Results 11 to 20 of about 1,569,840 (207)
High-Payload Buccal Delivery System of Amorphous Curcumin-Chitosan Nanoparticle Complex in Hydroxypropyl Methylcellulose and Starch Films. [PDF]
Int J Mol Sci, 2021 Oral delivery of curcumin (CUR) has limited effectiveness due to CUR’s poor systemic bioavailability caused by its first-pass metabolism and low solubility.
Lim LM, Hadinoto K.
europepmc +2 more sources
Fabrication of 3D Printed Hollow Microneedles by Digital Light Processing for the Buccal Delivery of Actives [PDF]
ACS Biomaterials Science & Engineering, 2023 In the present study, two different microneedle devices were produced using digital light processing (DLP). These devices hold promise as drug delivery systems to the buccal tissue as they increase the permeability of actives with molecular weights ...
Paraskevi Kyriaki Monou +10 more
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Chitosan gels for buccal delivery of Schinus molle L. essential oil in dogs: characterization and antimicrobial activity in vitro [PDF]
Anais da Academia Brasileira de Ciências, 2020 Periodontal disease is considered the main oral cavity disorder in dogs. Essential oils have the potential for use in the prevention and treatment of oral diseases. The antimicrobial activity of Schinus molle L.
MELINA C.C. ALVES +10 more
doaj +2 more sources
International Journal of Nanomedicine, 2021 Santosh Bashyal,1 Jo-Eun Seo,1 Taekwang Keum,1,2 Gyubin Noh,1,2 Shrawani Lamichhane,1,2 Jeong Hwan Kim,1,2 Chang Hyun Kim,3 Young Wook Choi,3 Sangkil Lee1,2 1College of Pharmacy, Keimyung University, Daegu, Republic of Korea; 2Center for Forensic ...
Bashyal S +8 more
doaj +3 more sources
Разработка и регистрация лекарственных средств, 2021 Introduction. Buccal drug delivery has a number of advantages over oral administration: ease of application, good blood supply to the buccal mucosa, drug can enter the systemic circulation directly, avoiding the "first pass effect through the liver", and
A. S. Viktorova +5 more
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In Vitro and Ex Vivo Evaluation of Tablets Containing Piroxicam-Cyclodextrin Complexes for Buccal Delivery. [PDF]
Pharmaceutics, 2019 In the current study, the development of mucoadhesive tablets for buccal delivery of a non-steroidal anti-inflammatory drug was investigated. Binary complexes with piroxicam and cyclodextrins (β-cyclodextrin (β-CD), methylated-β-cyclodextrin (Me-β-CD ...
Kontogiannidou E +11 more
europepmc +2 more sources
Pharmaceutics, 2023 Injectable peptides such as insulin, glucagon-like peptide 1 (GLP-1), and their agonists are being increasingly used for the treatment of diabetes. Currently, the most common route of administration is injection, which is linked to patient discomfort as ...
Anubhav Pratap-Singh +3 more
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Gels, 2022 Carvedilol (CRV) is a non-selective third generation beta-blocker used to treat hypertension, congestive heart failure and angina pectoris. Oral administration of CRV showed poor bioavailability (25%), which might be ascribed to its extensive first-pass ...
El-Sayed Khafagy +13 more
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A Comprehensive Development Strategy in Buccal Drug Delivery [PDF]
AAPS PharmSciTech, 2010 This work combines several methods in an integrated strategy to develop a matrix for buccal administration. For this purpose, tablets containing selected mucoadhesive polymers loaded with a model drug (omeprazole), free or in a complexed form with cyclodextrins, and in the absence and presence of alkali agents were subjected to a battery of tests ...
Ana Figueiras +2 more
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Mucoadhesive Interpolyelectrolyte Complexes for the Buccal Delivery of Clobetasol. [PDF]
Polymers (Basel), 2018 This work aimed to investigate the feasibility to design: (a) a mucoadhesive interpolyelectrolyte complex (IPEC) loaded with clobetasol propionate (CP) intended to treat oral lichen planus and (b) individuate an orodispersible dosage form suitable for its administration.
Garipova VR +4 more
europepmc +5 more sources