Mutations in the Schmallenberg virus Gc glycoprotein facilitate cellular protein synthesis shutoff and restore pathogenicity of NSs deletion mutants in mice [PDF]
, 2016 Serial passage of viruses in cell culture has been traditionally used to attenuate virulence and identify determinants of viral pathogenesis. In a previous study, we found that a strain of Schmallenberg virus (SBV) serially passaged in tissue culture ...
Aislynn Taggart +13 more
core +1 more source
Emerging Infectious Diseases, 2017 Toscana and sandfly fever Sicilian viruses (TOSV and SFSV, respectively), both transmitted by sand flies, are prominent human pathogens in the Old World.
Nazli Ayhan +4 more
doaj +1 more source
Knockdown of piRNA pathway proteins results in enhanced Semliki forest virus production in mosquito cells [PDF]
, 2013 The exogenous siRNA pathway is important in restricting arbovirus infection in mosquitoes. Less is known about the role of the PIWI-interacting RNA pathway, or piRNA pathway, in antiviral responses. Viral piRNA-like molecules have recently been described
Donald, Claire L. +8 more
core +3 more sources
Prophylactic and therapeutic intervention of Punta Toro virus (Phlebovirus, Bunyaviridae) infection in hamsters with interferon alfacon-1 [PDF]
Antiviral Research, 2008 Punta Toro virus (PTV) is a member of the Bunyaviridae family, genus Phlebovirus, related to the highly pathogenic Rift Valley fever virus (RVFV). It produces a disease in hamsters that models severe Rift Valley fever (RVF) in humans. The recent outbreak of RVF in Kenya stresses the need to identify prophylactic and therapeutic measures for preventing ...
Gowen, Brian B. +4 more
openaire +3 more sources
Genetic Characterization of Archived Bunyaviruses and their Potential for Emergence in Australia
Emerging Infectious Diseases, 2016 To better understand the diversity of bunyaviruses and their circulation in Australia, we sequenced 5 viruses (Gan Gan, Trubanaman, Kowanyama, Yacaaba, and Taggert) isolated and serologically identified 4 decades ago as members of the family Bunyaviridae.
Bixing Huang +11 more
doaj +1 more source
An Outbreak of Crimean-Congo hemorrhagic fever (CCHF) in South Africa in 2022
Global Biosecurity, 2023 Crimean-Congo Hemorrhagic Fever (CCHF) is a vector-borne disease caused by a tick-borne virus (Nairovirus) of the Bunyaviridae family. The onset of CCHF is sudden, with initial signs and symptoms including headache, high fever, back pain, joint pain ...
Utkarsh Betodkar +2 more
doaj +1 more source
Non-structural proteins of arthropod-borne bunyaviruses: roles and functions [PDF]
, 2013 Viruses within the Bunyaviridae family are tri-segmented, negative-stranded RNA viruses. The family includes several emerging and re-emerging viruses of humans, animals and plants, such as Rift Valley fever virus, Crimean-Congo hemorrhagic fever virus ...
Alain Kohl +17 more
core +3 more sources
Pneumonitis in Syrian golden hamsters (Mesocricetus auratus) infected with Rio Mamoré virus (family Bunyaviridae, genus Hantavirus) [PDF]
Virus Research, 2014 Rio Mamoré virus is an etiological agent of hantavirus pulmonary syndrome in South America. The purpose of this study was to determine whether Rio Mamoré virus strain HTN-007 in Syrian golden hamsters is pathogenic. None of 37 adult hamsters infected by intramuscular injection of HTN-007, including 10 animals killed on Day 42 or 43 post-inoculation ...
Mary Louise, Milazzo +2 more
openaire +2 more sources
The First Reported Case of California Encephalitis in More Than 50 Years
Emerging Infectious Diseases, 2001 A recent case of California encephalitis, a rare mosquito-borne viral disease, represents only the fourth ever reported and the first since the initial three cases in 1945.
Bruce F. Eldridge +3 more
doaj +1 more source
Metagenomic-based Surveillance of Pacific Coast tick Dermacentor occidentalis Identifies Two Novel Bunyaviruses and an Emerging Human Ricksettsial Pathogen. [PDF]
, 2017 An increasing number of emerging tick-borne diseases has been reported in the United States since the 1970s. Using metagenomic next generation sequencing, we detected nucleic acid sequences from 2 novel viruses in the family Bunyaviridae and an emerging ...
Bouquet, Jerome +5 more
core +2 more sources