Results 171 to 180 of about 3,231 (233)

Arenobufagin, a natural bufadienolide from toad venom, induces apoptosis and autophagy in human hepatocellular carcinoma cells through inhibition of PI3K/Akt/mTOR pathway

Carcinogenesis, 2013
Dong-Mei Zhang, Jun-shan Liu, Hai-yan Tian   +2 more
exaly   +2 more sources

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Bufadienolides from Urginea maritima from Egypt

Phytochemistry, 1996
Forty-one bufadienolides were isolated from the bulbs of Urginea maritima agg. from Egypt; 26 of them are new natural compounds. Structure elucidation was performed by comparison with authentic substances or by means of 1H, 13C NMR and FAB mass spectroscopy.
B, Kopp, L, Krenn, M, Draxler, A, Hoyer, R, Terkola, P, Vallaster, W, Robien   +6 more
openaire   +2 more sources

Isolation of a novel bufadienolide, bufovende A, and seven known analogs from Venenum bufonis with inhibitory activity on hepatic stellate cell activation.

Natural Product Research
As the principal bioactive constituents of Venenum Bufonis (VB), bufadienolides mediate the therapeutic efficacy of this traditional Chinese medicine in diverse clinical applications.
Huijing Lv, Chengjin Li, Qinggui Li, Qingqing Luo, Yunsong Chen, Anli Liu, Xinyi Du, Qian Cao, Pengwei Zhang, Lingjie Meng   +9 more
semanticscholar   +1 more source

Bufadienolides from Urginea hesperia.

Planta medica, 2013
For the first time the composition of the bufadienolide complex in URGINEA HESPERIA Webb & Berth. has been investigated. From an extract of lyophilized plants, thirteen bufadienolides were isolated. By means of FAB-MS, (1)H-NMR, and (13)C-NMR studies the compounds were structurally elucidated as scillarenin, scilliphaeosidin, scillarenin-3- O-alpha- L ...
L, Krenn, M, Jambrits, B, Kopp
openaire   +4 more sources

Multi-omics reveals bufadienolide Q-markers of Bufonis Venenum based on antitumor activity and cardiovascular toxicity in zebrafish.

Phytomedicine
BACKGROUND Bufonis Venenum (BV) is a traditional animal-based Chinese medicine with therapeutic effects against cancer. However, its clinical use is significantly restricted due to associated cardiovascular risks.
Bo Sun, Nan Si, Xiao-lu Wei, Huijun Wang, Hongjie Wang, Yuyang Liu, Shan Jiang, Huining Liu, Jiaying Yang, Bo Xia, Lihua Chen, B. Bian, Haiyu Zhao   +12 more
semanticscholar   +1 more source

Bufadienolide-Fatty Acid Conjugates from the Fertilized Eggs of Toad Bufo gargarizans: Isolation, Characterization, Toxicity, and Antiproliferative Evaluation.

Journal of Agricultural and Food Chemistry
Bufadienolides (BDs) are a class of naturally occurring toxins present in amphibian toads. Serving as the chemical weapons, they exist not only in the adult toads but also in toad eggs.
Zeping Chen, Qiuchun Yu, Ju Chen, Xiuwen Yu, Jiaqing Cao, Yujia Zhai, Ying Tan, Zhaochun Zhan, Wei Li, Xiaoyan Zou, Xiaoxin Guo, Jiaming Xie, Weihuan Huang, Zhang Zhang, Haiyan Tian   +14 more
semanticscholar   +1 more source

A bufadienolide derived androgen receptor antagonist with inhibitory activities against prostate cancer cells

Chemico-Biological Interactions, 2014
Hai-yan Tian, Lu Jin, Juan Li
exaly   +2 more sources

Binding Efficacy of Bufadienolide a Secondary Metabolite of Bryophyllum pinnatum , Shows its Potential as an Insecticide

New Zealand journal of zoology
Mosquitoes cause several fatal infectious diseases. Synthetic insecticides were effective in the past but had adverse effects on nontarget organisms.
Mathiazhakan Lavanya, Subramanian Monika, K. Selvam, Meena Yadav, M. Shivakumar   +4 more
semanticscholar   +1 more source

A Bufadienolide-Enriched Fraction of Bryophyllum pinnatum Inhibits Human Myometrial Contractility In Vitro

Planta Medica, 2018
Bryophyllum pinnatum has been used since the 1970s to prevent premature labour, first in anthroposophic hospitals and, more recently, also in the main Swiss perinatal centres. However, it is not known which compounds in B.
S. Santos, C. Haslinger, Kristian Klaic, M. Faleschini, M. Mennet, O. Potterat, U. von Mandach, M. Hamburger, A. Simões-Wüst   +8 more
semanticscholar   +1 more source

Cardenolides and Bufadienolide Glycosides from Kalanchoe tubiflora and Evaluation of Cytotoxicity

Planta Medica, 2013
Hui-Chi Huang, Ming-Kuem Lin, Hsin-Ling Yang   +2 more
exaly   +2 more sources