.ABSTRACT Background Ablation of the cavo‐tricuspid isthmus (CTI) is the standard treatment for typical atrial flutter. High‐power strategies have been described to improve lesion efficacy and durability. Objective To compare the acute success, safety, and long‐term outcomes of two strategies of high‐power CTI ablation using 8‐mm gold‐tip nonirrigated ...
Wael Zaher +3 more
wiley +1 more source
Role of pharmacotherapy in Brugada syndrome [PDF]
, 2004 In patients who undergo aborted sudden cardiac death or syncope of unknown origin (symptomatic Brugada syndrome), no one argues that the implantation of an ICD is the first-line therapy regardless of the findings of the EP study.
Tsuchiya, Takeshi
core +1 more source
Genetics update: monogenetics, polygene disorders and the quest for modifying genes [PDF]
, 2018 The genetic channelopathies are a broad collection of diseases. Many ion channel genes demonstrate wide phenotypic pleiotropy, but nonetheless concerted efforts have been made to characterise genotype-phenotype relationships.
Symonds, Joseph D., Zuberi, Sameer M.
core +1 more source
Sumatriptan Induced Brugada Syndrome, a Rare Presentation of a Commonly Used Drug
Clinical Case Reports, Volume 13, Issue 6, June 2025.ABSTRACT We aim to highlight an important and rare association of Brugada Syndrome with a commonly used medication, Sumatriptan, which is used as an aborting Migraine headaches. This life‐threatening condition needs early diagnosis and prompt management with vigilant follow‐up for better patient outcomes.
Phool Iqbal +7 more
wiley +1 more source
Brugada-type ECG associated with pectus excavatum [PDF]
, 2015 Brugada phenocopies (BrP) are new clinical entities characterized by an ECG pattern that is identical to type 1 or type 2 Brugada pattern, despite the absence of the true congenital Brugada syndrome (BrS).
Ghazali, Aiham +3 more
core +1 more source
Intermittent Brugada syndrome in an anorexic adolescent girl [PDF]
, 2014 We report an anorexic adolescent girl with an intermittent Brugada syndrome. A 14-year-old anorexic girl with a body mass index (BMI) of 13.15kg/m2 was admitted in the acute state of the disease with an ST elevation in V1 and V2, suggestive of Brugada ...
Docx, Martine K.F. +6 more
core +1 more source