Results 51 to 60 of about 21,847 (205)

Different Stakeholders, Different Pathways: How Capacity Profiles Shape Managerial Priorities for Beneficiaries and Staff in Decision‐Making

Nonprofit Management and Leadership, EarlyView.
ABSTRACT This study investigates how combinations of organizational capacities shape nongovernmental organization (NGO) managers' prioritization of staff and beneficiaries. While stakeholder theory identifies which stakeholders' interests attract attention, it offers limited guidance on how managers ultimately prioritize among stakeholders in decision ...
Robbie Waters Robichau, Tara Kolar Bryan, Rebekah St. Clair Sims   +2 more
wiley   +1 more source

Clinical feasibility of endovascular recanalization with intravascular ultrasound-guided wiring for chronic total occlusion of below-the-knee arteries

CVIR Endovascular, 2023
Background Revascularization with endovascular therapy (EVT) for complex below-the-knee (BTK) chronic total occlusion (CTO) remains a challenging problem.
Naoki Hayakawa, Satoshi Kodera, Hiromi Miwa, Shinya Ichihara, Satoshi Hirano, Masataka Arakawa, Yasunori Inoguchi, Shunichi Kushida   +7 more
doaj   +1 more source

Fingerprinting Superconductors by Disentangling Andreev and Quasiparticle Currents Across Tunable Tunnel Junctions

Small, EarlyView.
Tunneling Andreev reflection spectroscopy leverages the exponential sensitivity of tunneling current to distinguish between a variety of superconducitng order parameters. Here it is shown that the additivity of excess decay rate enables clear separation of Andreev and quasiparticle currents, fingerprinting the existence of sign changing superconducting
Petro Maksymovych, Sang Yong Song, Benjamin Lawrie, Wonhee Ko, Jose L. Lado   +4 more
wiley   +1 more source

Irreversible inhibition of BTK kinase by a novel highly selective inhibitor CHMFL-BTK-11 suppresses inflammatory response in rheumatoid arthritis model

Scientific Reports, 2017
BTK plays a critical role in the B cell receptor mediated inflammatory signaling in the rheumatoid arthritis (RA). Through a rational design approach we discovered a highly selective and potent BTK kinase inhibitor (CHMFL-BTK-11) which exerted its ...
Hong Wu, Qiong Huang, Ziping Qi, Yongfei Chen, Aoli Wang, Cheng Chen, Qianmao Liang, Jinghua Wang, Wensheng Chen, Jin Dong, Kailin Yu, Chen Hu, Wenchao Wang, Xiaochuan Liu, Yuanxin Deng, Li Wang, Beilei Wang, Xiaoxiang Li, Nathanael S. Gray, Jing Liu, Wei Wei, Qingsong Liu   +21 more
doaj   +1 more source

Artificial intelligence empowers targeted protein degradation: Core technological innovations, multi‐scenario applications, and translational prospects

Smart Molecules, EarlyView.
AI is transforming TPD by improving the design, prediction, and optimization of degraders such as PROTACs, molecular glues, and LYTACs. This review summarizes key AI‐driven advances, highlights applications across drug discovery stages, and discusses remaining challenges and future directions for accelerating the development of therapies against ...
Shuanglin Qin, Rui Peng, Guangshuai Zhang, Si Yan, Jin Xiao, Zishu Liu, Ziyu Tan, Qingqing Xie, Shangjie Li, Wei Luo, Xiaohe Xiao   +10 more
wiley   +1 more source

STRATIFIED ADAPTATION: Infrastructure, Elevation, and Cascading Floods in the Urban Mekong Delta

International Journal of Urban and Regional Research, EarlyView.
Abstract Flood‐prone cities in the global South are increasingly the target of infrastructure projects aimed at building climate ‘resilience’. At the same time, residents of these cities take adaptation to flooding into their own hands. In this article we examine the interrelationship between household‐scale and urban‐scale flood mitigation projects in
Lizzie Yarina, Vuong Kha Tu, Tran Kim Bao, Ly Quoc Dang   +3 more
wiley   +1 more source

Ismétlés és innováció drámai művekben

Digitális Bölcsészet
Tanulmányunkban egy olyan módszert ismertetünk, amellyel drámai szereplők megszólalásainak hírértéke mérhető össze kvantitatív módon. Innovatívnak tekinthető minden olyan szereplő, aki gyakran dolgoz ki a korábbiaktól eltérő jelentést; fenntartó vagy ...
Botond Szemes, Mihály Nagy
doaj   +1 more source

Internal Consistency of the Hadlock Estimated Fetal Weight Reference: Methodological Analysis

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To assess the internal consistency of the Hadlock normal range for estimated fetal weight (EFW) and its clinical implications. Design Methodological analysis and retrospective observational audit. Setting Tertiary maternity hospital in Oxford, UK. Population Women with a non‐anomalous singleton pregnancy.
Theophilus K. Adu‐Bredu, Clement Twumasi, Sam Mathewlynn, Lawrence Impey, Christos Ioannou   +4 more
wiley   +1 more source

Second primary cancers in lymphoplasmacytic lymphoma/Waldenström macroglobulinaemia—cumulative burden without generalized excess cancer risk

British Journal of Haematology, EarlyView.
Summary Second primary cancers (SPCs) are a survivorship concern in lymphoplasmacytic lymphoma/Waldenström macroglobulinaemia (LPL/WM), but estimates may be influenced by competing mortality and surveillance. We assessed cumulative incidence, relative risk and predictors of SPCs. We studied 521 patients diagnosed with LPL/WM in Region Zealand, Denmark,
Lars Munksgaard, Lars Moeller Pedersen, Lise Mette Rahbek Gjerdrum   +2 more
wiley   +1 more source

Előszó a tematikus blokkhoz

Elpis, 2017
Idestova két és fél éve hunyt el fiatalon, tragikus hirtelenséggel Losonczi Péter barátunk, filozófustársunk. Az Elpis jelen száma a Péter emlékére rendezett magyar nyelvű konferencia előadásaiból közöl válogatást.
Gábor Boros, Miklós Vassányi
doaj