Results 11 to 20 of about 12,137 (255)
PLoS ONE, 2017 Mammalian colonic epithelia consist of cells that are capable of both absorbing and secreting Cl-. The present studies employing Ussing chamber technique identified two opposing short-circuit current (Isc) responses to basolateral bumetanide in rat ...
Lieqi Tang +6 more
doaj +2 more sources
Bumetanide for autism: more eye contact, less amygdala activation [PDF]
Scientific Reports, 2018 Nouchine Hadjikhani +2 more
exaly +2 more sources
Evaluation of bumetanide as a potential therapeutic agent for Alzheimer’s disease
Frontiers in Pharmacology, 2023 Therapeutics discovery and development for Alzheimer’s disease (AD) has been an area of intense research to alleviate memory loss and the underlying pathogenic processes.
Ben Boyarko +16 more
doaj +1 more source
Loop diuretics association with Alzheimer’s disease risk
Frontiers in Aging, 2023 Objectives: To investigate whether exposure history to two common loop diuretics, bumetanide and furosemide, affects the risk of developing Alzheimer’s disease (AD) after accounting for socioeconomic status and congestive heart failure.Methods ...
Anna Graber-Naidich +7 more
doaj +1 more source
Inhibition of NKCC1 attenuated hippocampal LTP formation and inhibitory avoidance in rat. [PDF]
PLoS ONE, 2014 The loop diuretic bumetanide (Bumex) is thought to have antiepileptic properties via modulate GABAA mediated signaling through their antagonism of cation-chloride cotransporters.
Meng Chang Ko +5 more
doaj +1 more source
Frontiers in Immunology, 2022 Autism spectrum disorder (ASD) is a prevalent neurodevelopmental disorder with few medication options. Bumetanide, an FDA-approved diuretic, has been proposed as a viable candidate to treat core symptoms of ASD, however, neither the brain region related ...
Hui Lv +10 more
doaj +1 more source
Decreased Immunoreactivities and Functions of the Chloride Transporters, KCC2 and NKCC1, in the Lateral Superior Olive Neurons of Circling Mice [PDF]
Clinical and Experimental Otorhinolaryngology, 2011 ObjectivesWe tested the possibility of differential expression and function of the potassium-chloride (KCC2) and sodium-potassium-2 chloride (NKCC1) co-transporters in the lateral superior olive (LSO) of heterozygous (+/cir) or homozygous (cir/cir) mice ...
Jonu Pradhan +4 more
doaj +1 more source
BUMETANIDE IN AUTISM SPECTRUM DISORDER
Arquivos de Ciências da Saúde da UNIPAR, 2022 Objectives: This study aimed to make a bibliographic update on the already published data on bumetanide, addressing the main information on its use in Autism Spectrum Disorder (ASD).
Lucas da Silva Moreira +1 more
doaj +1 more source
Frontiers in Psychiatry, 2021 Background: The therapeutic effect of bumetanide on autism spectrum disorder (ASD) seems to be controversial. To obtain better evidence on the efficacy of bumetanide, a systematic review and meta-analysis were performed.Methods: Randomized, placebo ...
Tiantian Wang +4 more
doaj +1 more source
Neuronal and astroglial correlates underlying spatiotemporal Intrinsic Optical Signal in the rat hippocampal slice [PDF]
, 2013 Widely used for mapping afferent activated brain areas in vivo, the label-free intrinsic optical signal (IOS) is mainly ascribed to blood volume changes subsequent to glial glutamate uptake.
Héja, László +3 more
core +7 more sources