Results 81 to 90 of about 6,619 (255)

The Native Orthobunyavirus Ribonucleoprotein Possesses a Helical Architecture

mBio, 2022
The Bunyavirales order is the largest group of negative-sense RNA viruses, containing many lethal human pathogens for which approved anti-infective measures are not available.
Francis R. Hopkins, Beatriz Álvarez-Rodríguez, George R. Heath, Kyriakoulla Panayi, Samantha Hover, Thomas A. Edwards, John N. Barr, Juan Fontana   +7 more
doaj   +1 more source

Strategic Preparedness of Broad‐Spectrum Antivirals for Rapid Response Towards Next Pandemics

Small Science, Volume 6, Issue 1, January 2026.
Nanoengineered broad‐spectrum antivirals (BSAs) represent a transformative approach to pandemic preparedness. Unlike virus‐specific drugs requiring separate development, BSAs act across multiple viral families through nanoengineering strategies that enhance solubility, bioavailability, and host‐targeted activity.
Sanoj Rejinold N, Geun‐woo Jin, Jin‐Ho Choy   +2 more
wiley   +1 more source

Advances in Microbial Diagnostics: Machine Learning and Nanotechnology for Zoonotic Disease Control

WIREs Nanomedicine and Nanobiotechnology, Volume 18, Issue 1, January/February 2026.
This review highlights how integrating machine learning with nanotechnology enables enhanced diagnostics, personalized treatments, and the prediction of outbreaks for zoonotic diseases, offering a unified framework to advance global health. ABSTRACT Zoonotic diseases pose significant global health threats, with microbial pathogens, including bacteria ...
Narges Lotfalizadeh, Cinzia Santucciu, Valentina Chisu, Helia Sepahvand, Abbas Rahdar, Razieh Behzadmehr, Octavio Luiz Franco, Guettari Moez, Luiz Fernando Romanholo Ferreira   +8 more
wiley   +1 more source

In Vitro Evaluation of Bunyavirus T Cell Immunity. [PDF]

Methods Mol Biol
Characterization and quantitation of T cell responses following infection and/or vaccination can provide insight into mechanisms of host cell immunity that provide resolution of acute infection or protection from future infection or disease. While these types of studies are very advanced for viruses such as HIV, influenza, and SARS-CoV-2, they are less
McElroy AK.
europepmc   +3 more sources

Viral discovery and diversity in trypanosomatid protozoa with a focus on relatives of the human parasite Leishmania. [PDF]

, 2017
Knowledge of viral diversity is expanding greatly, but many lineages remain underexplored. We surveyed RNA viruses in 52 cultured monoxenous relatives of the human parasite <i>Leishmania</i> ( <i>Crithidia</i> and <i> ...
Akopyants, N.S., Beverley, S.M., Butenko, A., d'Avila-Levy, C.M., Dobson, D.E., Fasel, N., Frolov, A.O., Grybchuk, D., Konovalovas, A., Kostygov, A.Y., Kulich, P., Lukeš, J., Lye, L.F., Moravcová, J., Plevka, P., Rogozin, I.B., Serva, S., Votýpka, J., Yurchenko, V., Zangger, H.   +19 more
core   +1 more source

Unveiling Novel Viral Diversity, Biogeography, and Host Networks in Wildlife Through High‐Throughput Sequencing Data Mining

Advanced Science, Volume 12, Issue 46, December 11, 2025.
Analysis of 57 536 high‐throughput sequencing datasets uncovers a vast, hidden world of viruses in wildlife. The researchers reveal significant geographic and host‐specific patterns of viruses, and their surprising cross‐species transmissions, such as avian flu viruses infecting goats.
Hai Wang, Yafei Meng, Xiaoyuan Chen, Xinyuan Cui, Qian Zuo, Na Han, Xianghui Liang, Xuejuan Shen, Caiwu Li, Desheng Li, Fumin Wang, Liangping He, Rujian Chen, Xingbang Lu, Wenjie You, Aiping Wu, Rui‐Ai Chen, Wu Chen, Chan Ding, Yongyi Shen   +19 more
wiley   +1 more source

Virus-induced translational arrest through 4EBP1/2-dependent decay of 5'-TOP mRNAs restricts viral infection [PDF]

, 2015
The mosquito-transmitted bunyavirus, Rift Valley fever virus (RVFV), is a highly successful pathogen for which there are no vaccines or therapeutics. Translational arrest is a common antiviral strategy used by hosts.
Cherry, S., Hackett, B. A., Herrmann, C., Hopkins, K. C., Menghani, S. V., Panda, D., Sabin, L. R., Tartell, M. A., Taschuk, F.   +8 more
core   +1 more source

Implementing a Multidimensional Nursing Protocol in Dabie Bandavirus‐Induced SFTS With Critical Complications

Clinical Case Reports, Volume 13, Issue 12, December 2025.
ABSTRACT This case demonstrates that a comprehensive, multidimensional nursing protocol—encompassing intensive monitoring, complication‐specific management, and rigorous infection control—is associated with favorable outcomes in this critically ill severe fever with thrombocytopenia syndrome (SFTS) patient with complex comorbidities like Parkinson's ...
Yongping Qiu, Minrui Li, Tingting Li, Jing Liu, Xiaodan Zhu, Shaoqin Zheng, Sha Yang   +6 more
wiley   +1 more source

Isolation of Oropouche Virus from Febrile Patient, Ecuador

Emerging Infectious Diseases, 2018
We report identification of an Oropouche virus strain in a febrile patient from Ecuador by using metagenomic sequencing and real-time reverse transcription PCR. Virus was isolated from patient serum by using Vero cells. Phylogenetic analysis of the whole-
Emma L. Wise, Steven T. Pullan, Sully Márquez, Verónica Paz, Juan D. Mosquera, Sonia Zapata, Simon K. Jackson, Gyorgy Fejer, Gabriel Trueba, Christopher H. Logue   +9 more
doaj   +1 more source

Clinical and Laboratory Predictors of Poor Neurological Outcomes Following Infectious Encephalitis: Systematic Review and Meta‐Analysis

European Journal of Neurology, Volume 32, Issue 12, December 2025.
Clinical and laboratory predictors of long‐term neurological outcomes after infectious encephalitis. ABSTRACT Background and Objectives Infectious encephalitis is a serious global health problem linked to high rates of mortality and morbidity. However, clinical and laboratory factors that impact neurological outcomes following infectious encephalitis ...
Thomas Johnson, Mia Venables, Babak Soleimani, Laurissa Havins, Annapoorna Kannan, Gregory Holt, Jonathan Cleaver, Adam E. Handel, Ava Easton, Defne Saatci, Lahiru Handunnetthi   +10 more
wiley   +1 more source