Results 51 to 60 of about 2,613 (178)

Table S1 Human Outbreaks of Ebola Zaire, Ebola Sudan and Ebola Bundibugyo from 1976 to present

open access: yes, 2015
Human Outbreaks of Ebola Zaire, Ebola Sudan and Ebola Bundibugyo from 1976 to ...
Christl A Donnelly (19052)   +4 more
core   +1 more source

Species breadth is a preparedness metric: lessons from the 2026 Bundibugyo virus disease outbreak

open access: yesEmerging Microbes and Infections
Recent outbreaks of non-Zaire orthoebolaviruses have exposed a persistent weakness in outbreak preparedness: diagnostic, vaccine, therapeutic, regulatory, and research systems remain disproportionately optimized for Ebola virus (EBOV).
Ayan Mohamed Hassan   +5 more
doaj   +1 more source

Development and evaluation of a panel of filovirus sequence capture probes for pathogen detection by next-generation sequencing. [PDF]

open access: yesPLoS ONE, 2014
A detailed understanding of the circulating pathogens in a particular geographic location aids in effectively utilizing targeted, rapid diagnostic assays, thus allowing for appropriate therapeutic and containment procedures.
Jeffrey W Koehler   +10 more
doaj   +1 more source

High‐Resolution Mapping of Environmental Suitability for Reported Ebola Spillover Events in Uganda to Inform Surveillance and Preparedness

open access: yesJournal of Tropical Medicine, Volume 2026, Issue 1, 2026.
Background Uganda experiences recurrent Ebola disease (EBOD) outbreaks, yet national suitability maps often pool virus species or are too coarse for district‐level planning. We aimed to generate species‐resolved, 1 km relative environmental suitability surfaces for reported Ebola spillover events in Uganda; quantify the contribution of environmental ...
George Paasi   +4 more
wiley   +1 more source

Cross-reactive neutralizing human survivor monoclonal antibody BDBV223 targets the ebolavirus stalk

open access: yesNature Communications, 2019
Human antibodies cross-reactive for several viruses within the Ebolavirus genus have been identified. Here the authors present the crystal structure of such a neutralizing monoclonal antibody (mAb) targeting the stalk of Bundibugyo virus glycoprotein and
Liam B. King   +11 more
doaj   +1 more source

Systematic Review and Meta‐Analysis of Emerging Viral Zoonotic Diseases, 2016–2026

open access: yesTransboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Emerging viral zoonoses—infections caused by viruses that cross the species barrier from animal reservoirs into human populations—account for the majority of emerging infectious disease (EID) events and now constitute a defining threat to global health security.
Pan Tao   +5 more
wiley   +1 more source

Factors Influencing Exclusive Breastfeeding in Bundibugyo District, Uganda [PDF]

open access: yes
Background: Immediate and exclusive breastfeeding have been recognised by the WHO and UNICEF as important and necessary public health practices that can help prevent child morbidity and mortality, and to satisfy sustainable development goal (SDG) 2.2 ...
Rita Ntegyereize
core   +1 more source

Designing and testing broadly-protective filoviral vaccines optimized for cytotoxic T-lymphocyte epitope coverage. [PDF]

open access: yesPLoS ONE, 2012
We report the rational design and in vivo testing of mosaic proteins for a polyvalent pan-filoviral vaccine using a computational strategy designed for the Human Immunodeficiency Virus type 1 (HIV-1) but also appropriate for Hepatitis C virus (HCV) and ...
Paul W Fenimore   +12 more
doaj   +1 more source

Drug Repurposing Investigation for Combating Ebola Virus Disease: Database Mining, Docking Calculations, Molecular Dynamics, and Density Functional Theory Study

open access: yesChemistryOpen, Volume 14, Issue 12, December 2025.
DrugBank database is mined to hunt prospective Ebola virus (EBOV) VP35 inhibitors utilizing docking calculations, molecular dynamics, molecular mechanics/generalized Born surface area binding energy calculations, and density functional theory computations.
Alaa H. M. Abdelrahman   +5 more
wiley   +1 more source

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