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Predicting the Density of Bupivacaine and Bupivacaine-Opioid Combinations

Anesthesia & Analgesia, 2002
Manipulating the density of local anesthetic solutions by using a simple formula may be clinically useful in producing optimal density solutions for spinal anesthesia under a variety of clinical conditions.
Gary M. Stocks   +2 more
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Bupivacaine Versus Liposomal Bupivacaine For Pain Control

Drug Research, 2017
AbstractLocal infiltrations and regional blocks have been some of the effective ways employed to manage and control post-operative pain. One of the limitations of administration of local anesthesia drugs in post-operative conditions is its inability to act for a longer period of time.
Siavash Beiranvand   +1 more
openaire   +3 more sources

The clinical effectiveness of epidural bupivacaine, bupivacaine with lidocaine, and bupivacaine with fentanyl for labor analgesia

Journal of Clinical Anesthesia, 1991
To examine the efficacy of bupivacaine alone and in combination with lidocaine or fentanyl for epidural analgesia during labor.Randomized, single-blind study.Labor and delivery unit at a university medical center.Forty-five primiparas requesting epidural analgesia.Following epidural placement at L3-4 interspace, patients received either bupivacaine 0.5%
Robert Goldstein   +2 more
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A COMPARISON OF BUPIVACAINE AND ALKALINIZED BUPIVACAINE IN BRACHIAL PLEXUS ANESTHESIA

Anesthesia & Analgesia, 1987
To define the effect of alkalinization of bupivacaine 0.5% in subclavian perivascular brachial plexus blockade, the time to onset, time to peak effect, and 6-hour regression of sensory and motor blockade were determined. Sixty physical status ASA I and II patients were randomly allocated to one of two groups and a double-blind design was used: group I (
M. D. Bedder, D. B. Craig, R. Kozody
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New formulations of bupivacaine for the treatment of postoperative pain: liposomal bupivacaine and SABER-Bupivacaine

Expert Opinion on Pharmacotherapy, 2014
Although generally considered both safe and effective, local anesthetics are often used in conjunction with opioids postoperatively in part because of the limited duration of drug action of local anesthetics. Much interest exists in extending the duration of local anesthetics' effects, which may reduce the requirement for opioid pain medications that ...
Aaron Skolnik, Tong J. Gan
openaire   +3 more sources

Comparison of fentanyl–bupivacaine or midazolam–bupivacaine mixtures with plain bupivacaine for caudal anaesthesia in children

Pediatric Anesthesia, 2003
Summary Background: The aim of this study was to evaluate the intensity and effectiveness of 0.75 ml·kg−1 bupivacaine 0.25% with the addition of fentanyl or midazolam for caudal block in children undergoing inguinal herniorrhaphy. Methods: Seventy‐five children were allocated randomly to three groups to receive a caudal block with either 0.25 ...
Baris, S   +5 more
openaire   +3 more sources

Comparative Evaluation of Intrathecal Bupivacaine Alone, Bupivacaine-fentanyl, and Bupivacaine-dexmedetomidine in Caesarean Section

Drug Research, 2014
In this study, we aimed to compare the effects of bupivacaine alone, bupivacaine plus fentanyl, and bupivacaine plus dexmedetomidine for postoperative analgesia in women undergoing cesarean section under spinal anesthesia.90 term parturients scheduled to have elective cesarean section and ASA physical status I or II were allocated randomly into 3 ...
Y. Xu, Guiyu Wang, Yinghua Sun
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