Results 331 to 340 of about 225,175 (395)
Gut Microbes, 2021 Host-microbial cross-talk plays a crucial role in maintenance of gut homeostasis. However, how microbiota-derived metabolites, e.g., butyrate, regulate functions of neutrophils in the pathogenesis of inflammatory bowel disease (IBD) remains elusive.
Gengfeng Li, Huiying Lu, Zhan Ju Liu
exaly +2 more sources
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Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells
Nature, 2013Yukihiro Furusawa +2 more
exaly +2 more sources
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 2022
ALSUntangled reviews alternative and off-label treatments for people living with amyotrophic lateral sclerosis (PALS). Here we review butyrate and its different chemical forms (butyrates). Butyrates have plausible mechanisms for slowing ALS progression and positive pre-clinical studies.
Yuyao Sun +19 more
openaire +2 more sources
ALSUntangled reviews alternative and off-label treatments for people living with amyotrophic lateral sclerosis (PALS). Here we review butyrate and its different chemical forms (butyrates). Butyrates have plausible mechanisms for slowing ALS progression and positive pre-clinical studies.
Yuyao Sun +19 more
openaire +2 more sources
The Short Chain Fatty Acid Butyrate Imprints an Antimicrobial Program in Macrophages
Immunity, 2019 &NA; Host microbial crossâtalk is essential to maintain intestinal homeostasis. However, maladaptation of this response through microbial dysbiosis or defective host defense toward invasive intestinal bacteria can result in chronic inflammation.
Fanny Franchini +2 more
exaly +2 more sources
Butyrate in Energy Metabolism: There Is Still More to Learn
Trends in Endocrinology and Metabolism, 2021Butyrate, a main product of gut microbial fermentation, has been recognized as an important mediator of gut microbiota regulation in whole body energy homeostasis. However, the mechanisms of butyrate metabolic control remain unclear.
Qingyan Jiang, Yulong Yin
exaly +2 more sources
Hepatology, 2023
Background and Aims: Gut microbiota are recognized to be important for anticancer therapy, yet the underlying mechanism is not clear. Here, through the analysis of clinical samples, we identify the mechanism by which the gut microbial metabolite butyrate
Yibin Che +5 more
semanticscholar +1 more source
Background and Aims: Gut microbiota are recognized to be important for anticancer therapy, yet the underlying mechanism is not clear. Here, through the analysis of clinical samples, we identify the mechanism by which the gut microbial metabolite butyrate
Yibin Che +5 more
semanticscholar +1 more source
Immunity
Tuft cells in mucosal tissues are key regulators of type 2 immunity. Here, we examined the impact of the microbiota on tuft cell biology in the intestine.
Taylor Rice +2 more
exaly +2 more sources
Tuft cells in mucosal tissues are key regulators of type 2 immunity. Here, we examined the impact of the microbiota on tuft cell biology in the intestine.
Taylor Rice +2 more
exaly +2 more sources
Current Opinion in Clinical Nutrition and Metabolic Care, 2012
Butyrate is physiologically produced by the microbial fermentation of dietary fibers and plays a plurifunctional role in intestinal cells. This review examines the recent findings regarding the role and mechanisms by which butyrate regulates intestinal metabolism and discusses how these findings could improve the treatment of several gastrointestinal ...
Alda J, Leonel +1 more
openaire +2 more sources
Butyrate is physiologically produced by the microbial fermentation of dietary fibers and plays a plurifunctional role in intestinal cells. This review examines the recent findings regarding the role and mechanisms by which butyrate regulates intestinal metabolism and discusses how these findings could improve the treatment of several gastrointestinal ...
Alda J, Leonel +1 more
openaire +2 more sources
Annals of the New York Academy of Sciences, 1998
Abstract: The aims of this study were to ascertain tolerability, safety and efficacy of oral isobutyramide (150 mg/kg bw/day) in stimulating fetal hemoglobin production in twelve thalassemia intermedia patients. Patients were treated for 28 days and followed for a further 28 days.
M D, Cappellini +6 more
openaire +2 more sources
Abstract: The aims of this study were to ascertain tolerability, safety and efficacy of oral isobutyramide (150 mg/kg bw/day) in stimulating fetal hemoglobin production in twelve thalassemia intermedia patients. Patients were treated for 28 days and followed for a further 28 days.
M D, Cappellini +6 more
openaire +2 more sources
Clinical science, 2022
Ulcerative colitis (UC) is majorly associated with dysregulation of the dynamic cross-talk among microbial metabolites, intestinal epithelial cells, and macrophages.
Liping Liang +6 more
semanticscholar +1 more source
Ulcerative colitis (UC) is majorly associated with dysregulation of the dynamic cross-talk among microbial metabolites, intestinal epithelial cells, and macrophages.
Liping Liang +6 more
semanticscholar +1 more source