Results 111 to 120 of about 2,592,786 (293)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Observation of current-induced bulk magnetization in elemental tellurium

Nature Communications, 2017
Electrical control of magnetic response in bulk material without electric or magnetic order is rare and potentially attractive for high efficient spintronics.
Tetsuya Furukawa, Yuri Shimokawa, Kaya Kobayashi, Tetsuaki Itou   +3 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

0.5‐V bulk‐driven CMOS operational amplifier

IET Circuits, Devices & Systems, 2013
A new solution for a low‐voltage bulk‐driven CMOS operational amplifier is presented in this study. The amplifier is designed using 50 nm process parameters and optimised for 0.5 V supply voltage. The circuit consumes 100 μW, performing 74 dB open‐loop gain, 59 nV/Hz 1/2 input referred noise ...
openaire   +1 more source

Symmetry-driven bulk-edge correspondence in electron magnetofluids at finite temperature

Physical Review Research
We present a theoretical framework connecting the pseudo-Chern number in momentum space to the spectral flow index in phase space for continuous media, with specific applications to topological Langmuir-cyclotron waves (TLCWs) in magnetized plasmas at ...
Xianhao Rao, Adil Yolbarsop, Hong Li, Wandong Liu   +3 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Modelling Soil Bulk Density using Data-Mining and Expert Knowledge [PDF]

, 2013
Data about the spatial variation of soil attributes is required to address a great number of environmental issues, such as improving water quality, flood mitigation, and determining the effects of the terrestrial carbon cycle. The need for a continuum of
Taalab, Khaled Paul
core   +2 more sources

Středa Formula for Floquet Systems: Topological Invariants and Quantized Anomalies from Cesàro Summation

Physical Review X
The Středa formula establishes a fundamental physical connection between the topological invariants characterizing the bulk of topological matter and the presence of gapless edge modes.
Lucila Peralta Gavensky, Gonzalo Usaj, Nathan Goldman   +2 more
doaj   +1 more source

Thermodynamics of emergent magnetic charge screening in artificial spin ice

Nature Communications, 2016
Inspired by the physics of bulk frustrated materials, arrays of coupled nanomagnets have been widely explored for the study of collective ordering and emergent behaviour.
Alan Farhan, Andreas Scholl, Charlotte F. Petersen, Luca Anghinolfi, Clemens Wuth, Scott Dhuey, Rajesh V. Chopdekar, Paula Mellado, Mikko J. Alava, Sebastiaan van Dijken   +9 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source