COMPARISON OF BUPIVACAINE AND BUPIVACAINE WITH FENTANYL IN CONTINUOUS EXTRADURAL ANALGESIA DURING LABOUR [PDF]
British Journal of Anaesthesia, 1989 In a randomized, double-blind study of 39 mothers in labour, we have compared a loading dose of 0.5% bupivacaine 6.0 ml and fentanyl 100 micrograms given extradurally, followed by an infusion of 0.08% bupivacaine 15 ml h-1 plus fentanyl 37.5 micrograms h-1, with a loading dose of 0.5% bupivacaine 6.0 ml and saline 2.0 ml, followed by an extradural ...
Gregory C. Jones +3 more
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Real-World Pharmacovigilance Analysis of Adverse Events Associated with Liposomal Bupivacaine and Bupivacaine [PDF]
Journal of Pain ResearchDong Xu Chen,1,2,* Xuan Ming Chen,3,* Shou Ming Chen,1,2 Yi Da Wang3 1Department of Anesthesiology, West China Second Hospital, Sichuan University, Chengdu, People’s Republic of China; 2Key Laboratory of Birth Defects and Related Diseases of ...
Chen DX, Chen XM, Chen SM, Wang YD
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Comparison of pain with bupivacaine and bupivacaine-sufentanil combination in women undergoing cesarean section with spinal anesthesia: A double-blind randomized clinical trial [PDF]
Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān, 2022 Introduction: Today, spinal anesthesia is the method of choice for most cesarean sections. Postoperative pain control has always been one of the main concerns of anesthesiologists.
Hasan Zabetian +3 more
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Frontiers in Oncology, 2021 Non-small cell lung cancer (NSCLC) is a prevalent malignancy with high mortality and poor prognosis. Bupivacaine serves as a widely used local anesthetic and presents potential anti-tumor activity.
Jian-Hua Gu +6 more
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Comparison of addition of fentanyl or clonidine to Intrathecal bupivacaine versus Intrathecal bupivacaine alone for lower limb surgeries in elderly patients: A prospective, randomised study: Intrathecal fentanyl/clonidine ± bupivacaine for surgery in elderly [PDF]
Serbian Journal of Anesthesia and Intensive Therapy, 2023 Orthopaedic long bone fracture surgeries in elderly patients have their own inherent risks during anaesthesia. We aimed to compare the effect of adding clonidine or fentanyl to low dose intrathecal bupivacaine as opposed to intrathecal bupivacaine alone.
Bhat Pai Rohini V. +5 more
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BMC Pharmacology and Toxicology, 2021 Background Bupivacaine blocks many ion channels in the heart muscle, causing severe cardiotoxicity. Small-conductance calcium-activated potassium type 2 channels (SK2 channels) are widely distributed in the heart cells and are involved in relevant ...
Hongfei Chen +3 more
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The effect of adjuvant midazolam compared with fentanyl on the duration of spinal anesthesia with 0.5% bupivacaine in opium abusers [PDF]
Korean Journal of Anesthesiology, 2012 BackgroundThere are a number of adjuvants to be used for local anesthetics in spinal block. The aim of this study was to demonstrate the possible effect of intrathecal midazolam compared with bupivacaine as adjuvants in spinal anesthesia with bupivacaine
Farhad Safari +2 more
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Bupivacaine Liposomal versus Bupivacaine: Comparative Review [PDF]
Hospital Pharmacy, 2014 Bupivacaine liposomal injection was recently approved by the US Food and Drug Administration (FDA) as a local anesthetic for use in management of postsurgical pain in adults. When compared to placebo, bupivacaine liposomal decreases postoperative pain and opioid use.
Noviasky, John +4 more
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Advances in Pharmacological and Pharmaceutical Sciences, 2020 Objective. The purpose of this study is to determine whether (1) liposomal bupivacaine is chondrotoxic; (2) the chondrotoxicity of liposomal bupivacaine differs from standard bupivacaine; and (3) chondrotoxic effects are time dependent.
Travis Farmer +5 more
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