Results 41 to 50 of about 2,339 (195)
Pharmaceutical Biology, 2020 Context Kalanchoe species (Crassulaceae) are widely used in traditional medicine as remedies in infectious diseases and cancer treatment. Objective Cytotoxic and antimicrobial activities of Kalanchoe daigremontiana Raym.-Hamet & H. Perrier, K.
Justyna Stefanowicz-Hajduk +7 more
doaj +1 more source
Angewandte Chemie, Volume 138, Issue 2, 9 January 2026.Twin natural products. This manuscript describes a concise biomimetic synthesis of twin abeo‐steroids bufogargarizins A and B with an unusual [7.5.6.5] and [5.7.6.5] skeletons in 19 steps (LLS). The described synthetic approach features the application of a bioinspired regiodivergent intramolecular aldol addition reaction and a selective singlet oxygen‐
Zoey J. Surma +7 more
wiley +2 more sources
Pharmaceutical Biology, 2021 Context Bufadienolide compounds occur in many plants and animal species and have strong cardiac and anti-inflammatory properties. The compounds have been recently investigated for cytotoxic and antitumor activity.
Justyna Stefanowicz-Hajduk +5 more
doaj +1 more source
Does The Glucocorticoid Stress Response Make Toads More Toxic? An Experimental Study on The Regulation of Bufadienolide Toxin Synthesis [PDF]
, 2023 Chemical defense is a crucial component of fitness in many organisms, yet the physiological regulation of defensive toxin synthesis is poorly understood, especially in vertebrates.
Bókony, Veronika +7 more
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Rhinovirus inhibition by bufadienolides.
Chemical and Pharmaceutical Bulletin, 1988 An evaluation of thirty-four bufadienolides and two related cardenolides against a series of rhinoviruses in vitro has been completed. Most of the bufadienolides were found to display some inhibitory activity. Scillarenin and 3-O-[N-(tert-butoxycarbonyl)hydrazido]succinylbufalin were found to be the most active with chemotherapeutic indices of 32 and ...
Y, Kamano +4 more
openaire +3 more sources
Molecules, 2019 In order to evaluate the quality of Bufonis Venenum commercial herbs, a three-step qualitative and quantitative research study was performed. Firstly, we tried to identify small molecules and peptides in Bufonis Venenum using pre-fractionation ...
Rongrong He +11 more
doaj +1 more source
In-silico analysis of bufadienolides as potential inhibitors of Trypanosoma nucleoside hydrolase
Chemical Physics Impact, 2023 Trypanosomiasis is one of the neglected tropical diseases which curtails the productivity of the victim and causes mortality in extreme cases. Non-availability of vaccines, low therapeutic index of trypanocidal drugs and development of resistance lead to
Shalaka R. Sawant +6 more
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Phytochemical investigations of three Rhodocodon (Hyacinthaceae Sensu APG II) species [PDF]
, 2017 The genus Rhodocodon (Hyacinthaceae sensu APG II) is endemic to Madagascar and its phytochemistry has not been described previously. The phytochemistry of three species in this genus has been investigated and eight compounds, including three ...
Alaa Alqahtani +11 more
core +2 more sources
Chemical defense of toad tadpoles under risk by four predator species
Ecology and Evolution, 2019 Many organisms use inducible defenses as protection against predators. In animals, inducible defenses may manifest as changes in behavior, morphology, physiology, or life history, and prey species can adjust their defensive responses based on the ...
Bálint Üveges +7 more
doaj +1 more source
Morphological variations in populations of Urginea indica Kunth.Liliaceae. [PDF]
, 2010 An attempt has been made to enquire into the morphological variations which leads to evolutionary divergence of populations of Urginea indica Kunth. In particular, there were considerable morphological variations within the species.
Muniyamma, M. +2 more
core +2 more sources