Results 41 to 50 of about 2,613 (178)

Structural Basis of Pan-Ebolavirus Neutralization by a Human Antibody against a Conserved, yet Cryptic Epitope

open access: yesmBio, 2018
Only one naturally occurring human antibody has been described thus far that is capable of potently neutralizing all five ebolaviruses. Here we present two crystal structures of this rare, pan-ebolavirus neutralizing human antibody in complex with Ebola ...
Brandyn R. West   +6 more
doaj   +1 more source

Public Health Implications of High Cytomegalovirus Seroprevalence in Pregnancy: A Cross‐Sectional Study in Western Uganda

open access: yesPublic Health Challenges, Volume 5, Issue 2, June 2026.
Among immediate postpartum women in western Uganda, maternal CMV seroprevalence was high (81.2%) and was predominantly chronic or non‐primary infection. Older age, rural residence, lower education, and prior spontaneous abortion were associated with seropositivity, supporting targeted maternal CMV education and evaluation of context‐appropriate ...
Bashir Mohamed Naima   +5 more
wiley   +1 more source

Serologic Evidence of Fruit Bat Exposure to Filoviruses, Singapore, 2011–2016

open access: yesEmerging Infectious Diseases, 2018
To determine whether fruit bats in Singapore have been exposed to filoviruses, we screened 409 serum samples from bats of 3 species by using a multiplex assay that detects antibodies against filoviruses.
Eric D. Laing   +14 more
doaj   +1 more source

Antibiotic Susceptibility Profiles and Determinants of Septic Abortion Among Women Admitted for Abortion Care in Ugandan Satellite Teaching Hospitals: A Two‐Center Cross‐Sectional Study

open access: yesHealth Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background and Aims Septic abortion remains a major cause of maternal morbidity and mortality in low‐ and middle‐income countries. This study aimed to determine the prevalence, antibiotic susceptibility profiles, and determinants of septic abortion among women admitted for abortion care in Ugandan satellite teaching hospitals. Methods This two‐
Guled Bashir Gaboose   +5 more
wiley   +1 more source

Clinical history of typhoid fever patients, Kasese and Bundibugyo Districts, April 15, 2011–January 6, 2012.

open access: yes, 2014
†For some items, n may vary by small numbers due to “don't know” responses.*Percentage totals may be >100%; respondents could select ≥1 source of care and antibiotic.‡Kasese patients: 1 school nurse; Bundibugyo patients: 5 friend or relative.‡‡Kasese ...
Janell Routh (531595)   +22 more
core   +1 more source

Cohorts of immature Pteropus bats show interannual variation in Hendra virus serology

open access: yesJournal of Animal Ecology, Volume 95, Issue 3, Page 521-537, March 2026.
Pteropus bat with offspring, photo taken by Manuel Ruiz‐Aravena. Abstract Understanding the drivers of seasonal disease outbreaks remains a fundamental challenge in disease ecology. Periodic outbreaks can be driven by several seasonally varying factors, including pulses of susceptible individuals through births, changes in host behaviour and social ...
Daniel E. Crowley   +24 more
wiley   +1 more source

Bundibugyo ebolavirus qPCR Taqman duplex assay (Bundibugyo + human internal control) v1

open access: yes
In May 2026, an outbreak of Bundibugyo ebolavirus in the Democratic Republic of the Congo was declared a Public Health Emergency of International Concern (PHEIC) by the World Health Organization (WHO), rapidly elevating public health concerns. This has underscored the critical need for reliable diagnostic tools.
Elyse Stachler   +6 more
openaire   +1 more source

Sex Differences in Response to Viral Vector Vaccines—Implications for Future Vaccine Design

open access: yesImmunological Reviews, Volume 338, Issue 1, March 2026.
ABSTRACT Vaccination represents one of the most impactful public health achievements, preventing 3.5 to 5 million deaths annually according to estimates of the World Health Organization. Yet, recent outbreaks of emerging and reemerging infectious diseases highlight the need for rapid and strategic vaccine development using vaccine platforms ...
Ilka Grewe   +2 more
wiley   +1 more source

Bundibugyo ebolavirus outbreaks: update on the current situation

open access: yesRomanian Journal of Infectious Diseases
Bundibugyo ebolavirus, first detected in Uganda in 2007, is the fifth recognized species of ebolavirus and has been associated with several outbreaks in East and Central Africa since then. This virus is genetically distinct, with a reported case fatality rate of 32-34%, and poses major challenges because of its nonspecific clinical features and the ...
Aseer Manilal   +2 more
openaire   +1 more source

In Silico Identification of Antiviral Peptides as Potential Leads Against Sudan Ebolavirus VP‐40

open access: yesBioMed Research International, Volume 2026, Issue 1, 2026.
The continued reemergence of Ebola virus epidemics remains a global health concern, largely due to limited therapeutic interventions. This study is aimed at identifying and characterizing antiviral peptides as potential lead candidates against the Sudan Ebola virus.
Boniface Omara   +13 more
wiley   +1 more source

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