Results 81 to 90 of about 902,578 (275)

Geospatial Narratives and their Spatio-Temporal Dynamics: Commonsense Reasoning for High-level Analyses in Geographic Information Systems

open access: yes, 2013
The modelling, analysis, and visualisation of dynamic geospatial phenomena has been identified as a key developmental challenge for next-generation Geographic Information Systems (GIS).
Bhatt, Mehul, Wallgruen, Jan Oliver
core   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Lean construction, building information modelling and sustainability [PDF]

open access: yes
This paper investigates the mutual relations of three current drivers of construction: lean construction, building information modelling and sustainability.
Dave, Bhargav, Koskela, Lauri, Owen, Bob
core  

Sustainable facilities management through building information modelling [PDF]

open access: yes, 2014
Building Information Modelling (BIM) is an approach to improving the efficiency of the building process and potentially providing the key data set needed by facilities managers to operate buildings in a more sustainable manner.
Carbonari, Giulia, Jones, Keith
core  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Building Information Modelling: Present realities and Future possibilities

open access: yesInternational Journal of Engineering and Management Sciences, 2018
BIM (Building Information Modelling), a term that is drawing the attention worldwide in the construction industry and governments, is a complex concept that involves management effort, tools and applications for enhancing information flow and therefore ...
Sergey Pogorelskiy, Diego Alava
doaj   +1 more source

Extension of Petri Nets by Aspects to Apply the Model Driven Architecture Approach [PDF]

open access: yes, 2005
Within MDA models are usually created in the UML. However, one may prefer to\ud use different notations such as Petri-nets, for example, for modelling concurrency\ud and synchronization properties of systems. This paper claims that techniques that\ud are
Aksit, M., Roubtsova, E.E.
core   +1 more source

Advanced Exergy Analysis in the Dynamic Framework for Assessing Building Thermal Systems [PDF]

open access: yes, 2019
This work applies the Dynamic Advanced Exergy Analysis (DAEA) to a heating and domestic hot water (DHW) facility supplied by a Stirling engine and a condensing boiler. For the first time, an advanced exergy analysis using dynamic conditions is applied to
Picallo-Perez, Ana   +3 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy