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Host-pathogen interactions between Burkholderia species and lung epithelial cells [PDF]
Members of the Burkholderia species can cause a range of severe, often fatal, respiratory diseases. A variety of in vitro models of infection have been developed in an attempt to elucidate the mechanism by which Burkholderia spp.
Jonathan eDavid +3 more
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Evaluation of combination therapy for Burkholderia cenocepacia lung infection in different in vitro and in vivo models [PDF]
Burkholderia cenocepacia is an opportunistic pathogen responsible for life-threatening infections in cystic fibrosis patients. B. cenocepacia is extremely resistant towards antibiotics and therapy is complicated by its ability to form biofilms.
Brackman, Gilles +10 more
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The genus Burkholderia contains over 80 different Gram-negative species including both plant and human pathogens, the latter of which can be classified into one of two groups: the Burkholderia pseudomallei complex (Bpc) or the Burkholderia cepacia ...
Irum Syed, R. Mark Wooten
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Thinking Outside the Bug: Targeting Outer Membrane Proteins for Burkholderia Vaccines
Increasing antimicrobial resistance due to misuse and overuse of antimicrobials, as well as a lack of new and innovative antibiotics in development has become an alarming global threat.
Megan E. Grund +4 more
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Current Advances in Burkholderia Vaccines Development
The genus Burkholderia includes a wide range of Gram-negative bacterial species some of which are pathogenic to humans and other vertebrates. The most pathogenic species are Burkholderia mallei, Burkholderia pseudomallei, and the members of the ...
Guanbo Wang +2 more
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Burkholderia cepacia complex (BCC) represent a group of opportunistic organisms that cause a wide variety of infections including the nosocomial.
Anuradha De +4 more
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New Auranofin Analogs with Antibacterial Properties against Burkholderia Clinical Isolates
Bacteria of the genus Burkholderia include pathogenic Burkholderia mallei, Burkholderia pseudomallei and the Burkholderia cepacia complex (Bcc). These Gram-negative pathogens have intrinsic drug resistance, which makes treatment of infections difficult ...
Dustin Maydaniuk +7 more
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Intra-abdominal Abscesses by Burkholderia cepacia in Poorly Controlled Diabetes Mellitus: A Case Series [PDF]
Burkholderia is a gram-negative bacillus causing infections in immunocompromised patients. It is commonly seen in the tropics and is known to mimic tuberculosis clinically.
Aditya Dhanawat +3 more
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T6SS-5 and the cGAS-STING pathway in Burkholderia pseudomallei infection and immunity
Burkholderia pseudomallei is a causative agent of melioidosis that can infect humans and animals in endemic countries, specifically in Southeast Asia and tropical Australia. A fundamental component for the pathogenesis of Burkholderia pseudomallei is the
Noreafifah Semail +6 more
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The great mimicker “Burkholderia cepacia”: A case of intra-abdominal abscesses [PDF]
Burkholderia cepacia infections are underreported and often seen in immunocompromised or cystic fibrosis patients. We describe a case of intra-abdominal abscesses and bacteraemia due to Burkholderia cepacia in a non-cystic fibrosis patient. A middle aged
Divya Prabhu +3 more
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