Results 151 to 160 of about 3,231 (233)

3α-Hydroxybufadienolides in Bufo gallbladders: structural insights and biotransformation. [PDF]

Nat Prod Bioprospect
Ruan LJ, Song ZJ, Jiang RW.
europepmc   +1 more source

Antimalarial efficacy of <i>Duttaphrynus melanostictus</i> skin extract via inhibition of <i>Plasmodium falciparum</i> Na⁺/H⁺ ATPase. [PDF]

J Parasit Dis
Bagwe AD, D'Souza RC, Sharma BB.
europepmc   +1 more source

Estrone-α-2-Deoxy-Glucoside as a Targeted Therapy for Triple-Negative Breast Cancer: Aromatase Inhibition and Cytotoxicity. [PDF]

Chem Biol Drug Des
Huang TY, Wang MR, Chou FP, Huang SC, Hsiao PY, Wu TK.   +5 more
europepmc   +1 more source

[Biosynthesis of cardenolides and bufadienolides].

Postepy biochemii, 1973
openaire   +1 more source

Isolation, Identification and Chemical Modification of Bufadienolides from Bufo melanostictus Schneider and Their Cytotoxic Activities against Prostate Cancer Cells. [PDF]

Molecules
Ye Q, Lin R, Chen Z, Li J, Zheng C.
europepmc   +1 more source

Isoginkgetin Induces Caspase Cascade Activation and Cell Apoptosis via JNK Signaling in Oral Cancer. [PDF]

J Cancer
Yang WE, Chuang CY, Lin CW, Su CW, Tsai MY, Su SC, Wu HH, Yang SF, Chen YT.   +8 more
europepmc   +1 more source

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Bufadienolide glycosides and bufadienolides from the whole plants of Helleborus lividus, and their cytotoxic activity

Phytochemistry, 2020
Cytotoxicity-guided fractionation of the MeOH extract of Helleborus lividus Aiton ex Curtis (Ranunculaceae) resulted in the isolation of five undescribed bufadienolide glycosides and two undescribed bufadienolides, along with three known compounds. Their structures were determined by detailed spectroscopic analysis and hydrolysis studies.
Akihito Yokosuka, Yoshihiro Mimaki, Tomoki IGUCHI   +2 more
exaly   +4 more sources

Cytochrome P450 Mining for Bufadienolide Diversification

ACS Chemical Biology
Bufadienolides are a class of steroids with a distinctive α-pyrone ring at C17, mostly produced by toads and consisting of over 100 orthologues. They exhibit potent cardiotonic and antitumor activities and are active ingredients of the traditional Chinese medicine Chansu and Cinobufacini.
Xiaolai Lei, Xiaozheng Wang, Weiliang Xiong, Han Xiao, Yingchun Wu, Tingting Huang, Rubing Liang, Yiming Li, Shuangjun Lin   +8 more
openaire   +3 more sources

One new bufadienolide from Chinese drug “Chan'Su”

Journal of Asian Natural Products Research, 2008
A new bufadienolide named 16beta-acetoxy-bufarenogin (1), together with six known bufadienolides, namely, 11alpha,12beta-dihydroxy-bufalin (2), bufotalin (3), hellebrigenin (4), desacetylbufotalin (5), gamabufotalin (6), and resibufagin (7) were isolated from Chan'Su. Of these, 2 was a new natural product.
Li, Qiao, Yong-Fu, Huang, Jia-Qing, Cao, Yu-Zhi, Zhou, Xiu-Lan, Qi, Yue-Hu, Pei   +5 more
exaly   +3 more sources

The Potential Mechanism of Bufadienolide-Like Chemicals on Breast Cancer via Bioinformatics Analysis

Cancers, 2019
Bufadienolide-like chemicals are mostly composed of the active ingredient of Chansu and they have anti-inflammatory, tumor-suppressing, and anti-pain activities; however, their mechanism is unclear.
Ying-Bo Zhang, Chao Yuan, Qu Liping
exaly   +2 more sources