Autotransporters and their role in the virulence of Burkholderia pseudomallei and Burkholderia mallei. [PDF]
Frontiers in Cellular and Infection Microbiology, 2011 Burkholderia pseudomallei and Burkholderia mallei are closely related Gram-negative bacteria responsible for the infectious diseases melioidosis and glanders, respectively.
Natalie eLazar Adler +3 more
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Oropharyngeal aspiration of Burkholderia mallei and Burkholderia pseudomallei in BALB/c mice. [PDF]
PLoS ONE, 2014 Burkholderia mallei and Burkholderia pseudomallei are potentially lethal pathogens categorized as biothreat agents due, in part, to their ability to be disseminated via aerosol.
Kevin L Schully +3 more
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Development of Burkholderia mallei and pseudomallei vaccines [PDF]
Frontiers in Cellular and Infection Microbiology, 2013 B. mallei and B. pseudomallei are Gram-negative bacteria that cause glanders and melioidosis, respectively. Inhalational infection with either organism can result in severe and rapidly fatal pneumonia.
Ediane Batista Silva, Steven eDow
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Use of the common marmoset to study Burkholderia mallei infection. [PDF]
PLoS ONE, 2015 Burkholderia mallei is a host-adapted bacterium that does not persist outside of its equine reservoir. The organism causes the zoonosis glanders, which is endemic in Asia, Africa, the Middle East and South America. Infection by B. mallei typically occurs
Tomislav Jelesijevic +9 more
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Innate immune response to Burkholderia mallei. [PDF]
Curr Opin Infect Dis, 2017 Purpose of review Burkholderia mallei is a facultative intracellular pathogen that causes the highly contagious and often the fatal disease, glanders. With its high rate of infectivity via aerosol and recalcitrance toward antibiotics, this pathogen is considered a potential biological threat ...
Saikh KU, Mott TM.
europepmc +4 more sources
Recombinant Salmonella Expressing Burkholderia mallei LPS O Antigen Provides Protection in a Murine Model of Melioidosis and Glanders. [PDF]
PLoS ONE, 2015 Burkholderia pseudomallei and Burkholderia mallei are the etiologic agents of melioidosis and glanders, respectively. These bacteria are highly infectious via the respiratory route and can cause severe and often fatal diseases in humans and animals. Both
Dina A Moustafa +7 more
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A Unique Set of the Burkholderia Collagen-Like Proteins Provides Insight into Pathogenesis, Genome Evolution and Niche Adaptation, and Infection Detection. [PDF]
PLoS ONE, 2015 Burkholderia pseudomallei and Burkholderia mallei, classified as category B priority pathogens, are significant human and animal pathogens that are highly infectious and broad-spectrum antibiotic resistant.
Beth A Bachert +11 more
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Current Advances in Burkholderia Vaccines Development
Cells, 2020 The genus Burkholderia includes a wide range of Gram-negative bacterial species some of which are pathogenic to humans and other vertebrates. The most pathogenic species are Burkholderia mallei, Burkholderia pseudomallei, and the members of the ...
Guanbo Wang +2 more
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Alanine racemase mutants of Burkholderia pseudomallei and Burkholderia mallei and use of alanine racemase as a non-antibiotic-based selectable marker. [PDF]
PLoS ONE, 2011 Burkholderia pseudomallei and Burkholderia mallei are category B select agents and must be studied under BSL3 containment in the United States. They are typically resistant to multiple antibiotics, and the antibiotics used to treat B.
Sheryl L W Zajdowicz +5 more
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Virulence, 2021 We recently described a protein O-glycosylation pathway conserved in all species of the Burkholderia genus that results in the synthesis and incorporation of a trisaccharide glycan to membrane-exported proteins.
Guanbo Wang +6 more
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