Results 91 to 100 of about 104,116 (405)
BU10038 as a safe opioid analgesic with fewer side-effects after systemic and intrathecal administration in primates [PDF]
, 2019 © 2019 British Journal of Anaesthesia. Published by Elsevier Ltd. All rights reserved.Background: The marked increase in mis-use of prescription opioids has greatly affected our society. One potential solution is to develop improved analgesics which have
Cami-Kobeci, Gerta +9 more
core +4 more sources
Advanced Healthcare Materials, EarlyView.Metal‐organic frameworks (MOFs) have been synthesized using calcium (Ca‐MOF), magnesium (Mg‐MOF), and as hybrids (Ca/Mg‐MOF) for bone healing applications. MOFs are integrated into hydrogel polymer networks for injectable, sprayable, and coating applications.
Cho‐E Choi +4 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Injectable POEGMA‐DA hydrogels, dual‐crosslinked via dopamine self‐polymerization and dynamic hydrazone bonds, provide a safer alternative to invasive wound closure methods and toxic bioadhesives. Mimicking skin‐like mechanics, they achieve effective tissue adhesion for acute dermal wounds, supporting improved healing outcomes, including reducing ...
Gurpreet Kaur Randhawa +6 more
wiley +1 more source
An Exploratory Study of Suboxone (Buprenorphine/ Naloxone) Film Splitting: Cutting Methods, Content Uniformity, and Stability [PDF]
, 2019 Suboxone films are U.S. Food and Drug Administration approved to treat opioid dependence. While the package insert states that films should not be cut, physicians often prescribe film fractions for treatment and tapering. There is no data to support this
Conn, Kelly +6 more
core +1 more source
Growth Hormone‐Loaded 3D Printed Silk Fibroin‐Cellulose Dressings for Ischemic Wounds
Advanced Healthcare Materials, EarlyView.3D‐printed wound dressings combining carboxymethyl cellulose, silk fibroin, and growth hormone accelerate healing in diabetic ulcers. These bioactive, customizable dressings enhance angiogenesis, cellular proliferation, and immune modulation. Proteomic analysis reveals activation of regenerative pathways and reduced fibrosis, highlighting their ...
Maria Pita‐Vilar +7 more
wiley +1 more source
Patient experiences of buprenorphine dispensing from a mobile medical unit
Addiction Science & Clinical PracticeBackground Overdose deaths continue to rise within the United States, despite effective treatments such as buprenorphine and methadone for opioid use disorder (OUD).
Sarah E. Messmer +11 more
doaj +1 more source
A Guide to Expanding the Use of Buprenorphine Beyond Standard Initiations for Opioid Use Disorder
Drugs in R&D, 2023 Buprenorphine has become an important medication in the context of the ongoing opioid epidemic. However, complex pharmacologic properties and varying government regulations create barriers to its use.
James C. Miller +4 more
doaj +1 more source
Drug and Alcohol Dependence Reports, 2023 Background: Amidst an unprecedented overdose epidemic, the opioid partial agonist buprenorphine is a medication for opioid use disorder associated with reductions in overdose.
Brandon del Pozo +6 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.Recent advances in diagnostics have accelerated the development of miniaturized wearable technologies for the continuous monitoring of diseases. This paradigm is shifting healthcare away from invasive, centralized blood tests toward decentralized monitoring, using alternative body biofluids.
Lanka Tata Rao +2 more
wiley +1 more source
Safety and Efficacy of Buprenorphine-Naloxone in Pregnancy: A Systematic Review of the Literature
Pathophysiology, 2023 The prevalence of opioid use among pregnant people has been increasing over the past few decades, with a parallel increase in the rate of neonatal abstinence syndrome.
Alice Ordean, Meara Tubman-Broeren
doaj +1 more source