Results 101 to 110 of about 2,592,786 (293)

Emergence of Microphysical Bulk Viscosity in Binary Neutron Star Postmerger Dynamics

The Astrophysical Journal Letters
In nuclear matter in isolated neutron stars, the flavor content (e.g., proton fraction) is subject to weak interactions, establishing flavor ( β -)equilibrium. However, there can be deviations from this equilibrium during the merger of two neutron stars.
Elias R. Most, Alexander Haber, Steven P. Harris, Ziyuan Zhang, Mark G. Alford, Jorge Noronha   +5 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Bloch-wave interferometry of driven quasiparticles in bulk GaAs

Physical Review B
We report that the polarizations of sidebands emitted from bulk gallium arsenide (GaAs) driven by a strong terahertz (THz) laser while probed with a weak near-infrared laser can be viewed as interferograms from a Michelson-like interferometer for Bloch waves.
Seamus D. O'Hara, Joseph B. Costello, Qile Wu, Ken West, Loren Pfeiffer, Mark S. Sherwin   +5 more
openaire   +2 more sources

Optimizing Deadline-Driven Bulk Data Transfers in Overlay Networks

2009 Proceedings of 18th International Conference on Computer Communications and Networks, 2009
Deadline-driven bulk data transfers frequently occur in overlay networks running data-intensive, dis- tributed workflow applications, such as grid and cloud envi- ronments. What distinguishes such transfers from other In- ternet traffic is that overlay nodes should cooperate towards the common goal of delivering all inter-dependent data timely, rather ...
Andrei Agapi, Sebastien Soudan, Marcelo Pasin, Pascale Vicat-Blanc Primet, Thilo Kielmann   +4 more
openaire   +5 more sources

Performance enhancement techniques for low-voltage bulk-driven circuits [PDF]

, 2019
Supervisor: Shaik Rafi AhamedIn advanced CMOS process, the device performance characteristics gets affected by changes in the number of fingers due to shallow trench isolation effect, which in turn changes the circuit performance.
Veldandi, Harikrishna
core   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Nano-Resolved Current-Induced Insulator-Metal Transition in the Mott Insulator Ca_{2}RuO_{4}

Physical Review X, 2019
The Mott insulator Ca_{2}RuO_{4} is the subject of much recent attention following reports of emergent nonequilibrium steady states driven by applied electric fields or currents.
Jiawei Zhang, Alexander S. McLeod, Qiang Han, Xinzhong Chen, Hans A. Bechtel, Ziheng Yao, S. N. Gilbert Corder, Thomas Ciavatti, Tiger H. Tao, Meigan Aronson, G. L. Carr, Michael C. Martin, Chanchal Sow, Shingo Yonezawa, Fumihiko Nakamura, Ichiro Terasaki, D. N. Basov, Andrew J. Millis, Yoshiteru Maeno, Mengkun Liu   +19 more
doaj   +1 more source