Results 71 to 80 of about 2,613 (178)

A comprehensive overview on the crosstalk between microRNAs and viral pathogenesis and infection

Medicinal Research Reviews, Volume 45, Issue 2, Page 349-425, March 2025.
Abstract Infections caused by viruses as the smallest infectious agents, pose a major threat to global public health. Viral infections utilize different host mechanisms to facilitate their own propagation and pathogenesis. MicroRNAs (miRNAs), as small noncoding RNA molecules, play important regulatory roles in different diseases, including viral ...
Seyedeh Zahra Bahojb Mahdavi, Asiyeh Jebelli, Parisa Shiri Aghbash, Behzad Baradaran, Mohammad Amini, Fatemeh Oroojalian, Nasser Pouladi, Hossein Bannazadeh Baghi, Miguel de la Guardia, Amir Ali Mokhtarzadeh   +9 more
wiley   +1 more source

Bat-human interactions and associated factors among communities in Bundibugyo District, Uganda: A cross-sectional study.

PLOS Global Public Health
More than 70% of new, emerging, and reemerging infectious diseases are from animal origin. Human interaction with bats has been associated as a driver for various fetal zoonoses, including numerous viral diseases of bat-origin.
James Natweta Baguma, Shamilah Namusisi, Lesley Rose Ninsiima, Rogers Musiitwa, Bridget Nagawa Tamale, Mathius Amperiize, Douglas Bulafu, James Muleme, David Musoke, Clovice Kankya, Charles Drago Kato   +10 more
doaj   +1 more source

Structural Basis of Pan-Ebolavirus Neutralization by an Antibody Targeting the Glycoprotein Fusion Loop

Cell Reports, 2018
Summary: Monoclonal antibodies (mAbs) with pan-ebolavirus cross-reactivity are highly desirable, but development of such mAbs is limited by a lack of a molecular understanding of cross-reactive epitopes.
Charles D. Murin, Jessica F. Bruhn, Zachary A. Bornholdt, Jeffrey Copps, Robyn Stanfield, Andrew B. Ward   +5 more
doaj   +1 more source

Ébola, lo que debemos saber

Revista Ciencias Biomédicas, 2020
La entidad conocida como ébola, recibe esa denominación por el nombre del río más cercano al distrito africano, donde se presentaron los primeros casos del brote en la década de los setenta del siglo XX (1).
Comité Editorial
doaj   +1 more source

Ebolavirus evolution and emergence are associated with land use change

Ecological Monographs, Volume 95, Issue 1, February 2025.
Abstract Anthropogenic land use change facilitates disease emergence by altering the interface between humans and pathogen reservoirs and is hypothesized to drive pathogen evolution. Here, we show a positive association between land use change and the evolution and dispersal of Zaire ebolavirus (EBOV) and Sudan ebolavirus (SUDV).
Christian E. Lange, Thomas R. Barnum, David J. McIver, Matthew LeBreton, Karen Saylors, Charles Kumakamba, Sara Lowes, Eduardo Montero, Robert L. Cohen   +8 more
wiley   +1 more source

Gastrointestinal Parasites of Zoonotic Importance Detected in Bats in the Conservation Area of Semuliki National Park, Western Uganda

Journal of Parasitology Research, Volume 2025, Issue 1, 2025.
Bat guano may contain zoonotic parasites that contaminate the environment and/or serve as a potential source of infection to humans and animals. Repeated bat–human exposure could be a risk factor for zoonosis. To date, knowledge on the status of bat gastrointestinal parasites (GIPs) in Uganda is limited.
James Robert Ochieng, Charles Drago Kato, John Joseph M. Kisakye, Bernard Marchand   +3 more
wiley   +1 more source

Ebola world nightmare from Congo 1976 to Congo again 2026

The Egyptian Journal of Internal Medicine
The ongoing 2026 Bundibugyo virus disease outbreak in the Democratic Republic of the Congo and Uganda has renewed global concern regarding the threat of ebolaviruses. Ebola virus disease is one of the most lethal viral hemorrhagic fevers. Since its first
Amr Saad, Haitham A Hashim
doaj   +1 more source

Mapping the research landscape of antibody therapy for Ebola virus disease: a bibliometric analysis

Frontiers in Immunology
BackgroundAntibody-based therapies have become a cornerstone of Ebola virus disease (EVD) treatment and prevention, particularly following the successful clinical development of monoclonal antibody therapeutics against Zaire ebolavirus.
Zengwei Kou, Zengwei Kou, Yunsheng Liu, Wujie Qian, Sihan Zhang, Shulei Lou, Da Shao   +6 more
doaj   +1 more source

Therapeutic Painting and Sexual Violence Expressed by Students in Selected Secondary Schools in Bundibugyo District in Uganda [PDF]

Sexual violence has often caused distress to many people, and a lot has been written proposing solutions to this vice. Restoring hope among people who have been affected by sexual violence in Secondary schools in Bundibugyo District requires concerted ...
Yiga, Andrew Peters, Julius, Mwijuka, Rebecca, Joyce Bukirwa   +2 more
core   +1 more source

Resilience and residuals beyond containment — The hidden burden of Bundibugyo Ebola virus survivorship sixteen years on: A cross-sectional observational study

New Microbes and New Infections
Background: Long-term effects of Ebola disease (EBOD) are well documented for Ebolavirus (EBOV), but limited data exist for Bundibugyo virus disease (BVD) caused by Bundibugyo Ebola virus (BDBV), a genetically distinct strain.
Raymond Ernest Kaweesa, Joseph Ssebwana Katende, Raymond Reuel Wayesu, Annie Daphine Ntabadde, Solomon Opio, Laban Kato, Gerald Kevin Oluka, Ruth Nambi, Rodney Abraham Tumusiime, Pontiano Kaleebu, Julius Julian Lutwama, Jennifer Serwanga   +11 more
doaj   +1 more source