Results 191 to 200 of about 2,592,786 (293)

The sigma-enigma. A multistep homology modeling of sigma1 receptors

, 2011
LAURINI, ERIK, POSOCCO, PAOLA, PRICL, SABRINA, Dal Col, V, MAMOLO, MARIA GRAZIA, ZAMPIERI, DANIELE, VIO, LUCIANO   +6 more
core  

Phonon-Driven Tetrahedral Tilts Enable Ultralow Bulk Thermal Expansion and Interstitial Oxide-Ion Migration in Phenacite Solid Electrolytes. [PDF]

Adv Sci (Weinh)
Li X, Liang L, Shi Q, Wang X, Li C, Deng S, He L, Li Q, Lin K, Xing X, Kuang X.   +10 more
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Nanozapped! DNA, siRNA, and their dendritic nanovectors: a combined in silico/in vitro/in vivo approach

, 2011
Smith, Dk, LAURINI, ERIK, POSOCCO, PAOLA, Jones, Sp, PRICL, SABRINA, Peng, L, Liu, Xx, Dal Col, V, Barnard, A   +8 more
core  

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Interfacial Water State Engineering for Photocatalytic Hydrogen Evolution: From Immersed to Nonimmersed Systems. [PDF]

ChemSusChem
Su Q, Wang C, Wei Z, Lan Y, Shangguan W.
europepmc   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Progress and challenges in exploring the pathogenesis of depressive disorders via RNA sequencing. [PDF]

Front Genet
Zhang B, Zheng S, Guo L, Zhao H.
europepmc   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Sn-Driven Grain Boundary Elimination for Single-Crystalline Ni-Rich Cathodes with Superior High-Voltage Stability in Lithium-Ion Batteries. [PDF]

Adv Sci (Weinh)
Xie G, Qian D, Li R, Liu TX, Lu S.
europepmc   +1 more source