Results 11 to 20 of about 1,568,027 (370)
Lidocaine loaded gelatin/gelatinized tapioca starch films for buccal delivery and the irritancy evaluation using chick chorioallantoic membrane [PDF]
Saudi Pharmaceutical Journal, 2019 The aim of this study was to confirm the feasibility of gelatin/gelatinized tapioca starch (α st) films for buccal delivery and to evaluate their irritancy. Lidocaine (LB) and lidocaine hydrochloride (LH) were used as model drugs and glycerin was used as
Suchipha Wannaphatchaiyong +4 more
doaj +3 more sources
Fabrication of 3D Printed Hollow Microneedles by Digital Light Processing for the Buccal Delivery of Actives [PDF]
ACS Biomaterials Science & Engineering, 2023 In the present study, two different microneedle devices were produced using digital light processing (DLP). These devices hold promise as drug delivery systems to the buccal tissue as they increase the permeability of actives with molecular weights ...
Paraskevi Kyriaki Monou +10 more
openalex +2 more sources
Aerosil in Solid-state Buccal Film for Improved and Sustained Delivery of Valsartan: Molecular Docking Studies [PDF]
Chemical and Biochemical Engineering Quarterly, 2023 To overcome low oral bioavailability and short biological half-life, improved and sustained buccal delivery of valsartan has been proposed. Valsartan film with colloidal silicon dioxide has been prepared using HPMC as mucoadhesive polymer matrix by ...
R. Swain +5 more
doaj +4 more sources
Chitosan gels for buccal delivery of Schinus molle L. essential oil in dogs: characterization and antimicrobial activity in vitro [PDF]
Anais da Academia Brasileira de Ciências, 2020 Periodontal disease is considered the main oral cavity disorder in dogs. Essential oils have the potential for use in the prevention and treatment of oral diseases. The antimicrobial activity of Schinus molle L.
MELINA C.C. ALVES +10 more
doaj +2 more sources
International Journal of Nanomedicine, 2021 Santosh Bashyal,1 Jo-Eun Seo,1 Taekwang Keum,1,2 Gyubin Noh,1,2 Shrawani Lamichhane,1,2 Jeong Hwan Kim,1,2 Chang Hyun Kim,3 Young Wook Choi,3 Sangkil Lee1,2 1College of Pharmacy, Keimyung University, Daegu, Republic of Korea; 2Center for Forensic ...
Bashyal S +8 more
doaj +3 more sources
Разработка и регистрация лекарственных средств, 2021 Introduction. Buccal drug delivery has a number of advantages over oral administration: ease of application, good blood supply to the buccal mucosa, drug can enter the systemic circulation directly, avoiding the "first pass effect through the liver", and
A. S. Viktorova +5 more
doaj +2 more sources
Pharmaceutics, 2023 Injectable peptides such as insulin, glucagon-like peptide 1 (GLP-1), and their agonists are being increasingly used for the treatment of diabetes. Currently, the most common route of administration is injection, which is linked to patient discomfort as ...
Anubhav Pratap-Singh +3 more
doaj +2 more sources
In Vitro and Ex Vivo Evaluation of Tablets Containing Piroxicam-Cyclodextrin Complexes for Buccal Delivery. [PDF]
Pharmaceutics, 2019 In the current study, the development of mucoadhesive tablets for buccal delivery of a non-steroidal anti-inflammatory drug was investigated. Binary complexes with piroxicam and cyclodextrins (β-cyclodextrin (β-CD), methylated-β-cyclodextrin (Me-β-CD ...
Kontogiannidou E +11 more
europepmc +2 more sources
Gels, 2022 Carvedilol (CRV) is a non-selective third generation beta-blocker used to treat hypertension, congestive heart failure and angina pectoris. Oral administration of CRV showed poor bioavailability (25%), which might be ascribed to its extensive first-pass ...
El-Sayed Khafagy +13 more
doaj +2 more sources
BUCCAL DRUG DELIVERY SYSTEM: AN OVERVIEW ABOUT DOSAGE FORMS AND RECENT STUDIES [PDF]
, 2020 Management of illness through medication is entering a new era in which growing number of novel drug delivery systems are being employed and are available for therapeutic use.
GÜNEŞ, Meliha +2 more
core +4 more sources