Results 91 to 100 of about 6,620 (168)

NRF2 coordinates cystine import and glutathione use to sustain ferroptosis resistance and formaldehyde tolerance in cancer. [PDF]

Sci Adv
Morellato AE, Alquezar-Artieda N, Guerrero-Maldonado A, Singh R, Beja L, Umansky C, Perich-Pallaruelo L, Pellicer M, Fernandez-Deu P, Aira N, Bourached-Silva N, Chorostecki U, Jones DJL, Roué G, Hopkinson RJ, Pontel LB.   +15 more
europepmc   +1 more source

Glutamate-cysteine ligase catalytic related glutathione metabolism inhibited high mobility group box 1 release by regulating epithelium ferroptosis in asthma. [PDF]

J Thorac Dis
Liu H, Zhong C, Jiang X, Yuan Y, Zhang J, Tang H.   +5 more
europepmc   +1 more source

Increases in vascular nitrosylation reduce blood pressure in hypertensive rats and are associated with a decrease in angiotensin-converting enzyme tissue activity. [PDF]

Naunyn Schmiedebergs Arch Pharmacol
Pinheiro LC, Oliveira-Paula GH, Ferreira GC, Moreira DH, Tanus-Santos JE.   +4 more
europepmc   +1 more source

BIMEL is a key effector molecule in oxidative stress-mediated apoptosis in acute myeloid leukemia cells when combined with arsenic trioxide and buthionine sulfoximine. [PDF]

BMC Cancer, 2014
Tanaka Y, Komatsu T, Shigemi H, Yamauchi T, Fujii Y.   +4 more
europepmc   +1 more source

Unlocking ferroptosis heterogeneity: ATF4 versus SREBF transcriptional programs. [PDF]

Cell Death Discov
Barannikova MV, Sulyagin VK, Korzhenevskii DA, Starodubova VD, Sorokina MA, Nesterenko AM, Gazizova GR, Sulyagina VP, Gusev OA, Shagimardanova EI, Belousov VV, Kudryashova OM, Shokhina AG.   +12 more
europepmc   +1 more source

D, L-Buthionine-(S, R)-sulfoximine recapitulates the anti-obesity effects of sulfur amino acid restriction without the associated deleterious effects on bone in male mice. [PDF]

Aging (Albany NY)
Ommi NB, Mattocks DAL, Horowitz MC, Nichenametla SN.   +3 more
europepmc   +1 more source

Lipid Peroxidation Increases Lens Stiffness and Is Associated With αA-Crystallin Accumulation at the Plasma Membrane: An Ex Vivo Study. [PDF]

Invest Ophthalmol Vis Sci
Fan E, Hao C, Zheng S, Zhang M, Fan X.
europepmc   +1 more source

An Update on Oxidative Stress and Redoxins in Pancreatitis. [PDF]

Cell Mol Gastroenterol Hepatol
Assi M.
europepmc   +1 more source

A Study on Enhancement of Hyperthermochemotherapy in the Presence of Buthionine Sulfoximine (BSO)

A Study on Enhancement of Hyperthermochemotherapy in the Presence of Buthionine Sulfoximine (BSO)
The aim of this study was enhancement of the effect of hyperthermia which is a part of the multidisciplinary treatments for carcinomas. Many physicians suffered from practical difficulty in keeping the uniformity of 43℃ in the deep organs. Buthionine sulfoximine (BSO) is a specific inhibitor of glutathione (GSH) synthesis, and suppress GSH activity ...
openaire   +1 more source

Metabolic inhibition of glutamate-cysteine ligase increases dendritic cell-mediated antitumor immunity in melanoma. [PDF]

J Immunother Cancer
Dieckmann SM, Tripp CH, Strandt H, Hornsteiner F, Schäfer AK, Prokopi A, Vierthaler J, Resag A, Ortner-Tobider D, Reinstadler V, Rigato I, Junger B, Kleiter A, Fotakis G, Efremova M, Trajanoski Z, Boon L, Chen S, Bosserhoff AK, Oberacher H, Finotello F, Stoitzner P.   +21 more
europepmc   +1 more source