Gut Microbiota-Derived Short-Chain Fatty Acids in Inflammatory Bowel Disease: Mechanistic Insights into Gut Inflammation, Barrier Function, and Therapeutic Potential. [PDF]
Ottria R, Mirmajidi S, Ciuffreda P.
europepmc +1 more source
Expression of Glycoprotein B (gB) Correlates With Poor Prognosis in Nasopharyngeal Carcinoma
The extent of EBV lytic replication in NPC has not been fully clarified. Our study demonstrated EBV replication and release in NPC and identified a significant association between expression of the late lytic protein gB and poor prognosis. These findings suggest that late lytic gene products may contribute to tumor progression and that gB represents a ...
Shigetaka Komura +24 more
wiley +1 more source
Fecal butyrate and deoxycholic acid quantitation for rapid assessment of the gut microbiome. [PDF]
Mullowney MW +13 more
europepmc +1 more source
Glucose Metabolism Regulating Colorectal Cancer Initiation and Progression
Drugs and compounds targeting glycolysis in CRC and the mechanisms by which these drugs inhibit their respective targets. ABSTRACT Colorectal cancer (CRC) is one of the most common types of invasive cancer worldwide, which has the characteristics of poor curative effect and poor prognosis. Increasing evidence suggests that hyperactivated glucose uptake
Meiyi Lin, Junpeng Cui
wiley +1 more source
<i>Lactobacillus paracasei</i> LP18 ameliorated inflammation and intestinal barrier dysfunction in severe acute pancreatitis via gut microbiota-mediated regulation of butyrate metabolism. [PDF]
Cao J +7 more
europepmc +1 more source
Targeting Inflammation and Immune Regulation in Chronic Inflammation Associated Cancers
Chronic inflammation sustains activation of key inflammatory pathways, including Nuclear factor kappa B (NF‐κB), Interleukin‐6‐signal transducer and activator of transcription 3 (IL6‐STAT3), Phosphoinositide 3‐kinase/Akt (PI3K/Akt), and Wingless/β‐catenin (Wnt/β‐catenin) signaling. This promotes immune dysregulation through the expansion and functional
Lawan Rabiu +5 more
wiley +1 more source
Characterization of the inflammatory response of a canine intestinal epithelial cell line challenged with lipopolysaccharides and/or butyrate. [PDF]
Phimister FD +6 more
europepmc +1 more source
ABSTRACT Background Patch test results obtained with the European Baseline Series (EBS) in its current version serve both contact allergy surveillance and (re‐)assessing the diagnostic value of EBS allergens. Objectives To present results of current EBS patch testing, obtained in 59 departments in 14 European countries during 2021 and 2022.
Wolfgang Uter +73 more
wiley +1 more source
Short-chain fatty acids in the tumor microenvironment: from molecular mechanisms to cancer therapy. [PDF]
Xiang Y, Du A, Wang Z, Pan H, Yuan K.
europepmc +1 more source

