Passaging of a Newcastle disease virus pigeon variant in chickens results in selection of viruses with mutations in the polymerase complex enhancing virus replication and virulence [PDF]
Some Newcastle disease virus (NDV) variants isolated from pigeons (pigeon paramyxovirus type 1; PPMV-1) do not show their full virulence potential for domestic chickens but may become virulent upon spread in these animals.
Peeters, B.P.H. +9 more
core +2 more sources
DrugBank database is mined to hunt prospective Ebola virus (EBOV) VP35 inhibitors utilizing docking calculations, molecular dynamics, molecular mechanics/generalized Born surface area binding energy calculations, and density functional theory computations.
Alaa H. M. Abdelrahman +5 more
wiley +1 more source
Cloned defective interfering influenza virus protects ferrets from pandemic 2009 influenza A virus and allows protective immunity to be established [PDF]
Influenza A viruses are a major cause of morbidity and mortality in the human population, causing epidemics in the winter, and occasional worldwide pandemics.
Cheung, Linda +39 more
core +2 more sources
Following the Bundibugyo virus disease outbreak reported in the Democratic Republic of the Congo in May 2026, we reviewed all known Ebola disease cases outside Africa and found that intercontinental transmission risk remains low.
Nicholas G Davies
doaj +1 more source
Resurgence of Ebola in Uganda: Response Strategies, Lessons Learned, and Future Directions
ABSTRACT Introduction The recent resurgence of Ebola virus disease (EVD), specifically the Sudan virus strain, in Uganda highlights the ongoing threat of emerging infectious diseases. This article aims to analyze the multifaceted factors contributing to this resurgence, evaluate the public health impact, and assess the effectiveness of response ...
Majani Edward +3 more
wiley +1 more source
Can the Ebola Zaire vaccine stop the Bundibugyo virus?
Reports indicate that the WHO and Africa CDC approved the DRC government’s request to release Ervebo vaccines for use against the Bundibugyo virus in August.
Edward Kenyi
doaj +1 more source
Marburg Virus Disease: A Narrative Review
ABSTRACT Background and Aims Given the recent deadly outbreaks of the Marburg virus (MARV), in early 2023 in Tanzania and Equatorial Guinea, and the most recent one in Rwanda in 2024, there has been renewed attention across Africa on the threat posed by the re‐emergence of MARV as a growing concern for public health.
Arash Letafati +4 more
wiley +1 more source
Exchange of the C-terminal part of VP3 from very virulent infectious bursal disease virus results in an attenuated virus with a unique antigenic structure [PDF]
Infectious bursal disease virus (IBDV) is the major viral pathogen in the poultry industry. Live attenuated serotype 1 vaccine strains are commonly used to protect susceptible chickens during their first 6 weeks of life. Wild-type serotype 1 IBDV strains
Peeters, B.P.H. +6 more
core +1 more source
Non-Ebola Filoviruses: Potential Threats to Global Health Security
Filoviruses are negative-sense single-stranded RNA viruses often associated with severe and highly lethal hemorrhagic fever in humans and nonhuman primates, with case fatality rates as high as 90%.
Yannick Munyeku-Bazitama +2 more
doaj +1 more source
ABSTRACT Background and Aims The Dinga Dinga Virus (DDV) has emerged as a mysterious disease gripping women in Uganda, raising alarm due to its unusual and distressing “dancing” like symptoms. These symptoms, characterized by involuntary movements resembling dance, suggest possible neurological involvement, though the exact pathogen remains ...
Sabrina Sharmin +3 more
wiley +1 more source

