Results 61 to 70 of about 69,937 (307)
Advanced Science, EarlyView.FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni +17 more
wiley +1 more source
Prediction Intervals for Generalized Burr Regression Models [PDF]
The Egyptian Statistical Journal, 1992 In this paper, equal-tailed two-sided prediction intervals are developed for generalized Burr type XII, or log-Burr regression model. A useful parameterization given by Gould and Lawless (1988) is used to write the log-Burr model as a location-scale ...
Mohamed Abdelhafez
doaj +1 more source
Sonoselective Transfection of Glioma Endothelium
Advanced Science, EarlyView.Delivering non‐viral, gene‐bearing nanoparticles with thiol‐decorated surfaces to gliomas with focused ultrasound yields transfection tropism for endothelial cells. From this platform, “sonoselective” transfection of glioma endothelium is achieved via incorporation of an endothelial cell‐specific promoter.
Anna C. Debski +8 more
wiley +1 more source
Journal of Manufacturing and Materials ProcessingSeveral challenges arise during edge trimming of carbon fibre-reinforced polymer (CFRP) composites, such as the formation of machining-induced burrs and delamination.
Tamás Sándor Tima, Norbert Geier
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Advanced Science, EarlyView.eCIRP released in the stroke brain binds to TLR4 expressed on microglia to induce miR‐155, which suppresses MafB, decreases MerTK and downstream signaling to impair efferocytosis of apoptotic neurons, worsening the acute stroke outcomes. Inhibition of eCIRP‐TLR4 interaction with small peptide C23 attenuates eCIRP‐induced microglial efferocytic ...
Dmitriy Lapin +3 more
wiley +1 more source
An evolutionarily conserved function of polycomb silences the MHC class I antigen presentation pathway and enables immune evasion in cancer [PDF]
Source data: Western blot scans to accompany Burr et al., An Evolutionarily Conserved Function of Polycomb Silences the MHC Class I Antigen Presentation Pathway and Enables Immune Evasion in Cancer, Cancer Cell (2019), https://doi.org/10.1016/j.ccell ...
Burr, M
core +1 more source
Aaron Burr Jr. and John Pierre Burr: A Founding Father and his Abolitionist Son [PDF]
, 2020 Aaron Burr Jr. (Class of 1772), the third Vice President of the United States, fathered two children by a woman of color from Calcutta, India. Their son, John Pierre Burr (1792-1864), would become an activist, abolitionist, and conductor on the ...
Burr, Sherri
core
Effects of Input Parameters on the Hole Quality During the Drilling of Al Metal Matrix Composites
DesignsThe extensive industrial applications of aluminum (Al) metal matrix composites (MMCs) require optimal drilling conditions in the manufacturing industries.
Alokesh Pramanik, Animesh Kumar Basak
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Advanced Intelligent Discovery, EarlyView.This perspective highlights how knowledge‐guided artificial intelligence can address key challenges in manufacturing inverse design, including high‐dimensional search spaces, limited data, and process constraints. It focused on three complementary pillars—expert‐guided problem definition, physics‐informed machine learning, and large language model ...
Hugon Lee +3 more
wiley +1 more source
Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.Herein, a patient‐mounted neuro optical coherence tomography system that integrates a 5 degrees‐of‐freedom skull‐mounted robot (Skullbot) with a 0.6 mm neuroendoscope for targeted, minimally invasive deep brain imaging, is developed. The system offers high‐resolution imaging with precise deployment, demonstrated through successful tumor imaging in a ...
Chao Xu +7 more
wiley +1 more source