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Bundibugyo Virus Disease: Diagnostics and Medical Countermeasures for a Neglected Ebolavirus [PDF]

Viruses
Bundibugyo virus disease, caused by Bundibugyo virus (Orthoebolavirus bundibugyoense), is a severe human Ebola disease with substantial mortality, unresolved reservoir ecology, limited diagnostic implementation, and no licensed vaccines or therapeutics ...
Katharina Kopp
doaj   +4 more sources

Molecular analysis of the 2012 Bundibugyo virus disease outbreak [PDF]

Cell Reports Medicine, 2021
Bundibugyo virus (BDBV) is one of four ebolaviruses known to cause disease in humans. Bundibugyo virus disease (BVD) outbreaks occurred in 2007-2008 in Bundibugyo District, Uganda, and in 2012 in Isiro, Province Orientale, Democratic Republic of the Congo.
Hulseberg, Christine E., Kumar, Raina, Di Paola, Nicholas, Larson, Peter, Nagle, Elyse R., Richardson, Joshua, Hanson, Jarod, Wauquier, Nadia, Fair, Joseph N., Makuwa, Maria, Mulembakani, Prime, Muyembe-Tamfum, Jean-Jacques, Schoepp, Randal J., Sanchez-Lockhart, Mariano, Palacios, Gustavo F., Kuhn, Jens H., Kugelman, Jeffrey R.   +16 more
exaly   +5 more sources

Beyond Ebola Virus in the Largest Documented Bundibugyo Virus Outbreak [PDF]

Viruses
The ongoing Bundibugyo virus disease outbreak in the Democratic Republic of the Congo and Uganda has become the largest documented outbreak caused by this orthoebolavirus and already ranks as the second-largest Ebola disease outbreak recorded in history.
Damian Stodulski, Natalia Lopez-Escobar, Beatriz Cabanillas   +2 more
doaj   +3 more sources

Alert: how do you respond to Bundibugyo virus disease outbreak?

Lire en français Dear Reader, You know that colleagues in the Democratic Republic of the Congo and Uganda are supporting communities hit by a Bundibugyo virus disease (BVD) outbreak. They are taking real risks to work for health. Here are three things you can do today to support them, each in less than three minutes.
  +29 more sources

Whole-Genome Sequencing for High-Consequence Emerging RNA Viruses: Strategy Selection for Bundibugyo Virus Disease Under 2026 Outbreak Constraints [PDF]

Viruses
Whole-genome sequencing (WGS) is central to outbreak response for high-consequence ribonucleic acid (RNA) viruses, but useful genomes depend on workflow design, sample quality, biosafety, diagnostic breadth, infrastructure, and bioinformatics as much as ...
Katharina Kopp
doaj   +3 more sources

Bundibugyo virus detection during an Ebola virus disease outbreak in the democratic Republic of the Congo: an urgent call for action [PDF]

Tropical Medicine and Health
Ebola virus disease continues to pose a major public health threat in the Democratic Republic of the Congo, with outbreaks caused by different Ebola virus species, including Bundibugyo virus.
Christian Tague, Johan Domga, Josias Silatchom Kamgang, Berthol Fotsing Tawe, Hermann Yokolo, Stephane Hans Bateyi   +5 more
doaj   +3 more sources

The 2026 Bundibugyo virus disease outbreak in the Democratic Republic of the Congo: Virology, epidemiology, continental response, and research priorities [PDF]

Infectious Medicine
Bundibugyo ebolavirus (BDBV), a member of the genus Orthoebolavirus , family Filoviridae , is hereafter referred to as Bundibugyo virus, with the associated illness termed Bundibugyo virus disease (BVD).
Yi Zhang, Junkai Ren, Xuejun Ma, Xiaozhou He   +3 more
doaj   +2 more sources

Ferrets Infected with Bundibugyo Virus or Ebola Virus Recapitulate Important Aspects of Human Filovirus Disease [PDF]

Journal of Virology, 2016
ABSTRACT Bundibugyo virus (BDBV) is the etiological agent of a severe hemorrhagic fever in humans with a case-fatality rate ranging from 25 to 36%. Despite having been known to the scientific and medical communities for almost 1 decade, there is a dearth of studies on this pathogen due to the lack of a small animal model ...
Robert, Kozak, Shihua, He, Andrea, Kroeker, Marc-Antoine, de La Vega, Jonathan, Audet, Gary, Wong, Chantel, Urfano, Kym, Antonation, Carissa, Embury-Hyatt, Gary P, Kobinger, Xiangguo, Qiu   +10 more
openaire   +4 more sources

Early Action Review of Detection, Notification, and Response Timeliness during Cross-Border Bundibugyo Virus Disease Outbreak, Uganda, 2026 [PDF]

Emerging Infectious Diseases
Bundibugyo virus disease (BVD), an Ebola virus species with no licensed vaccine or therapeutic, reemerged in May 2026 as a cross-border outbreak in Uganda and the Democratic Republic of the Congo. During a 2-day workshop, July 8–9, 2026, we conducted an
Joshua Kayiwa, Mudarshiru Bbuye, Ritah Atuhaire, Doreen Nyakato, Mathew Tut, Bayad Nozad, Jovan Baryamujura, Bernard Lubwama, Solome Okware, Pamela Kajumba, Grace Akello, Bonny Kintu, Rebecca Kahunde, Dativa Aliddeki, Motuma Guyassa, Lydia Nakiire, Felix Ocom, Paul Mbaka, Peter Elyanu, Allan Muruta, Atek Kagirita, Charles Olaro   +21 more
doaj   +2 more sources

Development and characterization of a recombinant Bundibugyo virus expressing a fluorescent reporter protein [PDF]

Emerging Microbes and Infections
Bundibugyo virus disease (BVD), caused by Bundibugyo virus (BDBV), is associated with substantial morbidity and mortality, with previous outbreaks reporting case fatality rates of 30%–50%. The ongoing BDBV outbreak in the Democratic Republic of the Congo
Shilpi Jain, Éric Bergeron, Mike Flint, Joel M. Montgomery, Christina F. Spiropoulou, César G. Albariño   +5 more
doaj   +2 more sources