The Re-Emergence of Bundibugyo Ebolavirus in Uganda and the Democratic Republic of Congo: Epidemiological Drivers, Response Strategies, and Implications for Global Health Security [PDF]
Infection and Drug ResistanceGerald Olwit,1 Ivy Bochaberi Ombongi,2 Henon Ataryeba,3 Andrea Nantongo,4 Babirye Shamim51Department of Internal Medicine, Kabale University School of Medicine, Kabale, Uganda; 2Department of Internal Medicine, Jomo Kenyatta University of Agriculture and
Olwit G +4 more
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Abstract The 2026 Bundibugyo virus disease (BVD) outbreak in the DRC and Uganda raises urgent questions about the efficacy of existing Ebola virus (EBOV) monoclonal antibodies (mAbs) against Bundibugyo virus (BDBV). Here, we perform genomic and structural analyses of 44 BDBV sequences, including 12 from the 2026 outbreak, to assess mAb ...
Daudi Jjingo +60 more
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R0 of Bundibugyo virus disease and the critical issue of case ascertainment in the Democratic Republic of the Congo [PDF]
New Microbes and New InfectionsSeiko Fujiwara, Hiroshi Nishiura
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Development and evaluation of a panel of filovirus sequence capture probes for pathogen detection by next-generation sequencing. [PDF]
PLoS ONE, 2014 A detailed understanding of the circulating pathogens in a particular geographic location aids in effectively utilizing targeted, rapid diagnostic assays, thus allowing for appropriate therapeutic and containment procedures.
Jeffrey W Koehler +10 more
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One-Step Reverse-Transcription FRET-PCR for Differential Detection of Five Ebolavirus Species. [PDF]
PLoS ONE, 2015 Ebola is an emerging infectious disease caused by a deadly virus belonging to the family Filoviridae, genus Ebolavirus. Based on their geographical distribution, Ebolavirus has been classified into total five species so far, mainly Zaire, Sudan, Taï ...
Guangwu Lu +6 more
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Regional Initiatives in Support of Surveillance in East Africa: The East Africa Integrated Disease Surveillance Network (EAIDSNet) Experience. [PDF]
, 2013 The East African Integrated Disease Surveillance Network (EAIDSNet) was formed in response to a growing frequency of cross-border malaria outbreaks in the 1990s and a growing recognition that fragmented disease interventions, coupled with weak laboratory
Schneidman, Miriam +13 more
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mBio, 2021 Ebolaviruses Bundibugyo virus (BDBV) and Ebola virus (EBOV) cause fatal hemorrhagic disease in humans and nonhuman primates. While the host response to EBOV is well characterized, less is known about BDBV infection.
Courtney Woolsey +5 more
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Strengthening Ebola virus disease preparedness in Somalia: Lessons from the 2026 Eastern DRC outbreak for early warning and rapid response [PDF]
Journal of Virus EradicationShukri Hassan Mohamed +3 more
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Proportion of Deaths and Clinical Features in Bundibugyo Ebola Virus Infection, Uganda [PDF]
, 2010 The first known Ebola hemorrhagic fever (EHF) outbreak caused by Bundibugyo Ebola virus occurred in Bundibugyo District, Uganda, in 2007. Fifty-six cases of EHF were laboratory confirmed.
Jonathan S. Towner +29 more
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A SOME ECOLOGICAL CHARACTERISTICS OF EBOLA VIRUS IN NATURAL FOCIES
Журнал микробиологии, эпидемиологии и иммунобиологии, 2018 Ebola virus that composed Ebolavirus genus of Filoviridae Family causes severe hemorrhagic fever in humans with high case-fatality rates (up to 90%).
T. E. Sizikova +5 more
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