Tamdy virus pathogenesis in immunocompetent and immunocompromised mouse models
VirulenceTamdy virus (TAMV) is one of the zoonotic tick-borne bunyaviruses that have emerged as global public health threats in recent decades. To date, however, TAMV pathogenesis remains poorly understood.
Mingxue Cui +8 more
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Functional analysis of the orthobunyavirus nucleocapsid (N) protein [PDF]
, 2008 Bunyamwera virus (BUNV) is the prototype of the family Bunyaviridae. It has a tripartite genome consisting of negative sense RNA segments called large (L), medium (M) and small (S). The S segment encodes the nucleocapsid protein (N) of 233 amino acids.
Eifan, Saleh A.
core
Rapid identification of Australian bunyavirus isolates belonging to the Simbu serogroup using indirect ELISA formats. [PDF]
, 1997 The Bunyavirus genus, belonging to the Bunyaviridae family, is comprised of a large group of antigenically and geographically disparate arthropod-borne viruses of medical and veterinary significance. In Australia, viruses belonging to the Simbu serogroup
Ross A. Lunt +6 more
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Bunyamwera bunyavirus nonstructural protein NSs is a nonessential gene product that contributes to viral pathogenesis [PDF]
, 2001 Bunyamwera virus (family Bunyaviridae, genus Bunyavirus) contains a tripartite negative-sense RNA genome. The smallest RNA segment, S, encodes the nucleocapsid protein N and a nonstructural protein, NSs, in overlapping reading frames. We have generated a
Bridgen, A +11 more
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A novel strain of Leishmania braziliensis harbors not a toti- but a bunyavirus. [PDF]
Leishmania is a genus of the family Trypanosomatidae that unites obligatory parasitic flagellates causing a variety of vector-borne diseases collectively called leishmaniasis. The symptoms range from relatively innocuous skin lesions to complete failures
Petr Volf +25 more
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The Potential for Reassortment between Oropouche and Schmallenberg Orthobunyaviruses
Viruses, 2017 A number of viruses within the Peribunyaviridae family are naturally occurring reassortants, a common phenomenon for segmented viruses. Using a minigenome-reporter and virus-like particle (VLP) production assay, we have accessed the potential of ...
Natasha L. Tilston-Lunel +3 more
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Rift Valley Fever Phlebovirus Reassortment Study in Sheep
VirusesRift Valley fever (RVF) in ungulates and humans is caused by a mosquito-borne RVF phlebovirus (RVFV). Live attenuated vaccines are used in livestock (sheep and cattle) to control RVF in endemic regions during outbreaks.
Velmurugan Balaraman +14 more
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Bunyavirus requirement for endosomal K+ reveals new roles of cellular ion channels during infection [PDF]
, 2018 In order to multiply and cause disease a virus must transport its genome from outside the cell into the cytosol, most commonly achieved through the endocytic network.
John N Barr +26 more
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VirulenceOropouche virus (OROV), an arbovirus belonging to the Orthobunyavirus genus and Peribunyaviridae family, is the causative agent of the so-called “sloth fever.” The virus primarily relies on the midge vector Culicoides paraensis for transmission ...
Michaela Cain, Hinh Ly
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Prevalence of SFTSV among Asian House Shrews and Rodents, China, January–August 2013
Emerging Infectious Diseases, 2014 To evaluate the role of small mammals as hosts of severe fever with thrombocytopenia syndrome virus (SFTSV), we tested serum samples from rodents and shrews in China, collected in 2013.
Jian-Wei Liu +12 more
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