Table S1 Human Outbreaks of Ebola Zaire, Ebola Sudan and Ebola Bundibugyo from 1976 to present
Human Outbreaks of Ebola Zaire, Ebola Sudan and Ebola Bundibugyo from 1976 to ...
Christl A Donnelly (19052) +4 more
core +1 more source
Species breadth is a preparedness metric: lessons from the 2026 Bundibugyo virus disease outbreak
Recent outbreaks of non-Zaire orthoebolaviruses have exposed a persistent weakness in outbreak preparedness: diagnostic, vaccine, therapeutic, regulatory, and research systems remain disproportionately optimized for Ebola virus (EBOV).
Ayan Mohamed Hassan +5 more
doaj +1 more source
Development and evaluation of a panel of filovirus sequence capture probes for pathogen detection by next-generation sequencing. [PDF]
A detailed understanding of the circulating pathogens in a particular geographic location aids in effectively utilizing targeted, rapid diagnostic assays, thus allowing for appropriate therapeutic and containment procedures.
Jeffrey W Koehler +10 more
doaj +1 more source
Background Uganda experiences recurrent Ebola disease (EBOD) outbreaks, yet national suitability maps often pool virus species or are too coarse for district‐level planning. We aimed to generate species‐resolved, 1 km relative environmental suitability surfaces for reported Ebola spillover events in Uganda; quantify the contribution of environmental ...
George Paasi +4 more
wiley +1 more source
Cross-reactive neutralizing human survivor monoclonal antibody BDBV223 targets the ebolavirus stalk
Human antibodies cross-reactive for several viruses within the Ebolavirus genus have been identified. Here the authors present the crystal structure of such a neutralizing monoclonal antibody (mAb) targeting the stalk of Bundibugyo virus glycoprotein and
Liam B. King +11 more
doaj +1 more source
Systematic Review and Meta‐Analysis of Emerging Viral Zoonotic Diseases, 2016–2026
Emerging viral zoonoses—infections caused by viruses that cross the species barrier from animal reservoirs into human populations—account for the majority of emerging infectious disease (EID) events and now constitute a defining threat to global health security.
Pan Tao +5 more
wiley +1 more source
Factors Influencing Exclusive Breastfeeding in Bundibugyo District, Uganda [PDF]
Background: Immediate and exclusive breastfeeding have been recognised by the WHO and UNICEF as important and necessary public health practices that can help prevent child morbidity and mortality, and to satisfy sustainable development goal (SDG) 2.2 ...
Rita Ntegyereize
core +1 more source
Designing and testing broadly-protective filoviral vaccines optimized for cytotoxic T-lymphocyte epitope coverage. [PDF]
We report the rational design and in vivo testing of mosaic proteins for a polyvalent pan-filoviral vaccine using a computational strategy designed for the Human Immunodeficiency Virus type 1 (HIV-1) but also appropriate for Hepatitis C virus (HCV) and ...
Paul W Fenimore +12 more
doaj +1 more source
The Bundibugyo Ebola Virus Emergency and the erosion of global health security [PDF]
Titanji BK.
openaire +2 more sources
DrugBank database is mined to hunt prospective Ebola virus (EBOV) VP35 inhibitors utilizing docking calculations, molecular dynamics, molecular mechanics/generalized Born surface area binding energy calculations, and density functional theory computations.
Alaa H. M. Abdelrahman +5 more
wiley +1 more source

