Results 21 to 30 of about 212 (104)
Tropical Medicine and HealthEbola virus disease continues to pose a major public health threat in the Democratic Republic of the Congo, with outbreaks caused by different Ebola virus species, including Bundibugyo virus.
Christian Tague +5 more
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Can the Ebola Zaire vaccine stop the Bundibugyo virus?
South Sudan Medical JournalReports indicate that the WHO and Africa CDC approved the DRC government’s request to release Ervebo vaccines for use against the Bundibugyo virus in August.
Edward Kenyi
doaj +1 more source
Pathogenicity and Virulence of Ebolaviruses with Species- and Variant-specificity
Virulence, 2021 Ebola virus (EBOV), belonging to the species Zaire ebolavirus in the genus Ebolavirus, causes a severe febrile illness in humans with case fatality rates (CFRs) up to 90%.
Satoko Yamaoka, Hideki Ebihara
doaj +1 more source
Public Health Challenges, Volume 5, Issue 2, June 2026.Among immediate postpartum women in western Uganda, maternal CMV seroprevalence was high (81.2%) and was predominantly chronic or non‐primary infection. Older age, rural residence, lower education, and prior spontaneous abortion were associated with seropositivity, supporting targeted maternal CMV education and evaluation of context‐appropriate ...
Bashir Mohamed Naima +5 more
wiley +1 more source
Beyond Ebola Virus in the Largest Documented Bundibugyo Virus Outbreak
VirusesThe ongoing Bundibugyo virus disease outbreak in the Democratic Republic of the Congo and Uganda has become the largest documented outbreak caused by this orthoebolavirus and already ranks as the second-largest Ebola disease outbreak recorded in history.
Damian Stodulski +2 more
doaj +1 more source
Cell Reports, 2023 Summary: Ebola virus (EBOV) and Bundibugyo virus (BDBV) belong to the family Filoviridae and cause a severe disease in humans. We previously isolated a large panel of monoclonal antibodies from B cells of human survivors from the 2007 Uganda BDBV ...
Rodrigo I. Santos +8 more
doaj +1 more source
Cohorts of immature Pteropus bats show interannual variation in Hendra virus serology
Journal of Animal Ecology, Volume 95, Issue 3, Page 521-537, March 2026.Pteropus bat with offspring, photo taken by Manuel Ruiz‐Aravena. Abstract Understanding the drivers of seasonal disease outbreaks remains a fundamental challenge in disease ecology. Periodic outbreaks can be driven by several seasonally varying factors, including pulses of susceptible individuals through births, changes in host behaviour and social ...
Daniel E. Crowley +24 more
wiley +1 more source
Designing and testing broadly-protective filoviral vaccines optimized for cytotoxic T-lymphocyte epitope coverage. [PDF]
PLoS ONE, 2012 We report the rational design and in vivo testing of mosaic proteins for a polyvalent pan-filoviral vaccine using a computational strategy designed for the Human Immunodeficiency Virus type 1 (HIV-1) but also appropriate for Hepatitis C virus (HCV) and ...
Paul W Fenimore +12 more
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Sex Differences in Response to Viral Vector Vaccines—Implications for Future Vaccine Design
Immunological Reviews, Volume 338, Issue 1, March 2026.ABSTRACT Vaccination represents one of the most impactful public health achievements, preventing 3.5 to 5 million deaths annually according to estimates of the World Health Organization. Yet, recent outbreaks of emerging and reemerging infectious diseases highlight the need for rapid and strategic vaccine development using vaccine platforms ...
Ilka Grewe +2 more
wiley +1 more source
Cross-reactive neutralizing human survivor monoclonal antibody BDBV223 targets the ebolavirus stalk
Nature Communications, 2019 Human antibodies cross-reactive for several viruses within the Ebolavirus genus have been identified. Here the authors present the crystal structure of such a neutralizing monoclonal antibody (mAb) targeting the stalk of Bundibugyo virus glycoprotein and
Liam B. King +11 more
doaj +1 more source