Results 111 to 120 of about 1,541,952 (310)

The national budget impact of managed entry agreement strategies match with high-cost drugs to maximise drug cost saving: a study protocol

Journal of Pharmaceutical Policy and Practice
Background Drug expenditure is an important part of health expenditure. Managed Entry Agreement (MEA) is a common strategy implemented in many countries, such as the United States, the United Kingdom, and the European countries to control drug ...
Piyapat Owat, Chaoncin Sooksriwong, Hataiwan Ratanabunjerdkul, Tuangrat Phodha   +3 more
doaj   +1 more source

Investment decisions and the soft budget constraint: evidence from Hungarian manufacturing firms [PDF]

This paper investigates the investment behaviour of a large panel of Hungarian firms in the period 1989–99, in order to assess the impact of institutional and regulatory changes on the efficiency of credit allocation.
Colombo, Emilio, Stanca, Luca
core   +1 more source

A Soft Matrix Microenvironment Promotes Laterally Spreading Tumors via Oxidative Phosphorylation‐Dependent Cell Adhesion

Advanced Science, EarlyView.
Laterally spreading tumors (LSTs) are precancerous colorectal lesions characterized by a flat morphology. This study reveals a mechanochemical pathway through which a soft matrix microenvironment diminishes spatial constraints in intestinal adenomas. This process promotes deficiencies in tight junction proteins, mediated by the mechanoreceptor ADORA2B ...
Jiamin Zhong, Jingyi Lu, Haopeng Li, Jun Zhong, Xiaobei Luo, Yiyi Hu, Xianfei Wang, Pengfei Wang, Yanning Zhang, Zhenjiang Wang, Qiuhua Lai, Zhenyu Chen, Wenting Mi, Wang Tin San‐to, Weize Li, Shuping Tan, Qihong Cheng, Ruijia Li, Yida Nie, Side Liu, Bing Huang, Zelong Han   +21 more
wiley   +1 more source

More for the poor is less for the poor : the politics of targeting [PDF]

Standard economic analyses suggests that when the budget for redistribution is fixed, transfers should be targeted to (that is, means-tested for) those most in need.
Gelbach, Jonath B., Pritchett, Lant H.
core  

INB3P: A Multi‐Modal and Interpretable Co‐Attention Framework Integrating Property‐Aware Explanations and Memory‐Bank Contrastive Fusion for Blood–Brain Barrier Penetrating Peptide Discovery

Advanced Science, EarlyView.
INB3P is a multimodal framework for blood–brain barrier‐penetrating peptide prediction under extreme data scarcity and class imbalance. By combining physicochemical‐guided augmentation, sequence–structure co‐attention, and imbalance‐aware optimization, it improves predictive performance and interpretability.
Jingwei Lv, Qianyang Wu, Jian Liu, Binlu Yang, Yuanhao Li, Junlin Xu, Yajie Meng, Leyi Wei, Zilong Zhang, Quan Zou, Xiulai Li, Feifei Cui   +11 more
wiley   +1 more source

The Impact on Maine's Budget of Allowing Same-Sex Couples to Marry [PDF]

, 2009
This analysis estimates the impact of allowing same-sex couples to marry on Maine's state budget. We estimate that allowing same-sex couples to marry will result in a net gain of approximately $7.9 million each year for the State. This net impact will be
Brad Sears, Christopher Ramos, M. V. Lee Badgett, Michael D. Steinberger   +3 more
core   +1 more source

Budget impact projecties voor geneesmiddelen

Vandaag worden de toekomstige uitgaven voor geneesmiddelen vooral voorspeld op basis van uitgaven en trends uit het verleden. Dit volstaat echter niet om de impact van dure, opkomende geneesmiddelen, zoals cel- en gentherapieën, in te schatten. Om ze te identificeren en het systeem voor te bereiden op hun komst, moet de farmaceutische pijplijn ...
Odnoletkova, Irina, Reynders, Dries, De Keersmaeker, Frederik, Devriese, Stephan, Goetghebeur, Els, Cleemput, Irina   +5 more
openaire   +1 more source

Ethical Precision in Nanoscale Brain Interfacing

Advanced Science, EarlyView.
As brain interfaces approach the nanoscale, precision no longer only measures—it knows, predicts, and potentially reshapes the mind. This work argues that traditional ethics fails under such conditions and proposes a shift toward continuous, operation‐based governance using the recovery–discovery framework to track, constrain, and responsibly steer ...
Guilherme Wood
wiley   +1 more source

Investigating the Cyclical Behavior of Fiscal Policy in the Republic of Macedonia during the Period of Transition [PDF]

The main aim of this research is to investigate the cyclical behavior of fiscal policy with respect to output gap fluctuations in the Republic of Macedonia during the period 1991-2009.
Ana Mitreska, Anita Angelovska Bezovska, Jane Bogoev, Maja Kadievska Vojnovik   +3 more
core   +1 more source

The Budget Control Act of 2011: Impact on Public Services in Ohio [PDF]

, 2012
Outlines how reduced federal support for states between 2012 and 2021 will affect Ohio's public services, including K-12 education, work study and aid for low-income college students, health and human services, food aid, and housing and urban ...
Wendy Patton
core