Results 31 to 40 of about 212 (104)

In Silico Identification of Antiviral Peptides as Potential Leads Against Sudan Ebolavirus VP‐40

BioMed Research International, Volume 2026, Issue 1, 2026.
The continued reemergence of Ebola virus epidemics remains a global health concern, largely due to limited therapeutic interventions. This study is aimed at identifying and characterizing antiviral peptides as potential lead candidates against the Sudan Ebola virus.
Boniface Omara, Kenedy Kiyimba, Fatoumata G. Fofana, Oudou Diabaté, Walter Odur, Daudi Jjingo, Jacob Stanley Iramiot, Peace Draleru, Joan Achia, Muhammad Shafiq, Zaheer Ul-Haq, Hedmon Okella, Steven Odongo, Swaran J. S. Flora   +13 more
wiley   +1 more source

Newly discovered ebola virus associated with hemorrhagic fever outbreak in Uganda.

PLoS Pathogens, 2008
Over the past 30 years, Zaire and Sudan ebolaviruses have been responsible for large hemorrhagic fever (HF) outbreaks with case fatalities ranging from 53% to 90%, while a third species, Côte d'Ivoire ebolavirus, caused a single non-fatal HF case.
Jonathan S Towner, Tara K Sealy, Marina L Khristova, César G Albariño, Sean Conlan, Serena A Reeder, Phenix-Lan Quan, W Ian Lipkin, Robert Downing, Jordan W Tappero, Samuel Okware, Julius Lutwama, Barnabas Bakamutumaho, John Kayiwa, James A Comer, Pierre E Rollin, Thomas G Ksiazek, Stuart T Nichol   +17 more
doaj   +1 more source

High‐Resolution Mapping of Environmental Suitability for Reported Ebola Spillover Events in Uganda to Inform Surveillance and Preparedness

Journal of Tropical Medicine, Volume 2026, Issue 1, 2026.
Background Uganda experiences recurrent Ebola disease (EBOD) outbreaks, yet national suitability maps often pool virus species or are too coarse for district‐level planning. We aimed to generate species‐resolved, 1 km relative environmental suitability surfaces for reported Ebola spillover events in Uganda; quantify the contribution of environmental ...
George Paasi, Nancy Malaika, Sam Okware, Peter Olupot-Olupot, Priya Gusain   +4 more
wiley   +1 more source

Systematic Review and Meta‐Analysis of Emerging Viral Zoonotic Diseases, 2016–2026

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Emerging viral zoonoses—infections caused by viruses that cross the species barrier from animal reservoirs into human populations—account for the majority of emerging infectious disease (EID) events and now constitute a defining threat to global health security.
Pan Tao, Ying-an Zang, Jing Wang, Feng Cong, Ming Liao, Jianchao Wei   +5 more
wiley   +1 more source

From reactive trials to regional vaccine sovereignty: a pan-ebolavirus vaccine-readiness framework for East Africa’s Sudan virus and Bundibugyo virus threats

Frontiers in Public Health
Vaccines have transformed preparedness for Zaire ebolavirus disease, but East Africa still faces recurrent risk from Sudan virus and Bundibugyo virus, for which licensed and routinely deployable vaccines remain unavailable.
Okechukwu Paul-Chima Ugwu, Chinyere Nneoma Ugwu, Godson Emeka Anyanwu, Mariam Basajja, Maryann Chiamaka Ebuoh   +4 more
doaj   +1 more source

Bundibugyo ebolavirus Survival Is Associated with Early Activation of Adaptive Immunity and Reduced Myeloid-Derived Suppressor Cell Signaling

mBio, 2021
Ebolaviruses Bundibugyo virus (BDBV) and Ebola virus (EBOV) cause fatal hemorrhagic disease in humans and nonhuman primates. While the host response to EBOV is well characterized, less is known about BDBV infection.
Courtney Woolsey, Viktoriya Borisevich, Krystle N. Agans, Karla A. Fenton, Robert W. Cross, Thomas W. Geisbert   +5 more
doaj   +1 more source

Drug Repurposing Investigation for Combating Ebola Virus Disease: Database Mining, Docking Calculations, Molecular Dynamics, and Density Functional Theory Study

ChemistryOpen, Volume 14, Issue 12, December 2025.
DrugBank database is mined to hunt prospective Ebola virus (EBOV) VP35 inhibitors utilizing docking calculations, molecular dynamics, molecular mechanics/generalized Born surface area binding energy calculations, and density functional theory computations.
Alaa H. M. Abdelrahman, Gamal A. H. Mekhemer, Peter A. Sidhom, Mohamed A. El‐Tayeb, Shahzeb Khan, Mahmoud A. A. Ibrahim   +5 more
wiley   +1 more source

Non-Ebola Filoviruses: Potential Threats to Global Health Security

Viruses
Filoviruses are negative-sense single-stranded RNA viruses often associated with severe and highly lethal hemorrhagic fever in humans and nonhuman primates, with case fatality rates as high as 90%.
Yannick Munyeku-Bazitama, Francois Edidi-Atani, Ayato Takada   +2 more
doaj   +1 more source

Ebola: The bundibugyo virus is back

South Sudan Medical Journal
No abstract.
openaire   +2 more sources

Preparing for Ebola: Strengthening Nursing Readiness in the United States

Nursing Open, Volume 13, Issue 9, September 2026.
Benjamin Lindsay
wiley   +1 more source