Results 211 to 220 of about 78,184 (307)

Energigräsutveckling i USA [PDF]

, 2001
Olsson (BTK), Rolf
core  

BTK Inhibitor M7583 [PDF]

, 2020
openaire   +1 more source

Fibrinogen‐Like Protein 2 Modulates B Cell Mucosal Immunity by Suppressing Receptor for Activated C‐Kinase 1‐Mediated AKT Phosphorylation

MedComm, Volume 7, Issue 4, April 2026.
In our study, B cells are activated with the assistance of Breg and Tfh cells, subsequently differentiating into IgA+ plasma cells. These plasma cells produce secretory IgA (sIgA) at mucosal surfaces to combat viral and parasitic infections. Mechanistically, Fgl2 directly binds to Rack1.
Jiang Chang, Da Huang, Wei Yuan, Jianing Tang, Jingzhi Yang, Yuying Chen, Zhize Yuan, Yizhi Wu, Di Wu, Weiming Yan, Qin Ning   +10 more
wiley   +1 more source

„A filozófiai irodalomnak a legnehezebb könyve”

Elpis
Attila Hangai, Kosztasz Rosta
doaj   +1 more source

Comparison of drug-coated balloons and plain old balloon angioplasty in hemodialysis patients with Below-The-Knee artery disease. [PDF]

Diab Vasc Dis Res
Jin ZY, Li CM, Ma LB, Wen JH, Ren HL, Wang SX.   +5 more
europepmc   +1 more source

Extracellular and Membrane Protein: Structure, Biological Functions, Diseases, and an Emerging Modality for Drug Discovery

MedComm, Volume 7, Issue 4, April 2026.
Targeted protein degradation represents a paradigm shift from traditional protein inhibition to complete protein elimination. This is achieved through three main strategies for degrading extracellular and membrane proteins: recruitment of cell‐surface LTRs, engagement of intracellular proteins, and receptor‐independent mechanisms.
Mengqing Zhao, Wenhao Yin, Jianjian Han, Huimin Wang, Zheng Liu, Lilong Liu, Wuxiang Mao   +6 more
wiley   +1 more source

Pairing Spruce Budworm Control and Minimal Understory Perturbations: Effects of Btk Spraying Frequency in Boreal Forests. [PDF]

Ecol Evol
Robitaille M, Pothier D, Pellerin S.
europepmc   +1 more source

Systematic Proteomic Characterization of EV‐A71‐Infected Mice Identifies Dynamic Molecular Changes and Therapeutic Targets

MedComm, Volume 7, Issue 4, April 2026.
Time‐resolved multi‐omics of EV‐A71‐infected BALB/c mice uncovered dynamic host responses, revealing rapid neutrophil extracellular traps (NETs) activation as a key event. Screened drugs (kinase inhibitors) suppressed viral replication in vitro and in vivo, suggesting the promise of targeting host phosphorylation networks as a viable antiviral strategy.
Wanjun Peng, Qiaochu Wang, Binbin Zhao, Lihong Zhang, Jing Wu, Xiaohui Wei, Na Rong, Zhaohua Wang, Kaihui Liu, Jiangfeng Liu, Juntao Yang, Jiangning Liu   +11 more
wiley   +1 more source

Computational hybrid framework integrating clinical-mutation profiling and physics-based simulations to predict structural tolerance of Bruton tyrosine kinase (BTK) and sustained ARQ 531 binding. [PDF]

Curr Res Struct Biol
Khan A, Sawali MA, Shkoor M, Hasssan F, Al-Zoubi RM, Alshabrmi FM, Crovella S, Agouni A.   +7 more
europepmc   +1 more source

Targeting BTK with ibrutinib in relapsed or refractory mantle-cell lymphoma.

New England Journal of Medicine, 2013
Michael L. Wang, S. Rule, P. Martin, A. Goy, R. Auer, B. Kahl, W. Jurczak, R. Advani, J. Romaguera, Michael E. Williams, J. Barrientos, E. Chmielowska, J. Radford, S. Stilgenbauer, M. Dreyling, W. Jędrzejczak, Peter W M Johnson, S. Spurgeon, Lei Li, L. Zhang, K. Newberry, Zhishuo Ou, N. Cheng, B. Fang, J. Mcgreivy, F. Clow, J. Buggy, B. Chang, D. Beaupre, L. Kunkel, K. Blum   +30 more
semanticscholar   +1 more source