Results 81 to 90 of about 132,806 (311)

Rethinking buildings. Should buildings simply be enclosures that house different functions?

open access: yesEmerald Open Research, 2020
This document presents BasES, which is a tool kit disseminated as an open educational resource. BasES is focused on the topic of buildings-as-energy services, promoting the knowledge integration to envisage buildings as components of future distributed renewable and interactive energy systems (DRIs).
Kurul, Esra, Sibilla, Maurizio
openaire   +2 more sources

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Towards 3D Indoor Cadastre Based on Change Detection from Point Clouds

open access: yesRemote Sensing, 2019
3D Cadastre models capture both the complex interrelations between physical objects and their corresponding legal rights, restrictions, and responsibilities.
Mila Koeva   +5 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Resilience-based design of a tall building. Case-study.

open access: yesRevista ALCONPAT
This paper presents the assessment of performance of a case-study tall building in quantitative manner in terms of structural and nonstructural components damage, repair cost and repair time, following methodology mentioned in FEMA P-58, precursor ...
Thaung Htut Aung, Mir Shabir Ali Talpur
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Proximity Effect in Crystalline Framework Materials: Stacking-Induced Functionality in MOFs and COFs

open access: yes, 2019
Metal-organic frameworks (MOFs) and covalent organic frameworks (COFs) consist of molecular building blocks being stitched together by strong bonds. They are well known for their porosity, large surface area, and related properties.
Rosalba, Juarez-Mosqueda   +5 more
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Functionality-based application confinement: parameterised hierarchical application restrictions

open access: yes, 2008
Traditional user-oriented access control models such as Mandatory Access Control (MAC) and Discretionary Access Control (DAC) cannot differentiate between processes acting on behalf of users and those behaving maliciously.
Payne, C., Schreuders, Z.C.
core  

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