Results 81 to 90 of about 43,211 (293)

Retrospective analysis of heroin detoxification with buprenorphine in a psychiatric hospital in Japan

Neuropsychopharmacology Reports, 2020
Aim We assessed the efficacy of buprenorphine replacement taper therapy in a psychiatric hospital in Japan. Methods Based on the medical records, a retrospective analysis was performed to evaluate the outcomes of buprenorphine replacement taper therapy ...
Tatsushi Nagano, Sohei Kimoto, Katsuro Aso, Takashi Komori, Yasunari Yamaguchi, Kazuya Okamura, Noriya Yamamoto, Toshifumi Kishimoto   +7 more
doaj   +1 more source

Trends in analgesia prescribing in primary care in Ireland and England between 2014 and 2022: A repeated cross‐sectional study

British Journal of Clinical Pharmacology, EarlyView.
Aims Analgesic medicines are an important component of pain management, with different medicines carrying different risks and benefits. The aim of this study was to examine trends in analgesic prescribing in Ireland and England between 2014 and 2022. Methods Monthly data on medicines prescribed and dispensed in primary care were used. For Ireland, data
Molly Mattsson, Michelle Flood, Brian MacKenna, Emma Wallace, Fiona Boland, Ciara Kirke, Mary E. Walsh, Tom Fahey, Frank Moriarty   +8 more
wiley   +1 more source

Development of opioid analgesic tolerance in rat to extended-release buprenorphine formulated for laboratory subjects.

PLoS ONE
Buprenorphine in an extended-release formulation intended for use in laboratory subjects is frequently administered to rats to provide extended analgesia without repeated handling.
Christina M Larson, Cecilia Barajas, Kelley F Kitto, George L Wilcox, Carolyn A Fairbanks, Cristina D Peterson   +5 more
doaj   +1 more source

Trends in opioid prescribing in Scandinavian countries from 2010 to 2023: Insights from multi‐metric evaluation

British Journal of Clinical Pharmacology, EarlyView.
Aims Monitoring opioid prescribing across different healthcare systems is essential to understanding population‐level exposure and informing global health policies. This study examined opioid utilization in Scandinavian countries between 2010 and 2023 using multiple complementary metrics, addressing the limitations of single‐metric comparisons ...
Gabriela Rolová, Svetlana Skurtveit, Marte Handal, Geana Paula Kurita, Torgeir Gilje Lid, Ingvild Odsbu, Mikael Hoffmann   +6 more
wiley   +1 more source

Revised dose schema of sublingual buprenorphine in the treatment of the neonatal opioid abstinence syndrome. [PDF]

, 2011
AIMS: More than half of infants exposed to opioids in utero develop neonatal abstinence syndrome (NAS) of severity to require pharmacological therapy. Current treatments are associated with prolonged hospitalization.
Abdel-Latif, Agthe, American Academy of Pediatrics Committee on Drugs, Blaser, Coghlan, Colombini, Coyle, Crocetti, Dryden, Dysart, Finnegan, Jackson, Jansson, Johnson, Jones, Kraft, Lainwala, Langenfeld, Mamelle, Nandakumar, O'Grady, Oei, Osborn, Osborn, Sarkar, Seligman, Sutton   +26 more
core   +2 more sources

Antihyperalgesic Effect of Buprenorphine Involves Nociceptin/Orphanin FQ Peptide–Receptor Activation in Rats With Spinal Nerve Injury–Induced Neuropathy

Journal of Pharmacological Sciences, 2013
.: We evaluated the effect of buprenorphine, a mixed agonist for μ-opioid receptors and nociceptin/orphanin FQ peptide (NOP) receptors, in neuropathic rats, using the paw pressure test. Buprenorphine, administered i.p. at 50, but not 20, μg/kg, exhibited
Tomoko Takahashi, Kazumasa Okubo, Shota Kojima, Hiroyuki Nishikawa, Motohide Takemura, Maho Tsubota-Matsunami, Fumiko Sekiguchi, Atsufumi Kawabata   +7 more
doaj   +1 more source

Deprescribing drugs with anticholinergic effects in older patients with increased risk of dementia in the multicomponent intervention study AgeWell.de

British Journal of Clinical Pharmacology, EarlyView.
Aim Drugs with anticholinergic effects are often considered as potentially inappropriate medications, especially for older patients, and deprescribing such drugs may improve cognitive function. The aim was to investigate the effectiveness of counselling on drug risks as part of a multimodal intervention to prevent cognitive decline. Methods The AgeWell.
Laura K. Lepenies, Hanna M. Seidling, Alexander Pabst, Melanie Luppa, Juliane Döhring, Martin Williamson, Thomas Frese, Jochen Gensichen, Wolfgang Hoffmann, Hanna Kaduszkiewicz, Hans‐Helmut König, Jochen René Thyrian, Birgitt Wiese, Steffi G. Riedel‐Heller, David Czock   +14 more
wiley   +1 more source

Evaluating the impact of a national naloxone programme on ambulance attendance at overdose incidents: a controlled time-series analysis [PDF]

, 2017
Background and Aims: It has been suggested that distributing naloxone to people who inject drugs (PWID) will lead to fewer attendances by emergency medical services at opioid-related overdose incidents if peer administration of naloxone was perceived ...
Ashworth, Becketti, Bennett, Bird, Box, Clark, Craig, Darke, Darke, Davoli, Jarosz, Knowlton, Lankenau, Lenton, Longo, McAuley, McAuley, McCain, Merchant, Merrall, Moore, Salmon, Seal, Shermann, Sporer, Strang, Walley, Weatherburn, World Health Organization (WHO), Wright   +29 more
core   +2 more sources

Treatment setting and buprenorphine discontinuation: an analysis of multi-state insurance claims

Addiction Science & Clinical Practice
Background Potential differences in buprenorphine treatment outcomes across various treatment settings are poorly characterized in multi-state administrative data.
Kevin Y. Xu, Alex K. Gertner, Shelly F. Greenfield, Arthur Robin Williams, Richard A. Grucza   +4 more
doaj   +1 more source

Innovative transdermal drug delivery systems: Benefits, challenges, and emerging application

BMEMat, EarlyView.
The graphical abstract illustrates the diverse nanostructures employed in transdermal drug delivery systems, highlighting their unique mechanisms to penetrate the intricate layers of skin. It provides a detailed representation of the skin's complex anatomy, emphasizing the challenges posed by its barrier properties.
Syed Waqas Ali Shah, Xingxing Li, Hao Yuan, Huiling Shen, Shaohao Quan, Guifang Pan, Muhammad Ishfaq, Abid Ullah Shah, Hanhan Xie, Jundong Shao   +9 more
wiley   +1 more source