Results 111 to 120 of about 40,708 (270)

Pilot Safety Evaluation of Varenicline for the Treatment of Methamphetamine Dependence. [PDF]

, 2009
Despite the worldwide extent of methamphetamine dependence, no medication has been shown to effectively treat afflicted individuals. One relatively unexplored approach is modulation of cholinergic system function.
Clement, Clayton, De La Garza, Richard, London, Edythe D, Miotto, Karen, Newton, Thomas F, Sevak, Rajkumar J, Shoptaw, Steven, Swanson, Aimee-Noelle, Zorick, Todd   +8 more
core  

An Evaluation of the Drug Interaction Potential of Encorafenib in Combination With Binimetinib Using the Inje Cocktail in Patients With Cancer

Clinical Pharmacology &Therapeutics, Volume 119, Issue 2, Page 375-380, February 2026.
A clinical drug–drug interaction (DDI) study was designed to evaluate the effect of single and multiple oral doses of encorafenib on the single oral dose pharmacokinetics (PK) of the cytochrome P450 (CYP) enzyme probe substrates, losartan (CYP2C9), midazolam (CYP3A4), caffeine (CYP1A2), omeprazole (CYP2C19), and dextromethorphan (CYP2D6) administered ...
Joseph Piscitelli, Micaela B. Reddy, Lance Wollenberg, Laurence Del Frari, Jason Gong, Kyle Matschke, Jason H. Williams   +6 more
wiley   +1 more source

The use of bupropion SR in cigarette smoking cessation

International Journal of COPD, 2008
Scott WilkesDepartment of Primary and Community Care, School of Health, Natural and Social Sciences, University of Sunderland, Sunderland, United KingdomAbstract: Cigarette smoking remains the largest preventable cause of premature death in developed ...
Scott Wilkes
doaj  

Distinct Roles of Dopamine and Noradrenaline in Physical Fatigue

European Journal of Sport Science, Volume 26, Issue 2, February 2026.
ABSTRACT This triple‐blinded randomized crossover study investigated the roles of dopamine (DA) and noradrenaline (NA) in regulating exercise performance and fatigue using acute pharmacological manipulation. Eighteen healthy adults (9 males and 9 females; mean age = 23.4 ± 2.2 years) completed three experimental conditions.
Y. Laurisa Arenales Arauz, Ana Mali, Elke Lathouwers, Jelle Habay, Leonardo de Sousa Fortes, Romain Meeusen, Uros Marusic, Kevin De Pauw, Bart Roelands   +8 more
wiley   +1 more source

Comparison of the effectiveness of bupropion versus buspirone in the treatment of hypoactive sexual desire in women, a randomized clinical trial [PDF]

, 2018
Franklin José Espitia De La Hoz
openalex   +1 more source

Supportive Care Needs Among Pretreatment Head and Neck Cancer Patients According to Smoking Status: A Cross‐Sectional Study With Nested Analyses

Laryngoscope Investigative Otolaryngology, Volume 11, Issue 1, February 2026.
ABSTRACT Objective New head and neck cancer (HNC) patients may prioritize “competing” supportive care needs (SCNs) over smoking cessation, yet the burden of these SCNs according to smoking status is poorly characterized. We aimed to address this gap in knowledge.
Dalia N. Mitchell, Aniah Jefferson, Justin Pyne, Amy Ho, Ayush G. Iyer, Baran D. Sumer, David Balis, Sharika Kumar, Robert Schnoll, Andrew T. Day   +9 more
wiley   +1 more source

Efficacy of the cigarette-burning application combined with medication intervention for smoking cessation in China: A randomized controlled trial

Digital Health
Background Although smartphone application for smoking cessation was considered a promising strategy, there were scarce studies on the combination of usual interventions and apps for smoking cessation in China. Our study aimed to evaluate the efficacy of
Xiao-Wen Wei, Rui Qin, Yong-Zhuang Liu, Zhao Liu, An-Qi Cheng, Xin-Mei Zhou, Zheng Su, Zi-Yang Cui, Jin-Xuan Li, Liang Zhao, Dan Xiao, Chen Wang   +11 more
doaj   +1 more source

Efficacy and safety of varenicline and bupropion, in combination and alone, for alcohol use disorder: a randomized, double-blind, placebo-controlled multicentre trialResearch in context

The Lancet Regional Health. Europe
Summary: Background: Alcohol use disorder (AUD) is associated with an enormous burden of disease and cost to society. The dopamine deficiency hypothesis posits that negative reinforcement generated by a low brain dopamine state drives ethanol intake ...
Bo Söderpalm, Helga Lidö, Johan Franck, Anders Håkansson, Daniel Lindqvist, Markus Heilig, Joar Guterstam, Markus Samuelson, Barbro Askerup, Cecilia Wallmark-Nilsson, Andrea de Bejczy   +10 more
doaj   +1 more source

<p>Promising Swellable Floating Bupropion Tablets: Formulation, in vitro/in vivo Evaluation and Comparative Pharmacokinetic Study in Human Volunteers</p>

, 2020
Mahmoud H. Teaima, Magdi M. Abdel Hamid, Nabil A. Shoman, Bhaskara Jasti, Mohamed A. El-Nabarawi   +4 more
openalex   +2 more sources

Efficacy and Safety of Pharmacological, Endoscopic, and Surgical Treatments for Obesity: A GRADE‐Based Network Meta‐Analysis

Obesity, Volume 34, Issue 2, Page 279-293, February 2026.
ABSTRACT Objective This review compared antiobesity strategies—obesity management medications (OMM), endoscopic bariatric procedures (EBP), and metabolic bariatric surgery (MBS)—with lifestyle intervention, placebo, or no therapy (LSI/Pbo/NT). Methods This network meta‐analysis included randomized clinical trials comparing OMM, EBP, and MBS versus LSI ...
Maurizio De Luca, Ricardo V. Cohen, Amanda Belluzzi, Giuseppe Navarra, Nicola Di Lorenzo, Tarissa B. Z. Petry, Paolo Sbraccia, Luca Busetto, Silvio Buscemi, Rocco Barazzoni, Benedetta Ragghianti, Edoardo Mannucci, Matteo Monami   +12 more
wiley   +1 more source