Results 61 to 70 of about 336,292 (314)
E3S Web of Conferences, 2018 Building energy simulation is an important supporting tool for green building design and building energy consumption assessment, At present, Building energy simulation software can't meet the needs of energy consumption analysis and cabinet level micro ...
Zhang Jun, Li Ri Yi
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Assessment of energy utilization and leakages in buildings with building information model energy
Frontiers of Architectural Research, 2017 Given the ability of building information models (BIM) to serve as a multidisciplinary data repository, this study attempts to explore and exploit the sustainability value of BIM in delivering buildings that require less energy for operations, emit less carbon dioxide, and provide conducive living environments for occupants. This objective was attained
Egwunatum I. Samuel +2 more
openaire +3 more sources
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
, 2013 Trigeneration has long been proposed as a means to improve energy-efficiency for large and medium sized buildings. To curb increasing energy demand in the residential sector, researchers are now focusing their attention on adapting trigeneration to ...
Kelly, N.J., Borg, S.P.
core +1 more source
BuildingsBuilding energy modeling tools play a crucial role in quantifying and understanding the energy performance of buildings. These tools require substantial amounts of data, which can be challenging to obtain and are often associated with significant ...
Sofía Gervaz, Federico Favre
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The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Analysis of Energy Consumption and Economy of Regional Gas Tri-Supply Composite System [PDF]
With the development of Chinese society, there is an increasing demand for emissions reduction and the stable operation of the power grid. Regional comprehensive energy supply systems have entered the public’s view owing to their advantages of ...
Deng, M +13 more
core +1 more source
Solar Heat Gain Simulations for Energy-Efficient Guest Allocation in a Large Hotel Tower in Madrid
BuildingsThe current climate and energy crises demand innovative approaches to operating buildings more sustainably. HVAC systems, which significantly contribute to a building’s energy consumption, have been a major focus of research aimed at improving ...
Iker Landa del Barrio +4 more
doaj +1 more source