Interscalene nerve block with plain bupivacaine versus liposomal bupivacaine for arthroscopic rotator cuff repair: A randomized controlled trial [PDF]
Saudi Journal of AnaesthesiaBackground: Although single injections with anesthetics are commonly administered given their safety, their short-acting nature limits pain control.
Paul Sang Lee +8 more
doaj +2 more sources
Real-World Pharmacovigilance Analysis of Adverse Events Associated with Liposomal Bupivacaine and Bupivacaine [PDF]
Journal of Pain ResearchDong Xu Chen,1,2,* Xuan Ming Chen,3,* Shou Ming Chen,1,2 Yi Da Wang3 1Department of Anesthesiology, West China Second Hospital, Sichuan University, Chengdu, People’s Republic of China; 2Key Laboratory of Birth Defects and Related Diseases of ...
Chen DX, Chen XM, Chen SM, Wang YD
doaj +2 more sources
COMPARISON OF BUPIVACAINE AND BUPIVACAINE WITH FENTANYL IN CONTINUOUS EXTRADURAL ANALGESIA DURING LABOUR [PDF]
British Journal of Anaesthesia, 1989 In a randomized, double-blind study of 39 mothers in labour, we have compared a loading dose of 0.5% bupivacaine 6.0 ml and fentanyl 100 micrograms given extradurally, followed by an infusion of 0.08% bupivacaine 15 ml h-1 plus fentanyl 37.5 micrograms h-1, with a loading dose of 0.5% bupivacaine 6.0 ml and saline 2.0 ml, followed by an extradural ...
R. A. Elton +3 more
openaire +6 more sources
Differences in sensory nerve block between levobupivacaine and bupivacaine at low concentrations in humans and animals. [PDF]
PLoS ONEPhysiochemical properties of levobupivacaine and bupivacaine are identical, but pharmacokinetic and pharmacodynamics properties differ due to stereoselective interactions at the molecular sites of action.
Akiyuki Sakamoto +3 more
doaj +2 more sources
Comparison of pain with bupivacaine and bupivacaine-sufentanil combination in women undergoing cesarean section with spinal anesthesia: A double-blind randomized clinical trial [PDF]
Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān, 2022 Introduction: Today, spinal anesthesia is the method of choice for most cesarean sections. Postoperative pain control has always been one of the main concerns of anesthesiologists.
Hasan Zabetian +3 more
doaj +1 more source
Bioengineered, 2022 The study aimed to explore the effects of local anesthetic bupivacaine on bladder cancer cells in vivo and in vitro. The cytotoxicity was detected by MTT assay. Apoptosis was measured by Hoechst 33342 staining and TUNEL.
Jianli Hao, Weiqing Zhang, Zeqing Huang
semanticscholar +1 more source
Frontiers in Oncology, 2021 Non-small cell lung cancer (NSCLC) is a prevalent malignancy with high mortality and poor prognosis. Bupivacaine serves as a widely used local anesthetic and presents potential anti-tumor activity.
Jian-Hua Gu +6 more
doaj +1 more source
Comparison of addition of fentanyl or clonidine to Intrathecal bupivacaine versus Intrathecal bupivacaine alone for lower limb surgeries in elderly patients: A prospective, randomised study: Intrathecal fentanyl/clonidine ± bupivacaine for surgery in elderly [PDF]
Serbian Journal of Anesthesia and Intensive Therapy, 2023 Orthopaedic long bone fracture surgeries in elderly patients have their own inherent risks during anaesthesia. We aimed to compare the effect of adding clonidine or fentanyl to low dose intrathecal bupivacaine as opposed to intrathecal bupivacaine alone.
Bhat Pai Rohini V. +5 more
doaj +1 more source
BMC Pharmacology and Toxicology, 2021 Background Bupivacaine blocks many ion channels in the heart muscle, causing severe cardiotoxicity. Small-conductance calcium-activated potassium type 2 channels (SK2 channels) are widely distributed in the heart cells and are involved in relevant ...
Hongfei Chen +3 more
doaj +1 more source