Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Delivering building simulation information via new communication media [PDF]
, 2007 Often, the goal of understanding how the building works and the impact of design decisions is hampered by limitations in the presentation of performance data.
Clarke, Joseph Andrew +3 more
core +2 more sources
A Strategy to Maximally Utilize Outdoor Air for Indoor Thermal Environment
Energies, 2021 In order to reduce the energy consumption of HVAC systems in buildings, the use of energy-saving solutions is necessary. One of these solutions is ventilation, which is usually used for maintaining acceptable indoor air quality and thermal comfort.
Lei Tang +4 more
doaj +1 more source
Improving energy modeling of large building stock through the development of archetype buildings [PDF]
, 2011 12th Conference of International Building Performance Simulation ...
Ballarini, Ilaria +3 more
core
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
How to Conduct Human-Centric Building Design? A Review of Occupant Modeling Methods and Applications
BuildingsOccupant modeling has emerged as a critical component in human-centric building design and operation, offering detailed insights into energy performance, comfort optimization, and behavior-driven control strategies.
Rui Sun +4 more
doaj +1 more source
Applied Sciences, 2021 Validation of the EBD-SIM (evidence-based design-simulation) framework, a conceptual framework developed to integrate the use of lighting simulation in the EBD process, suggested that EBD’s post-occupancy evaluation (POE) should be conducted more ...
Anahita Davoodi +2 more
doaj +1 more source
A new thermal analysis by numerical simulation to investigate the energy performance of buildings [PDF]
, 2011 12th Conference of International Building Performance Simulation ...
Ballarini, Ilaria, Corrado, Vincenzo
core
Contrasting the capabilities of building energy performance simulation programs [PDF]
, 2008 For the past 50 years, a wide variety of building energy simulation programs have been developed, enhanced and are in use throughout the building energy community.
Crawley, Drury B. +3 more
core +1 more source
Integrated building performance simulation: Progress, prospects and requirements [PDF]
Building and Environment, 2015 This paper is concerned with the role of Building Performance Simulation (BPS) in assisting with the creation of energy efficient habitats. It characterises achievements to date in a non-program-specific manner and in relation to the ultimate goal of providing practitioners with the means to appraise, accurately and rapidly, the multi-variate ...
J.A. Clarke, J.L.M. Hensen
openaire +3 more sources