Results 91 to 100 of about 902,578 (275)

Driving digital transformation in construction: Strategic insights into building information modelling adoption in developing countries

Project Leadership and Society
The construction industry in developing countries faces significant challenges, including limited resources, infrastructure constraints, and varying levels of technological readiness, which hinder the adoption of Building Information Modelling.
Sonam Rinchen, Saeed Banihashemi, Suhair Alkilani   +2 more
doaj   +1 more source

Critical Success Factors for Building Information Modelling Implementation

Construction Economics and Building, 2018
Adoption of Building Information Modelling (BIM) in the global construction industry is fast growing. This paper expounds the Critical Success Factors (CSFs) for BIM implementation and explore their ranking and underlying relationships.
Ganiyu Amuda-Yusuf
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Innovative Approach to the Configuration of Smart Buildings

In_Bo, 2018
In the construction sector, a strong push for innovation is due to the demand for high quality standards of living that can be related to safety, accessibility, usability, energy efficiency, as well as sustainability in terms of construction and ...
Rossana Paparella, Mauro Caini
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Building information modelling and project information management framework for construction projects

Journal of Civil Engineering and Management, 2019
The study aims to develop an effective BIM-project information management framework (BIM-PIMF) and associated assessment model for construction projects with a view to enhancing the functional management of project information.
Timothy O. Olawumi, Daniel W. M. Chan
doaj   +1 more source

Architectural Information Modelling for Virtual Heritage Application [PDF]

, 2008
In today’s AEC industry (Architecture, Engineering and Construction industry), there has been a vast evolution in the usage of information and communication technology (ICT) for describing and managing construction projects.
De Meyer, RonaldTW018010007763600000-0002-3915-765XF47FBAF0-F0ED-11E1-A9DE-61C894A0A6B4, Ioannides, Marinoseditor, Pauwels, PieterTW010020034098098020001893860000-0001-8020-4609FB3F5EE0-F0ED-11E1-A9DE-61C894A0A6B4, Van Campenhout, JanCA01801000295606F39C52F6-F0ED-11E1-A9DE-61C894A0A6B4, Verstraeten, RubenTW01001991317343801001781120F6E01182-F0ED-11E1-A9DE-61C894A0A6B4   +4 more
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Towards the cognitive building: information modeling for the energy audit

Tema, 2018
The new paradigm of smart building requires the accomplishment of occupants needs through the analysis of data gathered within the building, which switches from activities host to provider of customized services for occupants. The digitalization supports
Giuseppe Martino Di Giuda, Emanuela Quaquero, Lavinia C. Tagliabue, Giuseppe Desogus, Antonello Sanna, Angelo L. C. Ciribini   +5 more
doaj   +1 more source

A software vision to enable the holistic design of low carbon buildings [PDF]

, 2011
The need to reduce the energy used by buildings and the resultant carbon emissions is changing how they are designed, look and work. This position paper outlines the urgent need for new software that integrates thermal simulation with building ...
Hetherington, Robina, Laney, Robin, Peake, Stephen   +2 more
core