Results 41 to 50 of about 40,925 (263)

ChicGrasp: Imitation‐Learning‐Based Customized Dual‐Jaw Gripper Control for Manipulation of Delicate, Irregular Bio‐Products

Advanced Robotics Research, EarlyView.
Automated poultry processing lines still rely on humans to lift slippery, easily bruised carcasses onto a shackle conveyor. Deformability, anatomical variance, and hygiene rules make conventional suction and scripted motions unreliable. We present ChicGrasp, an end‐to‐end hardware‐software co‐designed imitation learning framework, to offer a ...
Amirreza Davar, Zhengtong Xu, Siavash Mahmoudi, Pouya Sohrabipour, Chaitanya Pallerla, Yu She, Wan Shou, Philip Glen Crandall, Dongyi Wang   +8 more
wiley   +1 more source

Systems biology approaches identify metabolic signatures of dietary lifespan and healthspan across species

Nature Communications
Dietary restriction (DR) is a potent method to enhance lifespan and healthspan, but individual responses are influenced by genetic variations. Understanding how metabolism-related genetic differences impact longevity and healthspan are unclear.
Tyler A. U. Hilsabeck, Vikram P. Narayan, Kenneth A. Wilson, Enrique M. Carrera, Daniel Raftery, Daniel Promislow, Rachel B. Brem, Judith Campisi, Pankaj Kapahi   +8 more
doaj   +1 more source

Sites of reactive oxygen species generation by mitochondria oxidizing different substrates

Redox Biology, 2013
Mitochondrial radical production is important in redox signaling, aging and disease, but the relative contributions of different production sites are poorly understood.
Casey L. Quinlan, Irina V. Perevoshchikova, Martin Hey-Mogensen, Adam L. Orr, Martin D. Brand   +4 more
doaj   +1 more source

Metabolomics analysis of buck semen cryopreserved with trehalose

Frontiers in Genetics, 2022
Trehalose is commonly used as an impermeable cryoprotectant for cryopreservation of cells, but its cryoprotective mechanism has now not but been determined.
Bingbing Xu, Bingbing Xu, Bingbing Xu, Zhiying Wang, Zhiying Wang, Zhiying Wang, Ruijun Wang, Ruijun Wang, Ruijun Wang, Guoxin Song, Guoxin Song, Guoxin Song, Yanjun Zhang, Yanjun Zhang, Yanjun Zhang, Rui Su, Rui Su, Rui Su, Yongbin Liu, Jinquan Li, Jinquan Li, Jinquan Li, Jiaxin Zhang, Jiaxin Zhang, Jiaxin Zhang   +24 more
doaj   +1 more source

Two Routes to Land: Genomic Underpinnings of Parallel Aerial Egg Deposition in Aquatic Old‐World Pila and New‐World Pomacea (Ampullariidae)

Advanced Science, EarlyView.
Comparative genomics of Gondwana‐diverged Pila and Pomacea reveals parallel evolution of aerial oviposition. Convergent chromosomal rearrangements reshape regulatory landscapes within topologically associating domains. Lineage‐specific gene family expansions and viral‐derived perivitelline proteins (PV1) underpin desiccation resistance.
Yufei Zhou, Huawei Mu, Xueying Nie, Yue Gao, Hui Wang, Ling Fang, Tiangang Luan, Monthon Ganmanee, Jian‐Wen Qiu, Jin Sun, Jack Chi‐Ho Ip   +10 more
wiley   +1 more source

Next generation therapeutics for Alzheimer's disease

EMBO Molecular Medicine, 2013
To date, no truly effective therapy has been developed for Alzheimer's disease or mild cognitive impairment. In searching for new approaches that may succeed where previous ones have failed, it may be instructive to consider the successful therapeutic ...
Dale E. Bredesen, Varghese John
doaj   +1 more source

The use of site-specific suppressors to measure the relative contributions of different mitochondrial sites to skeletal muscle superoxide and hydrogen peroxide production

Redox Biology, 2020
Reactive oxygen species are important signaling molecules crucial for muscle differentiation and adaptation to exercise. However, their uncontrolled generation is associated with an array of pathological conditions.
Renata L.S. Goncalves, Mark A. Watson, Hoi-Shan Wong, Adam L. Orr, Martin D. Brand   +4 more
doaj   +1 more source

A Triple‐Nanoparticle System for Controlled Graphene Nanosheet Stacking: Enabling K/Na‐Ion Battery Anodes with Ultra‐Fast Charging Exceeding Petroleum Vehicle Refueling

Advanced Science, EarlyView.
ABSTRACT Large‐ion (K, Na) battery systems mitigate uneven global lithium distribution, while their ability to attain recharge time shorter than refueling would remove the final barrier for secondary batteries to replace petroleum vehicles. However, their large‐ion chemistry makes ultra‐fast charging an even significant challenge.
Shukai Ding, Le Zhang, Hang Li, Yang Zhang, Guoquan Suo, Bin Han, Dongfeng Sun, Wenqi Zhao, Gaohui Du, Qingmei Su, Bingshe Xu, Zhen Xu, Wei Wang   +12 more
wiley   +1 more source

A Portable and Dual‐Button Microneedle Device Enables Intelligent Multimodal Laser Sensing

Advanced Science, EarlyView.
A portable and dual‐button microneedle device enables rapid interstitial fluid sampling. Coupled with multimodal laser sensing and AI‐assisted data processing, the platform enables simultaneous molecular and elemental analysis for minimally invasive and multiplexed health assessment toward point‐of‐care diagnostics.
Yuanchao Liu, Xiujuan Hu, Shengqun Shi, Bowen Li, Zhixing Ge, Yunchen Long, Chaochao Sun, Annan Chen, Bingbing Gao, Lianbo Guo, Condon Lau, Wei Luo, Chwee Teck Lim   +12 more
wiley   +1 more source

Lifespan-increasing drug nordihydroguaiaretic acid inhibits p300 and activates autophagy

npj Aging and Mechanisms of Disease, 2019
Aging is characterized by the progressive loss of physiological function in all organisms. Remarkably, the aging process can be modulated by environmental modifications, including diet and small molecules.
Tugsan Tezil, Manish Chamoli, Che-Ping Ng, Roman P. Simon, Victoria J. Butler, Manfred Jung, Julie Andersen, Aimee W. Kao, Eric Verdin   +8 more
doaj   +1 more source