Results 51 to 60 of about 586,068 (309)
Next generation therapeutics for Alzheimer's disease
EMBO Molecular Medicine, 2013 To date, no truly effective therapy has been developed for Alzheimer's disease or mild cognitive impairment. In searching for new approaches that may succeed where previous ones have failed, it may be instructive to consider the successful therapeutic ...
Dale E. Bredesen, Varghese John
doaj +1 more source
A revision of the genus Potamium (Musci: Sematophyllaceae). [PDF]
, 1992 The neotropical genus Potamium as described by Mitten (1869) included species that had little more in common than a growth form adapted to a semi-aquatic habitat.
Florschütz-de Waard, J.
core
Transforming Grain‐Boundary Brittle Precipitates to Ductility Pathways in Complex Concentrated Alloy
Advanced Science, EarlyView.By engineering graded BCC/L12 interfaces, brittle precipitates in a complex concentrated alloy enable sequential deformation, realizing gigapascal strength with >20% elongation to solve the strength‐ductility trade‐off. ABSTRACT Conventional wisdom holds that hard grain‐boundary (GB) precipitates embrittle structural alloys by acting as crack ...
Zhixin Li +14 more
wiley +1 more source
An Optimal Current Observer for Predictive Current Controlled Buck DC-DC Converters
Sensors, 2014 In digital current mode controlled DC-DC converters, conventional current sensors might not provide isolation at a minimized price, power loss and size.
Run Min +5 more
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The right and the wrong kind of reasons [PDF]
, 2017 In a number of recent philosophical debates, it has become common to distinguish between two kinds of normative reasons, often called the right kind of reasons (henceforth: RKR) and the wrong kind of reasons (henceforth: WKR).
Gertken, Jan, Kiesewetter, Benjamin
core +1 more source
Advanced Science, EarlyView.This study uncovers two overlooked bottlenecks in cryogenic laser cooling of solids: symmetry‐driven fluorescence trapping and water vapor condensation. We demonstrate that breaking sample symmetry enhances fluorescence escape, while condensation dominates parasitic heating below 135 K.
Biao Zhong +5 more
wiley +1 more source
Nature CommunicationsMicrogravity is associated with immunological dysfunction, though the mechanisms are poorly understood. Here, using single-cell analysis of human peripheral blood mononuclear cells (PBMCs) exposed to short term (25 hours) simulated microgravity, we ...
Fei Wu +24 more
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Encoding Cumulation to Learn Perturbative Nonlinear Oscillatory Dynamics
Advanced Science, EarlyView.Weak nonlinearities critically shape the long term behavior of oscillatory systems but are difficult to identify from data. A data‐driven framework is introduced to infer governing equations of weakly nonlinear oscillators from sparse and noisy observations.
Teng Ma +5 more
wiley +1 more source
OXR1 maintains the retromer to delay brain aging under dietary restriction
Nature CommunicationsDietary restriction (DR) delays aging, but the mechanism remains unclear. We identified polymorphisms in mtd, the fly homolog of OXR1, which influenced lifespan and mtd expression in response to DR.
Kenneth A. Wilson +23 more
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Effect of cholesterol supplementation on cryosurvival of goat spermatozoa [PDF]
Veterinary World, 2015 Aim: Sperm membrane cholesterol influences cryodamage during cryopreservation. The present study was carried out to evaluate the effect of varying cholesterol levels in Tris based extenders on the freezability of sexually healthy Malabari buck semen ...
Sunita Behera +3 more
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