Results 151 to 160 of about 2,886,007 (195)
Current status and the future of buccal drug delivery systems
Expert Opinion on Drug Delivery, 2008 Background : The delivery of drugs through the buccal mucosa has received a great deal of attention over the last two decades, and yet there are not many buccal delivery products available on the market.
sevda Senel, Michael J Rathbone
exaly +2 more sources
Current Status of Mucoadhesive Gel Systems for Buccal Drug Delivery
Current Pharmaceutical Design, 2021 Background: Buccal drug delivery is a fascinating research field. Gel-based formulations present potent characteristics as buccal systems since they have great physicochemical properties.
Ayse Pinar Yağcılar +2 more
exaly +2 more sources
Some of the next articles are maybe not open access.
Related searches:
Related searches:
Advances in Buccal Drug Delivery
Critical Reviews in Therapeutic Drug Carrier Systems, 2005The buccal route offers an attractive alternative for systemic drug delivery of drugs because of better patient compliance, ease of dosage form removal in emergencies, robustness, and good accessibility. Use of buccal mucosa for drug absorption was first attempted by Sobrero in 1847, and since then much research was done to deliver drugs through this ...
Raj, Birudaraj +3 more
openaire +2 more sources
Drug Development and Industrial Pharmacy, 1995
AbstractBuccal administration offers certain unique advantages for the drugs which cannot be easily or efficiently administered by oral or intravenous route. However, transbucccal delivery receiived relatively little attention and few well-controlled studies of buccal mucosa permeability have been conducted.
N. Chidambaram, A. K. Srivatsava
openaire +1 more source
AbstractBuccal administration offers certain unique advantages for the drugs which cannot be easily or efficiently administered by oral or intravenous route. However, transbucccal delivery receiived relatively little attention and few well-controlled studies of buccal mucosa permeability have been conducted.
N. Chidambaram, A. K. Srivatsava
openaire +1 more source
2011
The buccal cavity can be most useful for delivery of drugs for systemic effects. Advantages can include rapid onset of action, avoidance of presystemic elimination, which may include gastrointestinal degradation, first-pass clearance by the liver, or transformation by intestinal mucosal enzymes, e.g., CYP450.
Michael A. Repka +2 more
openaire +1 more source
The buccal cavity can be most useful for delivery of drugs for systemic effects. Advantages can include rapid onset of action, avoidance of presystemic elimination, which may include gastrointestinal degradation, first-pass clearance by the liver, or transformation by intestinal mucosal enzymes, e.g., CYP450.
Michael A. Repka +2 more
openaire +1 more source
Expert Opinion on Drug Delivery, 2005
Buccal formulations have been developed to allow prolonged localised therapy and enhanced systemic delivery. The buccal mucosa, however, while avoiding first-pass effects, is a formidable barrier to drug absorption, especially for biopharmaceutical products (proteins and oligonucleotides) arising from the recent advances in genomics and proteomics. The
openaire +2 more sources
Buccal formulations have been developed to allow prolonged localised therapy and enhanced systemic delivery. The buccal mucosa, however, while avoiding first-pass effects, is a formidable barrier to drug absorption, especially for biopharmaceutical products (proteins and oligonucleotides) arising from the recent advances in genomics and proteomics. The
openaire +2 more sources
Buccal delivery for peptide drugs
Journal of Controlled Release, 1992Abstract The non-parenteral delivery of peptides via mucosal routes is essential for the enlargement of the therapeutic benefit of various oligopeptides. Among the routes under discussion the buccal mucosa was found to allow permeation of therapeutically relevant doses, e.g.
Hans P. Merkle, Gregor Wolany
openaire +1 more source
Evaluation of polymeric films for buccal drug delivery
Die Pharmazie, 2009The objective of this study was to evaluate the suitability of the bioadhesive polymers Carbopol 981 NF, Carbopol 1382 and sodium alginate as possible carriers for films for buccal drug delivery. Films were prepared by casting and solvent evaporation method, using propylene glycol as plasticizer and hydoxypropylmethyl cellulose to modify the properties
S, Skulason +3 more
openaire +2 more sources
Buccal Drug Delivery System-A Novel Drug Delivery System
Research Journal of Science and Technology, 2016Buccal delivery is defined as drug administration through the mucosal membranes lining the cheeks (buccal mucosa). The main impediment to the use of many hydrophilic macromolecular drugs as potential therapeutic agents is their inadequate and erratic oral absorption.
Debjit Bhowmik +2 more
openaire +1 more source