Results 11 to 20 of about 15,112 (249)

Pharmacokinetic Aspects of Nanoparticle-in-Matrix Drug Delivery Systems for Oral/Buccal Delivery [PDF]

Frontiers in Pharmacology, 2019
Oral route maintains its predominance among the ones used for drug delivery, especially when medicines are self-administered. If the dosage form is solid, therapy gains in dose precision and drug stability.
Renata Carvalho Feitosa, Renata Carvalho Feitosa, Danilo Costa Geraldes, Danilo Costa Geraldes, Viviane Lucia Beraldo-de-Araújo, Juliana Souza Ribeiro Costa, Juliana Souza Ribeiro Costa, Laura Oliveira-Nascimento   +7 more
doaj   +2 more sources

Mechanisms of deformable nanovesicles based on insulin-phospholipid complex for enhancing buccal delivery of insulin [PDF]

International Journal of Nanomedicine, 2018
You Xu,1,2 Xing Zhang,1,2 Yun Zhang,1,2 Jun Ye,1,2 Hong-Liang Wang,1,2 Xuejun Xia,1,2 Yuling Liu1,2 1State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & ...
Xu Y, Zhang X, Zhang Y, Ye J, Wang HL, Xia X, Liu Y   +6 more
doaj   +2 more sources

Development and Characterization of Chitosan Microparticles-in-Films for Buccal Delivery of Bioactive Peptides [PDF]

Pharmaceuticals, 2019
Nowadays, bioactive peptides are used for therapeutic applications and the selection of a carrier to deliver them is very important to increase the efficiency, absorption, release, bioavailability and consumer acceptance.
Patrícia Batista, Pedro Castro, Ana Raquel Madureira, Bruno Sarmento, Manuela Pintado   +4 more
doaj   +2 more sources

Boosting buccal drug absorption: Mechanistic insights into bilosome-mediated delivery [PDF]

International Journal of Pharmaceutics: X
Effective buccal drug delivery is limited by the barrier properties of the mucosa, necessitating innovative systems to enhance permeability without compromising tissue integrity.
Eleftheria Pantazoglou, Scarlett Zeiringer, Matteo Tollemeto, Nazanin Zanjanizadeh Ezazi, Zhongyang Zhang, Leticia Hosta-Rigau, Jette Jacobsen, Ramona Jeitler, Eva Roblegg, Line Hagner Nielsen   +9 more
doaj   +2 more sources

Overview and Future Potential of Fast Dissolving Buccal Films as Drug Delivery System for Vaccines

Journal of Pharmacy & Pharmaceutical Sciences, 2019
Vaccination is considered one of the most successful public health interventions of the modern era. Vaccines are categorized based on the antigen used, delivery system and the route of administration.
Mohammad Nasir Uddin, Amanda Allon, Monzurul A Roni, Samir Kouzi   +3 more
doaj   +3 more sources

Iontophoresis-Enhanced Buccal Delivery of Cisplatin-Encapsulated Chitosan Nanoparticles for Treating Oral Cancer in a Mouse Model. [PDF]

Int J Nanomedicine
Chen YW, He AC, Huang TY, Lai DH, Wang YP, Liu WW, Kuo WT, Hou HH, Cheng SJ, Lee CY, Chuang WC, Chang CC, Lee BS.   +12 more
europepmc   +2 more sources

Permeability of Buccal Mucosa

Pharmaceutics, 2021
The buccal mucosa provides an alternative route of drug delivery that can be more beneficial compared to other administration routes. Although numerous studies and reviews have been published on buccal drug delivery, an extensive review of the ...
Apipa Wanasathop, Priya B Patel, Hyojin A. Choi, S. Kevin Li   +3 more
doaj   +1 more source

Aerosil in Solid-state Buccal Film for Improved and Sustained Delivery of Valsartan: Molecular Docking Studies [PDF]

Chemical and Biochemical Engineering Quarterly, 2023
To overcome low oral bioavailability and short biological half-life, improved and sustained buccal delivery of valsartan has been proposed. Valsartan film with colloidal silicon dioxide has been prepared using HPMC as mucoadhesive polymer matrix by ...
R. Swain, S. Nandi, P. Bardhan, S. S. Swain, S. Mohapatra, S. Mallick   +5 more
doaj   +1 more source

Development of Imeglimin Electrospun Nanofibers as a Potential Buccal Antidiabetic Therapeutic Approach

Pharmaceutics, 2023
The prevalence of type 2 diabetes (T2D) has been growing worldwide; hence, safe and effective antidiabetics are critically warranted. Recently, imeglimin, a novel tetrahydrotriazene compound, has been approved for use in T2D patients in Japan.
Ali A. Alamer, Nasser B. Alsaleh, Alhassan H. Aodah, Abdullah A. Alshehri, Fahad A. Almughem, Sarah H. Alqahtani, Haya A. Alfassam, Essam A. Tawfik   +7 more
doaj   +1 more source

An Alternative Device for the Topical Treatment of Oral Cancer: Development and Ex-Vivo Evaluation of Imiquimod-Loaded Polysaccharides Formulations

Pharmaceutics, 2022
The topical use of imiquimod (IMQ), a non-specific immune response modifier, showed to be a promising therapeutic option for the early-stage treatment of some type of oral cancer, even when performed with a formulation (Aldara®) developed and approved ...
Paula de Freitas Rosa Remiro, Mariana Harue Taniguchi Nagahara, Martina Ghezzi, Alessia Filippini, Anna Demurtas, Silvia Pescina, Patrizia Santi, Cristina Padula, Ângela Maria Moraes, Sara Nicoli   +9 more
doaj   +1 more source