Results 21 to 30 of about 18,506 (177)
, 1994 OBJECTIVE: TO review the current published studies evaluating the pharmacokinetics, clinical efficacy, safety, and toxicity of busulfan in pediatric and adult patients.DATA SOURCES: English-language literature published between 1953 and 1993 was analyzed;
Locatelli, F
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The Safe Recipient of SSC Transplantation Prepared by Heat Shock With Busulfan Treatment in Mice
Cell Transplantation, 2018 Safety is the chief consideration in recipient preparation of spermatogonial stem cell (SSC) transplantation in mammals, especially humans. In this study, we compared the safety of the SSC transplantation recipients that were prepared both by testes heat
Wenzhi Ma, Jia Wang, Weijun Gao, Hua Jia
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Side effects of treatment with busulfan at high doses in dogs
Journal of Animal Reproduction and Biotechnology, 2022 Busulfan is the most commonly used drug for preconditioning during the transplantation of hematopoietic stem cells and male germ cells. Here, we describe side effects of high doses of busulfan in male mongrel dogs. Busulfan was intravenously administered
Tai-Young Hur +4 more
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Effects of Carob (Ceratonia siliqua) on Sperm Quality, Testicular Structure, Testosterone Level and Oxidative Stress in Busulfan-Induced Infertile Mice [PDF]
Pharmaceutical Sciences, 2018 Background: Ceratonia silique has antioxidant activities that may inactivate toxic factors and influence sperm quality. To the best of the authors’ knowledge, there is no available data on the effects of carob on male fertility.
Azadeh Vafaei +5 more
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Frontiers in Nutrition, 2022 Busulfan is currently an indispensable anti-cancer drug, but the side effects on male reproductive system are so serious. Meanwhile, red-fleshed apples are natural products with high anthocyanin content.
Bin Wang +8 more
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Prediction of Busulfan Clearance by Predose Plasma Metabolomic Profiling [PDF]
, 2023 Intravenous busulfan doses are often personalized to a target plasma exposure (targeted busulfan) using an individual's busulfan clearance (BuCL). We evaluated whether BuCL could be predicted by a predose plasma panel of 841 endogenous metabolomic ...
Navarro, Sandi L. +12 more
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Case Report: Remission of Chronic Idiopathic Myelofibrosis to Busulfan Treatment [PDF]
, 1988 Three patients with chronic idiopathic myelofibrosis have responded to busulfan treatment with an excellent hematologic remission and reversal of myelofibrosis and myeloid metaplasia.
Chang, Jae C, Gross, Howard M
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Busulfan Interlaboratory Proficiency Testing Program Revealed Worldwide Errors in Drug Quantitation and Dose Recommendations [PDF]
, 2023 Background:The clinical outcomes of busulfan-based conditioning regimens for hematopoietic cell transplantation (HCT) have been improved by personalizing the doses to target narrow busulfan plasma exposure. An interlaboratory proficiency test program for
van Luin, Matthijs +4 more
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Alginate oligosaccharides ameliorate busulfan-induced renal tubule injury [PDF]
, 2022 Kidney diseases endanger human health and place a heavy burden on global health care systems. The current study aimed to explore the beneficial advances of alginate oligosaccharides (AOS) as a functional food on kidney structure and function, and the ...
Lu, D. +9 more
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Journal of Ginseng Research, 2015 Background: Anticancer agents induce a variety of adverse effects when administered to cancer patients. Busulfan is a known antileukemia agent. When administered for treatment of leukemia in young patients, busulfan could cause damage to the male ...
Seok-Won Jung +14 more
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