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A Review on Mucoadhesive Buccal Drug Delivery
Research Journal of Science and Technology, 2023The discovery and development of medical formulations is presently concentrated on the improvement of therapeutic drugs to be aimed at the targeted location or place to reduce total dissemination in the host. The Mucoadhesive drug delivery system is most potential therapeutic agent. The buccal route is a best route from all dosages form. In this review
Jyoti Dattatray Anap +2 more
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Drug Delivery Approaches for Buccal and Sublingual Administration
Drug ResearchAbstractBoth local and systemic medication delivery benefit greatly from the sublingual and buccal modes of administration. They have shown to be a successful substitute for the conventional oral route, particularly in situations requiring a quick commencement of action. Via venous drainage to
Asad, Ahmad +4 more
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Drug delivery via the buccal mucosa
Pharmaceutical Science & Technology Today, 1998Abstract A candidate drug has entered the development phase but there are problems in drug delivery. The oral bioavailability is low or provides the wrong plasma profile. It is usual that other routes of administration are proposed such as nasal, pulmonary, transdermal, buccal or rectal drug delivery.
Janet A.J Hoogstraate +2 more
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Buccal/gingival drug delivery systems
Journal of Controlled Release, 1987Abstract As a continuation of our previous work on oral mucosal adhesive tablets for the administration of insulin and for treatment of aphtous stomatitis, we have investigated a similar type of dosage form using hydroxypropyl cellulose, Carbopol and lidocaine of a model drug for the treatment of toothache by applying the system to the human gingiva.
Tsuneji Nagai, Ryoji Konishi
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Developments in buccal drug delivery.
Critical reviews in therapeutic drug carrier systems, 1991The buccal mucosa offers excellent possibilities for the (long-term) delivery of suitable drugs, especially for metabolically unstable drugs, such as peptides. A review is given of the present knowledge about buccal drug absorption and drug delivery devices.
M E, de Vries +3 more
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Drug Delivery of Peptides: The Buccal Route
1986Peptides and proteins are currently emerging as a major class of future drugs. So far the research in this field is mainly focused on basic research covering isolation, synthesis, analysis, and biological and clinical effects. However, increasing attention is now also given to considerations regarding suitable dosage forms and routes of absorption.
Hans P. Merkle +3 more
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An Overview on Buccal Drug Delivery System
SunText Review of Pharmaceutical Sciences, 2021Mubarak ZO, Hameed F
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ADVANCE IN BUCCAL MUCOADHESIVE DRUG DELIVERY
Drugs that undergo significant first-pass metabolism and are poorly absorbed or broken down in the gastrointestinal tract can be conveniently administered using buccal mucoadhesive drug administration. These technologies improve bioavailability and patient compliance by sticking to the buccal mucosa and enabling controlled release and direct medicationnull Pratiksha S. Teli +5 more
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Significant biopolymers and their applications in buccal mediated drug delivery
Journal of Biomaterials Science, Polymer Edition, 2021Awanish Kumar, Rajat Anand
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