Results 101 to 110 of about 902,578 (275)

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

A bibliometric analysis of building information modelling implementation barriers in the developing world using an interpretive structural modelling approach. [PDF]

Heliyon, 2023
Takyi-Annan GE, Zhang H.
europepmc   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Hybrid Revit and a new MCDM approach of energy effective nursing-home designed by natural stone and green insulation materials

Journal of Civil Engineering and Management
The requisition for maintainable constructions has been greatly raising over the last several years. To fulfil the maintainability necessities of a construction, decisions or changes must be done to a construction in the course of the preconstruction ...
Figen Balo, Alptekin Ulutaş, Željko Stević, Hazal Boydak, Edmundas Kazimieras Zavadskas   +4 more
doaj   +1 more source

Performance Predictions of Dry and Wet Vapors Ejectors Over Entire Operational Range

Energies, 2017
If a traditional ideal-gas ejector model is used to evaluate the performance of a wet vapor ejector, large deviations from the experimental results will be unavoidable.
Fenglei Li, Zhao Chang, Qi Tian, Changzhi Wu, Xiangyu Wang   +4 more
doaj   +1 more source

Monitoring and Assessment of Indoor Environmental Conditions in Educational Building Using Building Information Modelling Methodology. [PDF]

Int J Environ Res Public Health, 2022
Aguilar AJ, de la Hoz-Torres ML, Ruiz DP, Martínez-Aires MD.   +3 more
europepmc   +1 more source

Building information modelling for visualisation in AEC education [PDF]

, 2005
This paper outlines the process used to introduce building information modelling into the academic curriculum of built environment students and reflects on the techniques used to ensure appropriate use of parametric tools for the purposes of ...
Horne, Margaret, Johansson, Mikael, Roupe, Mattias   +2 more
core   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Impacts of building information modelling (BIM) on communication network of the construction project: A social capital perspective. [PDF]

PLoS One, 2022
Huang Y, Wu L, Chen J, Lu H, Xiang J.
europepmc   +1 more source