An Updated Overview of the Emerging Role of Patch and Film-Based Buccal Delivery Systems [PDF]
Pharmaceutics, 2021 Buccal mucosal membrane offers an attractive drug-delivery route to enhance both systemic and local therapy. This review discusses the benefits and drawbacks of buccal drug delivery, anatomical and physiological aspects of oral mucosa, and various in ...
Shery Jacob +5 more
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Development, Characterization, and Ex Vivo Assessment of Elastic Liposomes for Enhancing the Buccal Delivery of Insulin [PDF]
Pharmaceutics, 2021 Buccal drug delivery is a suitable alternative to invasive routes of drug administration. The buccal administration of insulin for the management of diabetes has received substantial attention worldwide.
Santosh Bashyal +5 more
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Factors affecting the buccal delivery of deformable nanovesicles based on insulin–phospholipid complex: an in vivo investigation [PDF]
Drug Delivery, 2020 Deformable nanovesicles (DNVs) have been used in the buccal delivery of biomacromolecules due to their ability to enhance drug penetration. However, no breakthroughs have been made until now due to limited understanding of the factors affecting in vivo ...
Yuqi Yang +6 more
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Concept for a Unidirectional Release Mucoadhesive Buccal Tablet for Oral Delivery of Antidiabetic Peptide Drugs Such as Insulin, Glucagon-like Peptide 1 (GLP-1), and their Analogs [PDF]
Pharmaceutics, 2023 Injectable peptides such as insulin, glucagon-like peptide 1 (GLP-1), and their agonists are being increasingly used for the treatment of diabetes. Currently, the most common route of administration is injection, which is linked to patient discomfort as ...
Anubhav Pratap-Singh +3 more
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Deformable Nanovesicle-Loaded Gel for Buccal Insulin Delivery [PDF]
Pharmaceutics, 2022 Deformable nanovesicles (DNVs) have been widely used in oral mucosal delivery studies of biomolecular drugs. However, their development for oral mucosal preparations has been limited by their physical and chemical instability, the need for small oral ...
Yiyue Guo +6 more
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Advances in Nanoparticulate Drug Delivery Approaches for Sublingual and Buccal Administration [PDF]
Frontiers in Pharmacology, 2019 The sublingual and buccal routes of administration have significant advantages for both local and systemic drug delivery. They have shown to be an effective alternative to the traditional oral route, especially when fast onset of action is required ...
Susan Hua, Susan Hua
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Advancements in Buccal Drug Delivery: Polymers and Their Applications
RGUHS Journal of Pharmaceutical SciencesBuccal drug delivery offers a promising alternative to conventional oral routes by facilitating the rapid and efficient absorption of therapeutics directly through the mucosal tissues lining the oral cavity.
Shardor Ambarish G +2 more
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Sublingual and Buccal Delivery: A Historical and Scientific Prescriptive [PDF]
PharmaceuticsIn this review, our intention was to shed some light on the history of sublingual and buccal delivery over the past 75 years. By searching the query sublingual and buccal, we noticed four steady growth periods in the number of publications between 1950 ...
Sina Bahraminejad, Hassan Almoazen
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Fast-Dissolving Nifedipine and Atorvastatin Calcium Electrospun Nanofibers as a Potential Buccal Delivery System [PDF]
Pharmaceutics, 2022 Geriatric patients are more likely to suffer from multiple chronic diseases that require using several drugs, which are commonly ingested. However, to enhance geriatric patients’ convenience, the electrospun nanofiber system was previously proven to be a
Hassa A. Alshaya +13 more
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Development and Characterization of Inkjet Printed Edible Films for Buccal Delivery of B-Complex Vitamins [PDF]
Pharmaceuticals, 2020 Buccal films containing two vitamins, i.e., thiamine hydrochloride (THCl) and nicotinic acid (NA), were fabricated via two-dimensional (2D) inkjet printing.
Georgios Eleftheriadis +7 more
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