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Bundibugyo Virus Disease: Diagnostics and Medical Countermeasures for a Neglected Ebolavirus

open access: yesViruses
Bundibugyo virus disease, caused by Bundibugyo virus (Orthoebolavirus bundibugyoense), is a severe human Ebola disease with substantial mortality, unresolved reservoir ecology, limited diagnostic implementation, and no licensed vaccines or therapeutics ...
Katharina Kopp
doaj   +3 more sources

An imported case of Bundibugyo virus infection, France, June 2026 [PDF]

open access: yesEurosurveillance
In June 2026, an intensive care physician deployed in the Democratic Republic of the Congo and previously vaccinated against Ebola virus developed fatigue, nausea and headaches while returning to France. Bundibugyo virus was identified with RT-PCR.
the Ebola Investigation Team
doaj   +3 more sources

Clinical manifestations and case management of Ebola haemorrhagic fever caused by a newly identified virus strain, Bundibugyo, Uganda, 2007-2008. [PDF]

open access: yesPLoS ONE, 2012
A confirmed Ebola haemorrhagic fever (EHF) outbreak in Bundibugyo, Uganda, November 2007-February 2008, was caused by a putative new species (Bundibugyo ebolavirus). It included 93 putative cases, 56 laboratory-confirmed cases, and 37 deaths (CFR = 25%).
Paul Roddy   +11 more
doaj   +4 more sources

Contextual Note on the Ebola Bundibugyo Outbreak in Ituri (2026)

open access: yes
This note provides contextual background on the Ituri province, currently affected by an Ebola Bundibugyo outbreak. The note does not directly address the news and latest developments in the Ebola response, it rather presents the general context in which public health actions are being deployed by drawing on regional expertise and existing academic ...
Villa, Jules   +27 more
core   +8 more sources

The 2026 Bundibugyo virus disease outbreak in the Democratic Republic of the Congo: Virology, epidemiology, continental response, and research priorities [PDF]

open access: yesInfectious Medicine
Bundibugyo ebolavirus (BDBV), a member of the genus Orthoebolavirus , family Filoviridae , is hereafter referred to as Bundibugyo virus, with the associated illness termed Bundibugyo virus disease (BVD).
Yi Zhang   +3 more
doaj   +2 more sources

From reactive trials to regional vaccine sovereignty: a pan-ebolavirus vaccine-readiness framework for East Africa’s Sudan virus and Bundibugyo virus threats [PDF]

open access: yesFrontiers in Public Health
Vaccines have transformed preparedness for Zaire ebolavirus disease, but East Africa still faces recurrent risk from Sudan virus and Bundibugyo virus, for which licensed and routinely deployable vaccines remain unavailable.
Okechukwu Paul-Chima Ugwu   +4 more
doaj   +2 more sources

Bundibugyo virus—perspectives for the current outbreak

open access: yesnpj Viruses
In May 2026 an outbreak of Bundibugyo virus, a close relative of Ebola virus, was detected in the Democratic Republic of the Congo and Uganda. Rapidly increasing case numbers together with the regional circumstances and current lack of licensed ...
Thomas Hoenen
doaj   +2 more sources

Early Action Review of Detection, Notification, and Response Timeliness during Cross-Border Bundibugyo Virus Disease Outbreak, Uganda, 2026 [PDF]

open access: yesEmerging Infectious Diseases
Bundibugyo virus disease (BVD), an Ebola virus species with no licensed vaccine or therapeutic, reemerged in May 2026 as a cross-border outbreak in Uganda and the Democratic Republic of the Congo. During a 2-day workshop, July 8–9, 2026, we conducted an
Joshua Kayiwa   +21 more
doaj   +2 more sources

Aligning Licensure and Recommended Use to Expedite Vaccine Access in Response to the Ongoing Bundibugyo Ebolavirus Epidemic in Central Africa [PDF]

open access: yesViruses
The ongoing Orthoebolavirus bundibugyoense—Bundibugyo virus (BDBV)—epidemic is the worst Ebolavirus outbreak in a decade and is rapidly expanding, with >4600 suspected cases in the Democratic Republic of Congo (DRC) alone.
George L. O’Hara, Sam Halabi
doaj   +2 more sources

Serology and cytokine profiles in patients infected with the newly discovered Bundibugyo ebolavirus [PDF]

open access: yesVirology, 2012
A new species of Ebolavirus, Bundibugyo ebolavirus, was discovered in an outbreak in western Uganda in November 2007. To study the correlation between fatal infection and immune response in Bundibugyo ebolavirus infection, viral antigen, antibodies, and 17 soluble factors important for innate immunity were examined in 44 patient samples.
Gupta, Manisha   +4 more
openaire   +3 more sources

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