Results 1 to 10 of about 42,379 (196)
COMPARISON OF BUPIVACAINE AND BUPIVACAINE WITH FENTANYL IN CONTINUOUS EXTRADURAL ANALGESIA DURING LABOUR [PDF]
In a randomized, double-blind study of 39 mothers in labour, we have compared a loading dose of 0.5% bupivacaine 6.0 ml and fentanyl 100 micrograms given extradurally, followed by an infusion of 0.08% bupivacaine 15 ml h-1 plus fentanyl 37.5 micrograms h-1, with a loading dose of 0.5% bupivacaine 6.0 ml and saline 2.0 ml, followed by an extradural ...
Gregory C. Jones+3 more
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Bupivacaine Liposomal versus Bupivacaine: Comparative Review [PDF]
Bupivacaine liposomal injection was recently approved by the US Food and Drug Administration (FDA) as a local anesthetic for use in management of postsurgical pain in adults. When compared to placebo, bupivacaine liposomal decreases postoperative pain and opioid use.
Noviasky, John+4 more
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Liposomal bupivacaine: a review of a new bupivacaine formulation
Many attempts have been made to increase the duration of local anesthetic action. One avenue of investigation has focused on encapsulating local anesthetics within carrier molecules to increase their residence time at the site of action. This article aims to review the literature surrounding the recently approved formulation of bupivacaine, which ...
Praveen Chahar, Kenneth C. Cummings
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Extradural S(-)-bupivacaine: comparison with racemic RS-bupivacaine
Bupivacaine has a chiral centre and is currently available as a racemic mixture of its two enantiomers: R(+)-bupivacaine and S(-)-bupivacaine. Preclinical studies have demonstrated that there is enantiomer selectivity of action with the bulk of central nervous system and cardiovascular toxicity residing with the R(+) isomer.
C. R. Cox+5 more
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The use of bupivacaine in labour [PDF]
THE USE OF CONTINUOUS LUI~IBAlq EPIDURAL BLOCK for pain relief during the 1st and 2nd stages of labour was first described by Flowers, Hellman and Hingson in 1949.1 Today, some twenty years later, this technique is commonly used in Canada in the majority of the larger hospitals dealing with obstetrical cases.
D. V. Catton, R. A. Browne
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COMPARISON OF CARBONATED BUPIVACAINE AND BUPIVACAINE HYDROCHLORIDE FOR EXTRADURAL ANAESTHESIA
A double-blind comparison of carbonated bupivacaine and bupivacaine hydrochloride in extradural anaesthesia was performed in 40 patients. No significant differences in the onset times, sensory blockade, motor blockade and duration of anaesthesia were demonstrated. Carbonated bupivacaine does not appear to offer any advantage over the hydrochloride salt
B.G. Covino+3 more
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Response to “Bupivacaine Liposomal versus Bupivacaine: Comparative Review” [PDF]
To the Editor: The recent article, “Bupivacaine Liposomal Versus Bupivacaine: Comparative Review,” by Noviasky et al [Hosp Pharm. 2014;49(6):539-543] is a valiant effort to review this topic. However, the authors have made a critical oversight in their attempt to interpret analgesic efficacy based solely on pain intensity.
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Sixty children undergoing inguinal or urogenital surgery were allocated randomly to three groups to receive a caudal injection of either 0.125% bupivacaine 0.75 mL kg-1 with 0.5% midazolam 50 micrograms kg-1 (n = 20) or with 1% morphine chlorhydrate 0.05 mg kg-1 (n = 20), or bupivacaine alone (n = 20) after surgery under general anaesthesia. There were
B. Büyükkidan+4 more
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Comparison of Caudal Epidural Bupivacaine with Bupivacaine plus Tramadol and Bupivacaine plus Ketamine for Postoperative Analgesia in Children [PDF]
This study compared the effect of single-dose caudal epidural bupivacaine, bupivacaine plus ketamine and bupivacaine plus tramadol for postoperative pain management in children having surgery for inguinal hernia. Following ethics committee approval and informed parental consent, 75 children ASA PS I and II, between three and nine years of age and ...
Choudhuri Ah+3 more
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