Results 81 to 90 of about 901,725 (258)

Extension of Petri Nets by Aspects to Apply the Model Driven Architecture Approach [PDF]

open access: yes, 2005
Within MDA models are usually created in the UML. However, one may prefer to\ud use different notations such as Petri-nets, for example, for modelling concurrency\ud and synchronization properties of systems. This paper claims that techniques that\ud are
Aksit, M., Roubtsova, E.E.
core   +1 more source

Geospatial Narratives and their Spatio-Temporal Dynamics: Commonsense Reasoning for High-level Analyses in Geographic Information Systems

open access: yes, 2013
The modelling, analysis, and visualisation of dynamic geospatial phenomena has been identified as a key developmental challenge for next-generation Geographic Information Systems (GIS).
Bhatt, Mehul, Wallgruen, Jan Oliver
core   +2 more sources

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Sustainable facilities management through building information modelling [PDF]

open access: yes, 2014
Building Information Modelling (BIM) is an approach to improving the efficiency of the building process and potentially providing the key data set needed by facilities managers to operate buildings in a more sustainable manner.
Carbonari, Giulia, Jones, Keith
core  

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Lean construction, building information modelling and sustainability [PDF]

open access: yes
This paper investigates the mutual relations of three current drivers of construction: lean construction, building information modelling and sustainability.
Dave, Bhargav, Koskela, Lauri, Owen, Bob
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Building Information Modelling: Present realities and Future possibilities

open access: yesInternational Journal of Engineering and Management Sciences, 2018
BIM (Building Information Modelling), a term that is drawing the attention worldwide in the construction industry and governments, is a complex concept that involves management effort, tools and applications for enhancing information flow and therefore ...
Sergey Pogorelskiy, Diego Alava
doaj   +1 more source

Model selection and model averaging on mortality of upper gastrointestinal bleed patients [PDF]

open access: yes, 2018
Model Selection (MS) is known to produce uncertainty into model-building process. Besides that, the process of MS is complex and time consuming. Therefore, Model Averaging (MA) had been proposed as an alternative to overcome the issues.
Abdullah, Noraini   +3 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

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